Journal ArticleDOI
Mussel-Inspired Polydopamine Coating as a Universal Route to Hydroxyapatite Crystallization
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TLDR
A universal biomineralization route, called polydopamine‐assisted hydroxyapatite formation (pHAF), that can be applied to virtually any type and morphology of scaffold materials is demonstrated and can be an innovative foundation for future tissue engineering.Abstract:
Bone tissue is a complex biocomposite material with a variety of organic (e.g., proteins, cells) and inorganic (e.g., hydroxyapatite crystals) components hierarchically organized with nano/microscale precision. Based on the understanding of such hierarchical organization of bone tissue and its unique mechanical properties, efforts are being made to mimic these organic–inorganic hybrid biocomposites. A key factor for the successful designing of complex, hybrid biomaterials is the facilitation and control of adhesion at the interfaces, as many current synthetic biomaterials are inert, lacking interfacial bioactivity. In this regard, researchers have focused on controlling the interface by surface modifications, but the development of a simple, unified way to biofunctionalize diverse organic and inorganic materials remains a critical challenge. Here, a universal biomineralization route, called polydopamine-assisted hydroxyapatite formation (pHAF), that can be applied to virtually any type and morphology of scaffold materials is demonstrated. Inspired by the adhesion mechanism of mussels, the pHAF method can readily integrate hydroxyapatites on ceramics, noble metals, semiconductors, and synthetic polymers, irrespective of their size and morphology (e.g., porosity and shape). Surface-anchored catecholamine moieties in polydopamine enriches the interface with calcium ions, facilitating the formation of hydroxyapatite crystals that are aligned to the c-axes, parallel to the polydopamine layer as observed in natural hydroxyapatites in mineralized tissues. This universal surface biomineralization can be an innovative foundation for future tissue engineering.read more
Citations
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Journal ArticleDOI
Polydopamine and Its Derivative Materials: Synthesis and Promising Applications in Energy, Environmental, and Biomedical Fields
Yanlan Liu,Kelong Ai,Lehui Lu +2 more
Journal ArticleDOI
Polydopamine Surface Chemistry: A Decade of Discovery.
TL;DR: The current state of the art in polydopamine coating methods is described, efforts underway to uncover and tailor the complex structure and chemical properties of polyDopamine are described, and emerging trends and needs are identified, including the use of dopamine analogs, nitrogen-free polyphenolic precursors, and improvement of coating mechanical properties.
Journal ArticleDOI
Bioinspired catecholic chemistry for surface modification.
Qian Ye,Feng Zhou,Weimin Liu +2 more
TL;DR: The state-of-the-art research in the area is described: the design and synthesis of catecholic molecules, their adsorption mechanisms and the stability of assemblies in solution, and their applications etc.
Journal ArticleDOI
Non-Covalent Self-Assembly and Covalent Polymerization Co-Contribute to Polydopamine Formation
TL;DR: The study reveals a different perspective of polydopamine formation, where it forms in part by the self‐assembly of dopamine and DHI, providing a new clue toward understanding the structures of catecholamines such as melanin.
Journal ArticleDOI
Antifouling membranes for sustainable water purification: strategies and mechanisms
TL;DR: This review will first introduce the major foulants and the principal mechanisms of membrane fouling, and then highlight the development, current status and future prospects of antifouling membranes, including ant ifouling strategies, preparation techniques and practical applications.
References
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Journal ArticleDOI
Mussel-Inspired Surface Chemistry for Multifunctional Coatings
TL;DR: Inspired by the composition of adhesive proteins in mussels, dopamine self-polymerization is used to form thin, surface-adherent polydopamine films onto a wide range of inorganic and organic materials, including noble metals, oxides, polymers, semiconductors, and ceramics.
Journal ArticleDOI
Ti based biomaterials, the ultimate choice for orthopaedic implants – A review
TL;DR: In this paper, the influence of alloy chemistry, thermomechanical processing and surface condition on these properties is discussed and various surface modification techniques to achieve superior biocompatibility, higher wear and corrosion resistance.
Journal ArticleDOI
Designing materials for biology and medicine
Robert Langer,David A. Tirrell +1 more
TL;DR: New challenges and directions in biomaterials research are discussed, including synthetic replacements for biological tissues, designing materials for specific medical applications, and materials for new applications such as diagnostics and array technologies.
Journal ArticleDOI
THE MATERIAL BONE: Structure-Mechanical Function Relations
S. Weiner,Hanoch Daniel Wagner +1 more
TL;DR: The structure-mechanical relations at each of the hierarchical levels of organization are reviewed, highlighting wherever possible both underlying strategies and gaps in the authors' knowledge.
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