Manmade Electromagnetic Fields and Oxidative Stress-Biological Effects and Consequences for Health.
David Schuermann,Meike Mevissen +1 more
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In this paper, the authors summarized key experimental findings on oxidative stress related to electromagnetic field exposure from animal and cell studies of the last decade and discussed in the context of molecular mechanisms and functionalities relevant to health such as neurological function, genome stability, immune response, and reproduction.Abstract:
Concomitant with the ever-expanding use of electrical appliances and mobile communication systems, public and occupational exposure to electromagnetic fields (EMF) in the extremely-low-frequency and radiofrequency range has become a widely debated environmental risk factor for health. Radiofrequency (RF) EMF and extremely-low-frequency (ELF) MF have been classified as possibly carcinogenic to humans (Group 2B) by the International Agency for Research on Cancer (IARC). The production of reactive oxygen species (ROS), potentially leading to cellular or systemic oxidative stress, was frequently found to be influenced by EMF exposure in animals and cells. In this review, we summarize key experimental findings on oxidative stress related to EMF exposure from animal and cell studies of the last decade. The observations are discussed in the context of molecular mechanisms and functionalities relevant to health such as neurological function, genome stability, immune response, and reproduction. Most animal and many cell studies showed increased oxidative stress caused by RF-EMF and ELF-MF. In order to estimate the risk for human health by manmade exposure, experimental studies in humans and epidemiological studies need to be considered as well.read more
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Journal ArticleDOI
Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology
Helmut Sies,Vsevolod V. Belousov,Navdeep S. Chandel,Michael J. Davies,Dean P. Jones,Giovanni E. Mann,Michael P. Murphy,Masayuki Yamamoto,Christine C. Winterbourn +8 more
TL;DR: This Expert Recommendation article pinpoints key issues associated with identifying the physiological roles of oxidants, focusing on H2O2 and O2, and stresses that physiological O2 levels should be maintained in cell culture to better mimic in vivo redox reactions associated with specific cell types.
Journal ArticleDOI
Magnetic field effects in biology from the perspective of the radical pair mechanism
TL;DR: An explanation based on the radical pair mechanism, which involves the quantum dynamics of the electron and nuclear spins of transient radical molecules, is suggested for magnetic field effects on various physiological functions as well as isotope effects.
Journal ArticleDOI
Scientific evidence invalidates health assumptions underlying the FCC and ICNIRP exposure limit determinations for radiofrequency radiation: implications for 5G
I. Belyaev,Carl Blackman,Kent Chamberlin,Alvaro DeSalles,Suleyman Dasdag,Claudio Fernández,Lennart Hardell,Paul Héroux,Elizabeth Kelley,Kavindra Kumar Kesari,Don Maisch,Erica Mallery-Blythe,Ronald L. Melnick,A.Z. Miller,Joel M. Moskowitz,Wenjun J. Sun,Igor Yakymenko +16 more
TL;DR: In this article , the past 25 years of extensive research on RFR demonstrates that the assumptions underlying the FCC's and ICNIRP's exposure limits are invalid and continue to present a public health harm.
Journal ArticleDOI
Wireless phone use in childhood and adolescence and neuroepithelial brain tumours: Results from the international MOBI-Kids study
TL;DR: In this paper , a case-control study was conducted to evaluate whether wireless phone use (and particularly resulting exposure to radiofrequency (RF) and extremely low frequency (ELF) electromagnetic fields (EMF)) increases risk of brain tumours in young people.
Journal ArticleDOI
Magnetic Fields and Cancer: Epidemiology, Cellular Biology, and Theranostics
TL;DR: The epidemiology of residential/domestic and occupational exposure to MFs and cancer is reviewed, with reference to leukemia, brain, and breast cancer, and in vivo and in vitro effects of MFs on cancer are reviewed considering both human and animal cells.
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