Nonpharmacological therapies in Alzheimer's disease: a systematic review of efficacy
Javier Olazarán,Barry Reisberg,Linda Clare,Isabel Cruz,Jordi Peña-Casanova,Teodoro Del Ser,Bob Woods,Cornelia Beck,Stefanie Auer,Claudia K.Y. Lai,Aimee Spector,Sam Fazio,John Bond,Miia Kivipelto,Henry Brodaty,José Manuel Rojo,Helen Collins,Linda Teri,Mary S. Mittelman,Martin Orrell,Howard Feldman,Ruben Muñiz +21 more
TLDR
NPTs emerge as a useful, versatile and potentially cost-effective approach to improve outcomes and QoL in ADRD for both the PWD and CG.Abstract:
Introduction: Nonpharmacological therapies (NPTs) can improve the quality of life (QoL) of people with Alzheimer’s disease (AD) and their carers. The objective of this study was to evaluate the best evidence on the effects of NPTs in AD and related disorders (ADRD) by performing a systematic review and meta-analysis of the entire field. Methods: Existing reviews and major electronic databases were searched for randomized controlled trials (RCTs). The deadline for study inclusion was September 15, 2008. Intervention categories and outcome domains were predefined by consensus. Two researchers working together detected 1,313 candidate studies of which 179 RCTs belonging to 26 intervention categories were selected. Cognitive deterioration had to be documented in all participants, and degenerative etiologyread more
Citations
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2013 Alzheimer's disease facts and figures
William Thies,Laura Bleiler +1 more
TL;DR: This report provides information to increase understanding of the public health impact of Alzheimer's disease (AD), including incidence and prevalence, mortality rates, health expenditures and costs of care, and effect on caregivers and society in general.
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The burden of disease in older people and implications for health policy and practice
Martin Prince,Fan Wu,Yanfei Guo,Luis Miguel Francisco Gutierrez Robledo,Martin O'Donnell,Richard Sullivan,Salim Yusuf +6 more
TL;DR: The authors in this article found that 30.23% of the total global burden of disease is attributable to disorders in people aged 60 years and older, and the leading contributors to disease burden in older people are cardiovascular diseases, malignant neoplasms (15·1%), chronic respiratory diseases (9·5%), musculoskeletal diseases (7·5), and neurological and mental disorders (6·6%).
Journal ArticleDOI
Cognitive stimulation to improve cognitive functioning in people with dementia
TL;DR: There was consistent evidence from multiple trials that cognitive stimulation programmes benefit cognition in people with mild to moderate dementia over and above any medication effects.
Dementia: a public health priority
TL;DR: In this article, a nadalje svakodnevno raditi na prevenciji demencije, osiguravati resurse and osmisljavati strategije borbe protiv demence, to ocekivati pozitivnih pomaka, kako na podrucju terapije, rane dijagnostike, tako i na podrugju rehabilitacije osoba s demencjom.
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Cognitive Stimulation in Patients with Dementia: Randomized Controlled Trial
TL;DR: The results suggest that a cognitive stimulation treatment for PWDs would improve not only their cognition, but also behavioral symptoms.
References
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