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Moringa oleifera Lam. in Diabetes Mellitus: A Systematic Review and Meta-Analysis.

TLDR
In this paper, the effect of Moringa oleifera on diabetic hyperglycemia and dyslipidemia was examined by meta-analyzing the current evidence of diabetic rodent models.
Abstract
Plant-derived phytochemicals have been interested in as nutraceuticals for preventing the onset and progress of diabetes mellitus and its serious complications in recent years. Moringa oleifera Lam. is used in vegetables and in herbal medicine for its health-promoting properties against various diseases including diabetes mellitus. This study aimed to examine an effect of Moringa oleifera on diabetic hyperglycemia and dyslipidemia by meta-analyzing the current evidence of diabetic rodent models. Peer-reviewed studies written in English from two databases, PubMed and Embase, were searched to 30 April 2021. Studies reporting blood glucose or lipid levels in diabetic rodents with and without receiving extracts of Moringa oleifera were included. Forty-four studies enrolling 349 diabetic rodents treated with extracts of Moringa oleifera and 350 diabetic controls reported blood glucose levels. The pooled effect size was -3.92 (95% CI: -4.65 to -3.19) with a substantial heterogeneity. This effect was likely to be, at least in part, modified by the type of diabetic models. Moreover, diabetic hypertriglyceridemia and hypercholesterolemia were also significantly improved in diabetic rodent models treated with Moringa oleifera.

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Natural products for the treatment and management of diabetes mellitus in Zimbabwe-a review

TL;DR: A number of studies carried out to evaluate the antidiabetic properties of indigenous plants found in Zimbabwe with the goal of treating diabetes mellitus are highlighted and can open pathways leading to discovery of new plant derived medicines and regularization of use of crude plant remedies.
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A Review on the Antidiabetic Properties of Moringa oleifera Extracts: Focusing on Oxidative Stress and Inflammation as Main Therapeutic Targets

TL;DR: In this article , a review of the benefits of Moringa oleifera leaf extracts in combating the prominent characteristic features of diabetes mellitus is presented, which includes effective control of blood glucose or insulin levels, enhancement of insulin tissue sensitivity, improvement of blood lipid profiles, and protecting against organ damage under sustained conditions of hyperglycemia.
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Functional cereals' anti-diabetic property, phenolic composition, and role on glycemic indices in-vitro.

TL;DR: In this paper , the effects of functional cereals processed and produced from yellow corn, soybean, acha, orange peels and moringa leaves' polyphenolic content, glycemic index, starch composition and their effects on α-amylase and α-glucosidase enzymes in vitro were analyzed.
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“Planeterranea”: An attempt to broaden the beneficial effects of the Mediterranean diet worldwide

TL;DR: This review aimed to collect information about eating habits and native crops in 5 macro-areas (North America, Latin America, Africa, Asia, and Australia) and develop specific “nutritional pyramids” based on the foods available in the macro-area presenting the same nutritional properties and health benefits of Mediterranean Diet.
References
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Journal ArticleDOI

Drug discovery from medicinal plants.

TL;DR: Several compounds from tropical rainforest plant species with potential anticancer activity have been identified and several compounds, mainly from edible plant species or plants used as dietary supplements, that may act as chemopreventive agents are isolated.
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Antioxidant properties of various solvent extracts of total phenolic constituents from three different agroclimatic origins of drumstick tree (Moringa oleifera Lam.) leaves.

TL;DR: In this paper, water, aqueous methanol, and ethanol extracts of freeze-dried leaves of Moringa oleifera Lam. from different agroclimatic regions were examined for radical scavenging capacities and antioxidant activities.
Journal ArticleDOI

Diet and the evolution of human amylase gene copy number variation.

TL;DR: It is found that copy number of the salivary amylase gene (AMY1) is correlated positively with salivaries protein level and that individuals from populations with high-starch diets have, on average, more AMY1 copies than those with traditionally low-st starch diets.
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Inhibition of α-Glucosidase and α-Amylase by Flavonoids

TL;DR: The inhibitory activity of six groups of flav onoids against yeast and rat small intestinal α-glucosidases and porcine pancreatic α-amylase was compared, and chemical structures of flavonoids responsible for the inhibitoryactivity were evaluated.
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Quercetin, a flavonoid antioxidant, prevents and protects streptozotocin-induced oxidative stress and beta-cell damage in rat pancreas.

TL;DR: It is suggested that QE treatment has protective effect in diabetes by decreasing oxidative stress and preservation of pancreatic beta-cell integrity.
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Trending Questions (1)
Is there a related and review literature of malunggay (maringga oleifera) year2021?

The provided paper is a systematic review and meta-analysis on the effect of Moringa oleifera on diabetic hyperglycemia and dyslipidemia in rodent models. It does not mention any related or review literature specifically on Moringa oleifera in the year 2021.