Journal ArticleDOI
New aspects about Crimean-Congo hemorrhagic fever (CCHF) cases and associated fatality trends: A global systematic review and meta-analysis.
TLDR
The study results confirm that an apparent increasing CCHF cases occurred through the past decades and the trends of annually and periodically C CHF cases and fatality rates were also increased.Abstract:
Crimean-Congo hemorrhagic fever (CCHF) is the most popular tick-borne disease causing by Crimean-Congo hemorrhagic fever virus (CCHFV). There are several valuable reviews considering some fields of the CCHF aspects. While there is no a systematic review about means and trends of CCHF cases and fatality rate, means and trends of CCHF cases and fatality rates of human occupations involved in CCHF. Therefore, this meta-analysis review performed to highlight and provide a global detailed of the above CCHF aspects. Among 398 collected papers, 173 papers were become this meta-analysis review. The study results confirm that an apparent increasing CCHF cases occurred through the past decades. The trends of annually and periodically CCHF cases and fatality rates were also increased. The means of annually and periodically CCHF cases and fatality rates were 57 and 432 cases, and 10 cases and 32.2 % and 49 cases and 28.8 %, respectively. The means of annually and periodically CCHF fatality rates are about one-tenth of CCHF human cases. The mean of CCHF fatality rates in Africa (22.0 %) is lower than Asia (33.5 %) and Europe (33.8 %). Among occupations involved in CCHF, agricultural (28.9 %), health-care (19.2 %) and slaughterhouse (16.7 %) workers, and farmers (13.9 %) had the maximum CCHF fatality rates in order. Based on literature review of CCHFV S-segment aspects, several clades and genotypes are reported to distribute in Africa, Asia and Europe regions. There are very wide fields to investigate the epidemiology characteristics of CCHFV clades, genotypes and their distribution in the future.read more
Citations
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Journal ArticleDOI
Worldwide epidemiology of Crimean-Congo Hemorrhagic Fever Virus in humans, ticks and other animal species, a systematic review and meta-analysis.
Jean Thierry Ebogo Belobo,Sebastien Kenmoe,Cyprien Kengne-Nde,Cynthia Paola Demeni Emoh,Arnol Bowo-Ngandji,Serges Tchatchouang,Jocelyne Noel Sowe Wobessi,Chris Andre Mbongue Mikangue,Hervé Raoul Tazokong,Sandrine Rachel Kingue Bebey,Efietngab Atembeh Noura,Aude Christelle Ka'e,Raïssa Estelle Guiamdjo Simo,Abdou Fatawou Modiyinji,Dimitri Tchami Ngongang,Emmanuel Che,Sorel Kenfack,Nathalie Diane Nzukui,Nathalie Amvongo Adjia,Isabelle Tatiana Babassagana,Gadji Mahamat,Donatien Serge Mbaga,Wilfred Fon Mbacham,Serge Alain Sadeuh-Mbah,Richard Njouom +24 more
TL;DR: In this article, the global case fatality rate (CFR) of CCHFV infections and the prevalence of cases in humans, ticks and other animal species were estimated.
Journal ArticleDOI
Crimean-Congo Hemorrhagic Fever Virus (CCHFV): A Silent but Widespread Threat.
TL;DR: A review of recent research and articles on the complicated relationship between virus, vector, and host and how biosurveillance at each level informs disease spread and risk is presented in this article.
Journal ArticleDOI
Nucleoside-Modified mRNA Vaccines Protect IFNAR <sup>–/–</sup> Mice against Crimean-Congo Hemorrhagic Fever Virus Infection
TL;DR: In this paper , the authors demonstrate that vaccination with nucleoside-modified mRNA-lipid nanoparticles (mRNA-LNP) can protect IFNAR-/- mice against lethal CCHFV infection.
Journal ArticleDOI
Development of a protective inactivated vaccine against Crimean-Congo hemorrhagic fever infection.
TL;DR: In this article, the authors evaluated the development, immunogenicity, and immune response durations for cell-culture-derived inactivated vaccine (CCVax) formulations in comparison with those of mouse-brain-derived vaccine (MBVax), and showed that CCVax formulations induced higher IgG and neutralizing Ab titers at all the measured time points.
Journal ArticleDOI
New insights about human tick infestation features: a systematic review and meta-analysis
Hamid Kassiri,Hassan Nasirian +1 more
TL;DR: In this article, the authors performed a meta-analysis about the global ranks of tick infestation rates and records, global monthly tick bites and annually and periodically trends of the tick infestation rates, and the global tick rates among years, mounts, regions, and countries.
References
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Journal ArticleDOI
Crimean-Congo haemorrhagic fever
TL;DR: Crimean-Congo haemorrhagic fever (CCHF) is an often fatal viral infection described in about 30 countries, and it has the most extensive geographic distribution of the medically important tickborne viral diseases, closely approximating the known global distribution of Hyalomma spp ticks.
Journal ArticleDOI
The epidemiology of tick-borne Crimean-Congo hemorrhagic fever in Asia, Europe, and Africa.
TL;DR: It was only in 1967, when Soviet workers first used the generally accepted newborn white mouse inoculation technique for CCHF virus isolation and study, that the etiologic agent could be characterized antigenically, physiochemically, and morphologically.
Journal ArticleDOI
Changes to taxonomy and the International Code of Virus Classification and Nomenclature ratified by the International Committee on Taxonomy of Viruses (2017)
Andrew M. Q. King,Elliot J. Lefkowitz,Arcady Mushegian,Michael J. Adams,Bas E. Dutilh,Bas E. Dutilh,Alexander E. Gorbalenya,Alexander E. Gorbalenya,Balázs Harrach,Robert L. Harrison,Sandra Junglen,Nick J. Knowles,Andrew M. Kropinski,Mart Krupovic,Jens H. Kuhn,Max L. Nibert,Luisa Rubino,Sead Sabanadzovic,Hélène Sanfaçon,Stuart G. Siddell,Peter Simmonds,Arvind Varsani,Francisco Murilo Zerbini,Andrew J. Davison +23 more
TL;DR: In this paper, the changes to virus taxonomy approved and ratified by the International Committee on Taxonomy of Viruses (ICTV) in March 2017 are presented, and the changes are described in detail.
Journal ArticleDOI
Crimean-Congo hemorrhagic fever: history, epidemiology, pathogenesis, clinical syndrome and genetic diversity.
Dennis A. Bente,Naomi L. Forrester,Douglas M. Watts,Alexander J. McAuley,Chris A. Whitehouse,Mike Bray +5 more
TL;DR: Current knowledge of CCHFV is summarized, summarizing its molecular biology, maintenance and transmission, epidemiology and geographic range, including an extensive discussion of C CHFV genetic diversity, including maps of the range of the virus with superimposed phylogenetic trees.
Journal ArticleDOI
The epidemiology of Crimean-Congo hemorrhagic fever in Turkey, 2002–2007
Gül Ruhsar Yilmaz,Turan Buzgan,Hasan Irmak,A Safran,Ramazan Uzun,Mustafa Aydın Çevik,M A Torunoglu +6 more
TL;DR: CCHF appears to be a seasonal problem in the Mid-Eastern Anatolia region of Turkey and the possible risk factors for transmission and the clinical and laboratory findings of patients with a diagnosis of CCHF were found to be similar to those reported in the literature.