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Open AccessJournal ArticleDOI

Morphometry of human leukocytes

Geert W. Schmid-Schönbein, +2 more
- 01 Nov 1980 - 
- Vol. 56, Iss: 5, pp 866-875
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TLDR
It was shown that all leukocytes, including lymphocytes, have much more membrane area than is needed to cover their volumes, and this membrane area remains constant when the cell is hypotonically swollen.
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This article is published in Blood.The article was published on 1980-11-01 and is currently open access. It has received 297 citations till now.

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Citations
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Leukocyte capillary plugging in myocardial ischemia and reperfusion in the dog.

TL;DR: The results suggest that progressive leukocyte capillary plugging during myocardial ischemia contributes to preventing full restoration of capillary flow upon reperfusion.
Journal ArticleDOI

Apparent viscosity and cortical tension of blood granulocytes determined by micropipet aspiration

TL;DR: The results show that the outer cortex of the cell maintains a small persistent tension which creates a threshold pressure below which the cell will not enter the pipet, and the ratio of cortical flow resistance to flow resistance from the cell interior shows that the cortex does not contribute significantly to the total flow resistance.
Journal ArticleDOI

Mechanical models for living cells--a review

TL;DR: This review of mechanical models developed to characterize mechanical responses of living cells when subjected to both transient and dynamic loads finds that the biphasic model has been widely used to study musculoskeletal cell mechanics.
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Deterministic hydrodynamics: Taking blood apart

TL;DR: This work shows the fractionation of whole blood components and isolation of blood plasma with no dilution by using a continuous-flow deterministic array that separates blood components by their hydrodynamic size, independent of their mass.
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Mechanics of stimulated neutrophils: cell stiffening induces retention in capillaries

TL;DR: Data suggest that neutrophil stiffening may be both necessary and sufficient for the retention that is observed in lung and other capillaries in the acute inflammatory process and may be the result of increased stiffness stimulated by chemoattractants.
References
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Book ChapterDOI

Stereological principles for morphometry in electron microscopic cytology.

TL;DR: This chapter focuses on the stereological principles for morphometry in electron microscopic cytology and the possibilities of applying morphometric methods to correlative cell biology.
Journal ArticleDOI

Techniques for the preservaation of three-dimensional structure in preparing specimens for the electron microscope†

TL;DR: In this paper, a method of sample preparation that reduces distortion and maintains 3D structure is described, where a droplet is placed on a formvar-coated screen and fix with osmic acid vapor.
Journal ArticleDOI

Galloylglucoses of low molecular weight as mordant in electron microscopy. I. Procedure, and evidence for mordanting effect.

TL;DR: Various experimental conditions tested indicate that the LMGG display a complex effect on fixed tissues: they act primarily as a mordant between osmium-treated structures and lead, and concomitantly stabilize some tissue components against extraction incurred during dehydration and subsequent processing.
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