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Methotrexate and psoriasis: consensus conference.

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This article is published in Journal of The American Academy of Dermatology.The article was published on 1998-03-01. It has received 360 citations till now. The article focuses on the topics: Psoriasis.

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Etanercept in the treatment of psoriatic arthritis and psoriasis: a randomised trial

TL;DR: Etanercept offers patients with psoriatic arthritis and psoriasis a new therapeutic option for control of their disease.
Journal ArticleDOI

Efficacy and safety results from the randomized controlled comparative study of adalimumab vs. methotrexate vs. placebo in patients with psoriasis (CHAMPION).

TL;DR: This data indicates that once-weekly dosing with adalimumab is a safe and effective treatment for moderate to severe chronic plaque psoriasis in women with atypical immune response to chemotherapy.
Journal ArticleDOI

Risk of malignancies in psoriasis patients treated with cyclosporine: a 5 y cohort study.

TL;DR: Treatment of psoriasis with cyclosporine is associated with an increased risk of nonmelanoma skin cancer and exposure to psoralen and ultraviolet A and to other immunosuppressants was shown to contribute to the overall risk.
Journal ArticleDOI

Obesity in psoriasis: the metabolic, clinical and therapeutic implications. Report of an interdisciplinary conference and review.

TL;DR: How, moving forward, dermatologists and other specialists may redefine the magnitude of health risk associated with more severe psoriasis and its comorbidities is addressed, while clarifying both the epidemiology and pathophysiology of the association with obesity.
Journal ArticleDOI

Current and future management of psoriasis

TL;DR: Management of psoriasis begins with identification of the extent of cutaneous disease, and a holistic, contractual approach to treatment is encouraged, with particular reference to psychosocial disability and quality-of-life issues.
References
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Methotrexate and histologic hepatic abnormalities: a meta-analysis.

TL;DR: A meta-analysis of 15 studies examining the relationship between long-term, low-dose methotrexate administration and biopsy evidence of liver fibrosis was conducted by as discussed by the authors.
Journal Article

Methotrexate and histologic hepatic abnormalities: A meta-analysis

TL;DR: The risk of liver toxicity in patients undergoing long-term, low-dose methotrexate therapy is substantial, and that risk increases with the total cumulative dose and with heavy consumption of alcohol.
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