Journal ArticleDOI
Long noncoding RNA RP11-766N7.4 functions as a tumor suppressor by regulating epithelial-mesenchymal transition in esophageal squamous cell carcinoma.
TLDR
This study suggested that long noncoding RNA RP11-766N7.4 acts as a tumor suppressor in ESCC carcinogenesis and metastasis, and may be a potential prognostic mark and a therapeutic target for ESCC.About:
This article is published in Biomedicine & Pharmacotherapy.The article was published on 2017-04-01. It has received 21 citations till now. The article focuses on the topics: RNA & Long non-coding RNA.read more
Citations
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CCAT1 promotes triple-negative breast cancer progression by suppressing miR-218/ZFX signaling.
TL;DR: The data indicate that CCAT1 promotes TNBC progression by targeting the miR-218/ZFX axis, and identifies the zinc finger protein ZFX as a putative downstream target of microRNA-218 through bioinformatics analysis.
Journal ArticleDOI
MiR-30c-5p suppresses migration, invasion and epithelial to mesenchymal transition of gastric cancer via targeting MTA1.
TL;DR: The results indicate that miR-30c-5p, a novel suppressor in tumorigenesis, could inhibit the metastasis and EMT via MTA1, which may offer a possible therapeutic target in GC.
Journal ArticleDOI
Downregulation of SNHG1 suppresses cell proliferation and invasion by regulating Notch signaling pathway in esophageal squamous cell cancer.
TL;DR: It is demonstrated that lncRNA SNHG1 may be a potential predictor of prognosis in ESCC patients and a novel target for ESCC treatment and knockdown of SNHg1 suppressed the Notch signaling pathway by reducing the NotCh1 and Hes-1 expression levels in ES CC cells.
Journal ArticleDOI
Emerging Role of Non-Coding RNAs in Esophageal Squamous Cell Carcinoma.
TL;DR: Findings are discussed and summarized that interactions of ncRNAs are evident in ESCC, as miRNAs regulate the expression of lncRNAs, and further, lnc RNAs and circRNAs function as miRNA sponges to compete with the endogenous RNAs.
Journal ArticleDOI
Long noncoding RNA lnc-ABCA12-3 promotes cell migration, invasion, and proliferation by regulating fibronectin 1 in esophageal squamous cell carcinoma.
Junliang Ma,Junliang Ma,Yuhang Xiao,Bo Tian,Shaolin Chen,Baihua Zhang,Jie Wu,Zhining Wu,Xu Li,Jinming Tang,Desong Yang,Yong Zhou,Hui Wang,Min Su,Wenxiang Wang +14 more
TL;DR: The results suggest that lnc‐ABCA12‐3 is a novel oncogene in tumorigenesis and that its high expression is related to a poor prognosis for patients with ESCC.
References
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Journal ArticleDOI
Analysis of relative gene expression data using real-time quantitative pcr and the 2(-delta delta c(t)) method
TL;DR: The 2-Delta Delta C(T) method as mentioned in this paper was proposed to analyze the relative changes in gene expression from real-time quantitative PCR experiments, and it has been shown to be useful in the analysis of realtime, quantitative PCR data.
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TL;DR: The overall cancer death rate decreased from 215.1 (per 100,000 population) in 1991 to 168.7 in 2011, a total relative decline of 22%.
Journal ArticleDOI
Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation
Marcel E. Dinger,Paulo P. Amaral,Tim R. Mercer,Ken C Pang,Ken C Pang,Stephen J. Bruce,Brooke Gardiner,Brooke Gardiner,Marjan E. Askarian-Amiri,Kelin Ru,Giulia Soldà,Giulia Soldà,Cas Simons,Susan M. Sunkin,Mark L. Crowe,Sean M. Grimmond,Andrew C. Perkins,John S. Mattick +17 more
TL;DR: The data indicate that long ncRNAs are likely to be important in processes directing pluripotency and alternative differentiation programs, in some cases through engagement of the epigenetic machinery.