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Neonicotinoid contamination of global surface waters and associated risk to aquatic invertebrates: A review

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TLDR
It appears that environmentally relevant concentrations of neonicotinoids in surface waters worldwide are well within the range where both short- and long-term impacts on aquatic invertebrate species are possible over broad spatial scales.
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This article is published in Environment International.The article was published on 2015-01-01. It has received 873 citations till now.

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Occurrence and removal of organic micropollutants: An overview of the watch list of EU Decision 2015/495

TL;DR: The most commonly used conventional and advanced treatment processes to remove micropollutants are described, as well as the lack of reports concerning some substances of the watch list, the study of un-spiked aquatic matrices and the assessment of transformation by-products.
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Agricultural insecticides threaten surface waters at the global scale.

TL;DR: The data show that more than 50% of detected insecticide concentrations exceed regulatory threshold levels, which indicates that surface water pollution resulting from current agricultural insecticide use constitutes an excessive threat to aquatic biodiversity and suggests the biological integrity of global water resources is at a substantial risk.
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The environmental risks of neonicotinoid pesticides: a review of the evidence post 2013

TL;DR: A growing body of evidence demonstrates that persistent, low levels of neonicotinoids can have negative impacts on a wide range of free-living organisms.
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Are bee diseases linked to pesticides? - A brief review.

TL;DR: While the former are the immediate cause of colony collapses and bee declines, the latter are a key factor contributing to the increasing negative impact of parasitic infections observed in bees in recent decades.
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Effects of Neonicotinoid Pesticide Exposure on Human Health: A Systematic Review.

TL;DR: The studies conducted to date were limited in number with suggestive but methodologically weak findings related to chronic exposure, and more studies are needed to fully understand their effects on human health.
References
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Journal ArticleDOI

Overview of the Status and Global Strategy for Neonicotinoids

TL;DR: The crystal structure of the acetylcholine-binding proteins provides the theoretical foundation for designing homology models of the corresponding receptor ligand binding domains within the nAChRs, a useful basis for virtual screening of chemical libraries and rational design of novel insecticides acting on these practically relevant channels.
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REVIEW: An overview of the environmental risks posed by neonicotinoid insecticides

TL;DR: Major knowledge gaps remain, but current use of neonicotinoids is likely to be impacting on a broad range of non-target taxa including pollinators and soil and aquatic invertebrates and hence threatens a range of ecosystem services.
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Neonicotinoid Pesticide Reduces Bumble Bee Colony Growth and Queen Production

TL;DR: Given the scale of use of neonicotinoid insecticides, it is suggested that they may be having a considerable negative impact on wild bumble bee populations across the developed world.
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A Single P450 Allele Associated with Insecticide Resistance in Drosophila

TL;DR: Microarray analysis of all P450s in Drosophila melanogaster shows that DDT-R, a gene conferring resistance to DDT, is associated with overtranscription of a single cytochrome P450 gene, Cyp6g1, which has spread globally.
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Declines in insectivorous birds are associated with high neonicotinoid concentrations

TL;DR: The hypothesis that the most widely used neonicotinoid insecticide, imidacloprid, has a negative impact on insectivorous bird populations is investigated and it is shown that, in the Netherlands, local population trends were significantly more negative in areas with higher surface-water concentrations of imidcloprid.
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