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Open AccessJournal ArticleDOI

Magnetic Resonance Imaging/Ultrasound-Fusion Biopsy Significantly Upgrades Prostate Cancer Versus Systematic 12-core Transrectal Ultrasound Biopsy

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TLDR
MRI/US-fusion-guided biopsy upgrades and detects PCa of higher Gleason score in 32% of patients compared with traditional 12-core biopsy alone, and preferentially detects higher-grade PCa while missing lower-grade tumors.
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This article is published in European Urology.The article was published on 2013-11-01 and is currently open access. It has received 460 citations till now. The article focuses on the topics: Image-Guided Biopsy & Biopsy.

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Citations
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Journal ArticleDOI

How to select the right patients for focal therapy of prostate cancer

TL;DR: Enrollment for focal therapy protocols should encourage patient education on the need of possible subsequent cycles of ablation as well as the need for surveillance of the untreated prostatic tissue, as prostate cancer is transformed into a chronic, manageable condition.
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Pretreatment 3T multiparametric MRI staging predicts for biochemical failure in high-risk prostate cancer treated with combination high-dose-rate brachytherapy and external beam radiotherapy.

TL;DR: For high-risk prostate cancer treated with combination HDR brachytherapy and EBRT, mpMRI evidence of SVI predicted for biochemical failure, whereas traditional pretreatment variables did not, and pretreatment 3T mpMRI appears useful for identifying men who may benefit from treatment intensification.
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Navigating MRI-TRUS fusion biopsy: optimizing the process and avoiding technical pitfalls

TL;DR: MRI-TRUS (trans-rectal ultrasound) fusion biopsy is an in-office procedure that promises to empower urologists to successfully target these MRI-visible lesions for histological confirmation and the moving parts in the process are described.
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PI-RADS v2 and ADC values: is there room for improvement?

TL;DR: ADC values and categories help to diagnose CS-PCa when lesions are assigned a PI-RADS v2 score of 4, and analysis of the ROC curves shows that the main benefit of utilizing ADC values or categories is better discrimination ofPI-R ADS v2 4 lesions.
Journal ArticleDOI

Optimizing Patient Population for MP-MRI and Fusion Biopsy for Prostate Cancer Detection

TL;DR: The current knowledge on how to best optimize which men undergo mp-MRI and fusion biopsies both in the screening and treatment settings is summarized.
References
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Journal ArticleDOI

Image-guided prostate biopsy using magnetic resonance imaging-derived targets: a systematic review.

TL;DR: MRI-guided biopsy detects clinically significant prostate cancer in an equivalent number of men versus standard biopsy using fewer biopsies in fewer men, with a reduction in the diagnosis of clinically insignificant cancer.
Journal ArticleDOI

Prostate cancer: value of multiparametric MR imaging at 3 T for detection--histopathologic correlation.

TL;DR: Multiparametric MR imaging of the prostate at 3 T enables tumor detection, with reasonable sensitivity and specificity values, and Generalized estimating equations (GEEs) provided significant independent and additive predictive value when GEEs were used.
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