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Noninvasive ventilation to prevent respiratory failure after extubation in high-risk patients

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TLDR
NIV was more effective than SMT in preventing postextubation respiratory failure in a population considered at risk of developing this complication and resulted in a reduction of risk of intensive care unit mortality.
Abstract
Objective:Compared with standard medical therapy (SMT), noninvasive ventilation (NIV) does not reduce the need for reintubation in unselected patients who develop respiratory failure after extubation. The goal of this study was to assess whether early application of NIV, immediately after extubation

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Citations
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Journal ArticleDOI

Non-invasive ventilation in acute respiratory failure

TL;DR: Non-invasive mechanical ventilation has been increasingly used to avoid or serve as an alternative to intubation and in some instances with invasive mechanical ventilation, it improves survival and reduces complications in selected patients with acute respiratory failure.
Journal ArticleDOI

Nasal high-flow versus Venturi mask oxygen therapy after extubation. Effects on oxygenation, comfort, and clinical outcome

TL;DR: Compared with the Venturi mask, NHF results in better oxygenation for the same set FiO2 after extubation, and use of NHF is associated with better comfort, fewer desaturations and interface displacements, and a lower reintubation rate.
References
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Journal ArticleDOI

A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study

J R Le Gall, +2 more
- 22 Dec 1993 - 
TL;DR: The SAPS II, based on a large international sample of patients, provides an estimate of the risk of death without having to specify a primary diagnosis, and is a starting point for future evaluation of the efficiency of intensive care units.
Journal ArticleDOI

Group sequential methods in the design and analysis of clinical trials

TL;DR: In this article, a group sequential design is proposed to divide patient entry into a number of equal-sized groups so that the decision to stop the trial or continue is based on repeated significance tests of the accumulated data after each group is evaluated.
Journal ArticleDOI

A comparison of four methods of weaning patients from mechanical ventilation. Spanish Lung Failure Collaborative Group.

TL;DR: A prospective, randomized, multicenter study involving 546 patients who had received mechanical ventilation for a mean of 7.5±6.1 days and who were considered by their physicians to be ready for weaning, randomly assigned to undergo one of four weaning techniques.
Journal ArticleDOI

Evidence-Based Guidelines for Weaning and Discontinuing Ventilatory Support*

TL;DR: The Discontinuing Ventilatory Support : A Evidence-Based Guidelines for Weaning and http://chestjournal.org services can be found online on the World Wide Web at: The online version of this article, along with updated information and ).
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