Metabolism of apigenin and related compounds in the rat. Metabolite formation in vivo and by the intestinal microflora in vitro.
Lesley Griffiths,G. E. Smith +1 more
TLDR
The rat intestinal microflora is capable of effecting degradation of flavonoid compounds to metabolites observed in the urine after oral administration of the specific flavonoids, and all compounds possessing free 5- and 7-hydroxyl groups in the A ring gave rise to ring-fission products, which included 4'-hydroxyphenylacyl derivatives.Citations
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Polyphenols: food sources and bioavailability
TL;DR: The nature and contents of the various polyphenols present in food sources and the influence of agricultural practices and industrial processes are reviewed, and bioavailability appears to differ greatly between the variousPolyphenols, and the most abundantpolyphenols in the authors' diet are not necessarily those that have the best bioavailability profile.
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Determination of malonaldehyde precursor in tissues by thiobarbituric acid test
Mitsuru Uchiyama,Midori Mihara +1 more
TL;DR: It was concluded that the deproteinization of homogenate prior to coloration is not needed, but double wavelength measurement is necessary to avoid interference and the reaction should be performed with phosphoric acid at a definite pH near 2.0.
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Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies
TL;DR: Gallic acid and isoflavones are the most well-absorbed polyphenols, followed by catechins, flavanones, and quercetin glucosides, but with different kinetics, and the least well- absorption polyphenol are the proanthocyanidins, the galloylated tea catech ins, andThe anthocyanins.
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The biochemistry and medical significance of the flavonoids.
TL;DR: Flavonoids are plant pigments that are synthesised from phenylalanine, generally display marvelous colors known from flower petals, mostly emit brilliant fluorescence when they are excited by UV light, and are ubiquitous to green plant cells.
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Dietary agents in cancer prevention: flavonoids and isoflavonoids.
TL;DR: Compelling data suggest that flavones and isoflavones contribute to cancer prevention; however, further investigations will be required to clarify the nature of the impact and interactions between these bioactive constituents and other dietary components.
References
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The carbohydrates of the Jerusalem artichoke and other Compositae.
J. S. D. Bacon,J. Edelman +1 more
TL;DR: In the course of an investigation into the transformations of fructose polysaccharides in the tubers, it is clear from the results presented here that existing ideas about the tuber carbohydrates must be modified.
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The identification of coumarins and related compounds by filter-paper chromatography.
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The metabolic fate of rutin and quercetin in the animal body
TL;DR: The metabolic fate of a flavonoid such as quercetin in animals other than the rabbit was considered especially important in view of the results obtained by Clark and MacKay with rats and humans.
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Microbial growth on oxalate by a route not involving glyoxylate carboligase
TL;DR: Evidence in favour of this scheme is provided by the finding that a mutant of Pseudomonas AM1 that lacks hydroxypyruvate reductase is not able to grow on oxalate, and which indicates that, in contrast with Ps.