Journal ArticleDOI
Neuroendocrine and immune system interactions in stress and depression
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This article provides a foundation for integrating neuroendocrine-immune interactions into the formulation of neuropsychiatric and immunologic disease.About:
This article is published in Psychiatric Clinics of North America.The article was published on 1998-06-01. It has received 167 citations till now. The article focuses on the topics: Neuroimmunology & Psychoneuroimmunology.read more
Citations
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Global and regional estimates of violence against women: prevalence and health effects of intimate partner violence and non-partner sexual violence.
Claudia García-Moreno,Christina Pallitto,Karen Devries,Heidi Stöckl,Charlotte Watts,Naeemah Abrahams +5 more
TL;DR: In this article, the authors present the first global systematic review of scientific data on the prevalence of two forms of violence against women: violence by an intimate partner (intimate partner violence) and sexual violence by someone other than a partner.
Journal ArticleDOI
The brain reward circuitry in mood disorders
Scott J. Russo,Eric J. Nestler +1 more
TL;DR: This Review synthesizes recent data from human and rodent studies from which emerges a circuit-level framework for understanding reward deficits in depression, and discusses some of the molecular and cellular underpinnings of this framework, ranging from adaptations in glutamatergic synapses and neurotrophic factors to transcriptional and epigenetic mechanisms.
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Emotions, morbidity, and mortality: new perspectives from psychoneuroimmunology.
TL;DR: It is argued that distress-related immune dysregulation may be one core mechanism behind a large and diverse set of health risks associated with negative emotions, and resources such as close personal relationships that diminish negative emotions enhance health in part through their positive impact on immune and endocrine regulation.
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Cigarette smoking, body mass index, and stressful life events as risk factors for psoriasis: Results from an Italian case-control study
Luigi Naldi,Liliane Chatenoud,Dennis Linder,Anna Belloni Fortina,Andrea Peserico,Anna Virgili,Pier Luigi Bruni,Vito Ingordo,Giovanni Lo Scocco,C Solaroli,Donatella Schena,Annalisa Barba,Anna Di Landro,Enrico Pezzarossa,Fabio Arcangeli,Claudia Gianni,Roberto Betti,Paolo Carli,Alessandro Farris,Gian Franco Barabino,Carlo La Vecchia,Carlo La Vecchia +21 more
TL;DR: Risks of psoriasis of recent onset with smoking habits, body mass index (BMI) and stressful life events were consistent with a multiplicative model of risk combination with no significant statistical interaction.
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Depression and immune function: central pathways to morbidity and mortality.
TL;DR: Evidence suggesting that depression contributes to disease and death through immune dysregulation and direct and indirect processes pose the greatest health risks for older adults who already show age-related increases in proinflammatory cytokine production are reviewed.
References
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TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties.
Tim R. Mosmann,R L Coffman +1 more
TL;DR: Two types of cloned helper T cells are described, defined primarily by differences in the pattern of lymphokines ynthesized, and the different functions of the two types of cells and their lymphokine synthesis are discussed.
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Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
TL;DR: It is shown here that this morphological change is closely associated with excision of nucleosome chains from nuclear chromatin, apparently through activation of an intracellular, but non-lysosomal, endonuclease.
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The acute phase response
Heinz Baumann,Jack Gauldie +1 more
TL;DR: This review outlines the principal cellular and molecular mechanisms that control initiation of the tissue response at the site of injury, the recruitment of the systemic defense mechanisms, the acute phase response of the liver and the resolution of the acutephase response.
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Immunosuppression by Glucocorticoids: Inhibition of NF-κB Activity Through Induction of IκB Synthesis
TL;DR: It is shown that glucocorticoids are potent inhibitors of nuclear factor kappa B activation in mice and cultured cells, mediated by induction of the IκBα inhibitory protein, which traps activated NF-κB in inactive cytoplasmic complexes.
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Effect of psychosocial treatment on survival of patients with metastatic breast cancer
David Spiegel,David Spiegel,HelenaC. Kraemer,HelenaC. Kraemer,JoanR. Bloom,JoanR. Bloom,Ellen Gottheil,Ellen Gottheil +7 more
TL;DR: The effect of psychosocial intervention on time of survival of 86 patients with metastatic breast cancer was studied prospectively and survival plots indicated that divergence in survival began at 20 months after entry, or 8 months after intervention ended.