Journal ArticleDOI
New advances in the study on the interaction of [Cr(phen)2(dppz)]3+ complex with biological models; association to transporting proteins.
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TLDR
Experimental results suggests that [Cr(phen)(2)(dppz)](3+) binds to serum albumins, by which these proteins could act as carriers of this complex for further applications in PDT.About:
This article is published in Journal of Inorganic Biochemistry.The article was published on 2011-05-01. It has received 66 citations till now.read more
Citations
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Journal ArticleDOI
Affinity of rosmarinic acid to human serum albumin and its effect on protein conformation stability.
TL;DR: The interaction between RA and human serum albumin (HSA) was investigated by multi-spectroscopic, electrochemistry, molecular docking and molecular dynamics simulation methods, and it was suggested that RA was bound to HSA with moderately strong binding affinity through hydrophobic interaction.
Journal ArticleDOI
DNA- and BSA-binding studies and anticancer activity against human breast cancer cells (MCF-7) of the zinc(II) complex coordinated by 5,6-diphenyl-3-(2-pyridyl)-1,2,4-triazine.
TL;DR: The results indicate that the parent complex displays cytotoxicity against human breast cancer cell lines (MCF-7) with an IC50 value of 10.44μM, remarkable that the complex can introduce as a potential anticancer drug.
Journal ArticleDOI
DNA binding, DNA cleavage and BSA interaction of a mixed-ligand copper(II) complex with taurine Schiff base and 1,10-phenanthroline.
TL;DR: Results showed that the Cu(II) complex could quench the intrinsic fluorescence of bovine serum albumin (BSA) remarkably through a static quenching process, and induce a conformational change with the loss of helical stability of protein.
Journal ArticleDOI
BSA binding and antimicrobial studies of branched polyethyleneimine-copper(II)bipyridine/phenanthroline complexes.
TL;DR: The interaction of two water soluble branched polyethyleneimine-copper(II) complexes containing bipyridine/phenanthroline with bovine serum albumin (BSA) was studied by UV-Visible absorption, fluorescence, lifetime measurements and circular dichroism spectroscopic techniques.
Journal ArticleDOI
A mononuclear Cu(II) complex with 5,6-diphenyl-3-(2-pyridyl)-1,2,4-triazine: Synthesis, crystal structure, DNA- and BSA-binding, molecular modeling, and anticancer activity against MCF-7, A-549, and HT-29 cell lines
Marzieh Anjomshoa,Hassan Hadadzadeh,Masoud Torkzadeh-Mahani,Seyed Jamilaldin Fatemi,Mahboubeh Adeli-Sardou,Hadi Amiri Rudbari,Viviana Mollica Nardo +6 more
TL;DR: The in vitro cytotoxicity indicate that the copper(II) complex has excellent anticancer activity against the three human carcinoma cell lines, MCF-7, A-549, and HT-29, with IC50 values of 9.8, 7.80, and 4.50 μM.
References
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Book
Principles of fluorescence spectroscopy
TL;DR: This book describes the fundamental aspects of fluorescence, the biochemical applications of this methodology, and the instrumentation used in fluorescence spectroscopy.
Journal ArticleDOI
Thermodynamics of protein association reactions: forces contributing to stability
Philip D. Ross,S. Subramanian +1 more
TL;DR: On the basis of the thermochemical behavior of small molecule interactions, it is concluded that the strengthening of hydrogen bonds in the past decade, a complete thermodynamic description of the self-association of many proteins and their interactions is concluded.
BookDOI
Molecular fluorescence : principles and applications
TL;DR: In this article, the effects of intermolecular photophysical processes on fluorescence emission are discussed and an analysis of the effect of polarity of fluorescence emissions is presented.
Journal ArticleDOI
Atomic structure and chemistry of human serum albumin.
Xiao Min He,Daniel C. Carter +1 more
TL;DR: The three-dimensional structure of human serum albumin has been determined crystallographically to a resolution of 2.8 Å and should provide insight into future pharmacokinetic and genetically engineered therapeutic applications of serumalbumin.
Book ChapterDOI
Structure of serum albumin.
Daniel C. Carter,Joseph X. Ho +1 more
TL;DR: This chapter provides an insight of the findings of past significant papers with the current knowledge of the recently determined high resolution X-ray structure of serum albumin and suggests that AFP may have a higher affinity for some unknown ligands important for fetal development.
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Thermodynamics of protein association reactions: forces contributing to stability
Philip D. Ross,S. Subramanian +1 more