Journal ArticleDOI
Nitroglycerin improves the hemodynamic response to vasopressin in portal hypertension
Roberto J. Groszmann,David Kravetz,David Kravetz,David Kravetz,Jaime Bosch,Jaime Bosch,Jaime Bosch,Mortom Glickman,Mortom Glickman,Mortom Glickman,Jordi Bruix,Jordi Bruix,Jordi Bruix,James E. Bredfeldt,James E. Bredfeldt,James E. Bredfeldt,Harold O. Conn,Harold O. Conn,Harold O. Conn,Juan Rodes,Juan Rodes,Juan Rodes,Edward H. Storer,Edward H. Storer,Edward H. Storer +24 more
TLDR
Investigation of the effect of nitroglycerin on splanchnic and systemic hemodynamics in cirrhotic patients and portal hypertensive dogs and in dogs provides evidence that the addition of nitreglycerin to an i.v. infusion of vasopressin reversed the detrimental effects of vasipressin while preserving the beneficial effects.About:
This article is published in Hepatology.The article was published on 1982-11-01. It has received 221 citations till now. The article focuses on the topics: Portal venous pressure & Portal hypertension.read more
Citations
More filters
Journal ArticleDOI
Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis
Guadalupe Garcia-Tsao,Arun J. Sanyal,Norman D. Grace,William D. Carey,Margaret C. Shuhart,Gary L. Davis,Kiran Bambha,Andrés Cárdenas,Stanley Martin Cohen,Timothy J. Davern,Steven L. Flamm,Steven B. Han,Charles D. Howell,David R. Nelson,K. Rajender Reddy,Bruce A. Runyon,John B. Wong,Colina Yim,Nizar N. Zein,John M. Inadomi,Darren Baroni,David I. Bernstein,William R. Brugge,Lin Chang,William D. Chey,John T. Cunningham,Kenneth R. DeVault,Steven A. Edmundowicz,Ronnie Fass,Kelvin Hornbuckle,Costas Kefalas,Timothy R. Koch,Jenifer K. Lehrer,Anthony Lembo,John O'Brien,John Papp,Henry P. Parkman,Albert Roach,Richard E. Sampliner,Amnon Sonnenberg,Subbaramiah Sridhar,Miguel A. Valdovinos,John J. Vargo,Marcelo F. Vela,Nizar N. Zein +44 more
TL;DR: Prevention and Management of Gastroesophageal Varices and Variceal Hemorrhage in Cirrhosis Guadalupe Garcia-Tsao, M.D., co-authors.
Journal ArticleDOI
Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis.
Guadalupe Garcia-Tsao,Arun J. Sanyal,Norman D. Grace,William D. Carey,Margaret C. Shuhart,Gary L. Davis,Kiran Bambha,Andrés Cárdenas,Stanley Martin Cohen,Timothy J. Davern,Steven L. Flamm,Steven B. Han,Charles D. Howell,David R. Nelson,K. Rajender Reddy,Bruce A. Runyon,John B. Wong,Colina Yim,Nizar N. Zein,John M. Inadomi,Darren Baroni,David I. Bernstein,William R. Brugge,Lin Chang,William D. Chey,John T. Cunningham,Kenneth R. DeVault,Steven A. Edmundowicz,Ronnie Fass,Kelvin Hornbuckle,Costas Kefalas,Timothy R. Koch,Jenifer K. Lehrer,Anthony Lembo,John O'Brien,John Papp,Henry P. Parkman,Albert Roach,Richard E. Sampliner,Amnon Sonnenberg,Subbaramiah Sridhar,Miguel A. Valdovinos,John J. Vargo,Marcelo F. Vela,Nizar N. Zein +44 more
TL;DR: Prevention and Management of Gastroesophageal Varices and Variceal Hemorrhage in Cirrhosis Guadalupe Garcia-Tsao, M.D., co-authors.
Journal ArticleDOI
The treatment of portal hypertension: A meta-analytic review
Journal ArticleDOI
UK guidelines on the management of variceal haemorrhage in cirrhotic patients
Dhiraj Tripathi,Adrian J. Stanley,Peter C. Hayes,David Patch,Charles Millson,Homoyon Mehrzad,Andrew Austin,James Ferguson,Simon Olliff,Mark Hudson,John M. Christie +10 more
TL;DR: These updated guidelines on the management of variceal haemorrhage have been commissioned by the Clinical Services and Standards Committee (CSSC) of the British Society of Gastroenterology (BSG) under the auspices of the liver section of the BSG.
Journal ArticleDOI
Complications of cirrhosis. I. Portal hypertension
TL;DR: Recent studies suggest that early measurement of HVPG during variceal bleeding may be used as a guide for therapeutic decisions in the treatment of patients with acute varices, and the efficacy of more aggressive techniques should be further tested against beta-blockers in patients with a high risk of bleeding.
References
More filters
Journal ArticleDOI
Effects of somatostatin on hepatic and systemic hemodynamics in patients with cirrhosis of the liver: Comparison with vasopressin
TL;DR: It is shown that somatostatin effectively reduces hepatic blood flow and portal pressure in patients with cirrhosis and severe portal hypertension, without altering the systemic circulation.
Journal ArticleDOI
Wedged and free hepatic venous pressure measured with a balloon catheter
Roberto J. Groszmann,Roberto J. Groszmann,Morton G. Glickman,Morton G. Glickman,AT Blei,AT Blei,Edward H. Storer,Edward H. Storer,Harold O. Conn,Harold O. Conn +9 more
TL;DR: The balloon technique offers many advantages over the conventional approach, including the ease of achieving and demonstrating the wedged position from the femoral approach, the ability to measure the free and wedged pressure repeatedly without manipulating the catheter, and the measurement of pressure in a larger, more representative segment of the liver.
Journal ArticleDOI
Intraarterial Vasopressin in the Treatment of Upper Gastrointestinal Hemorrhage: A Prospective, Controlled Clinical Trial
Harold O. Conn,Harold O. Conn,Gale R. Ramsby,Gale R. Ramsby,Edward H. Storer,Edward H. Storer,Milton G. Mutchnick,Milton G. Mutchnick,Prakash H. Joshi,Prakash H. Joshi,Michael M. Phillips,Michael M. Phillips,George A. Cohen,George A. Cohen,Gary N. Fields,Gary N. Fields,Donald Petroski,Donald Petroski +17 more
TL;DR: The failure of cessation of hemorrhage to improve survival is thought to be due to the degree of advancement of the underlying disease, to the torrential nature of the hemorrhage, and to the use of intraarterial vasopressin in some patients in the conventional treatment group in whom conventional therapy had failed.
Journal ArticleDOI
Measurement of portal pressure and its clinical application
TL;DR: It is still uncertain whether portal pressure is useful in predicting variceal bleeding, but two groups of investigators have recently shown that wedged hepatic vein pressure and portal vein pressure are essentially identical in alcoholic liver disease and probably in cryptogenic cirrhosis and chronic active hepatitis.
Journal ArticleDOI
Effect of intravenously administered posterior pituitary extract on hemorrhage from bleeding esophageal varices. A controlled evaluation.
TL;DR: A controlled study of pituitary extract in patients with cirrhosis and the effects of both esophageal balloon tamponade and emergency surgery in these patients have inherent dangers and are not always effective.