T
Teodoro Del Ser
Researcher at Carlos III Health Institute
Publications - 58
Citations - 6608
Teodoro Del Ser is an academic researcher from Carlos III Health Institute. The author has contributed to research in topics: Dementia & Cognitive decline. The author has an hindex of 28, co-authored 50 publications receiving 5494 citations. Previous affiliations of Teodoro Del Ser include Autonomous University of Madrid.
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Journal ArticleDOI
Efficacy of rivastigmine in dementia with Lewy bodies: A randomised, double-blind, placebo-controlled international study
Ian G. McKeith,Teodoro Del Ser,PierFranco Spano,Murat Emre,Keith Wesnes,Ravi Anand,Ana Cicin-Sain,Roberto Ferrara,René Spiegel +8 more
TL;DR: Rivastigmine 6-12 mg daily produces statistically and clinically significant behavioural effects in patients with Lewy-body dementia, and seems safe and well tolerated if titrated individually.
Journal ArticleDOI
Nonpharmacological therapies in Alzheimer's disease: a systematic review of efficacy
Javier Olazarán,Barry Reisberg,Linda Clare,Isabel Cruz,Jordi Peña-Casanova,Teodoro Del Ser,Bob Woods,Cornelia Beck,Stefanie Auer,Claudia K.Y. Lai,Aimee Spector,Sam Fazio,John Bond,Miia Kivipelto,Henry Brodaty,José Manuel Rojo,Helen Collins,Linda Teri,Mary S. Mittelman,Martin Orrell,Howard Feldman,Ruben Muñiz +21 more
TL;DR: NPTs emerge as a useful, versatile and potentially cost-effective approach to improve outcomes and QoL in ADRD for both the PWD and CG.
Journal ArticleDOI
Social Networks, Social Integration, and Social Engagement Determine Cognitive Decline in Community-Dwelling Spanish Older Adults
TL;DR: It is indicated that few social ties, poor integration, and social disengagement are risk factors for cognitive decline among community-dwelling elderly persons.
Journal ArticleDOI
New insights into the genetic etiology of Alzheimer’s disease and related dementias
Céline Bellenguez,Fahri Küçükali,Iris E. Jansen,Luca Kleineidam,Sonia Moreno-Grau,Najaf Amin,Adam C. Naj,R. Campos-Martín,Benjamin Grenier-Boley,Víctor Andrade,Peter Holmans,Anne Boland,Vincent Damotte,S. J. van der Lee,Marcos R. Costa,Teemu Kuulasmaa,Qiong Yang,Itziar de Rojas,Joshua C. Bis,Amber Yaqub,Ivana Prokic,Julien Chapuis,Shahzad Ahmad,Vilmantas Giedraitis,Dag Aarsland,Carla Abdelnour,Emilio Alarcón-Martín,Daniel Alcolea,Montserrat Alegret,Ignacio Alvarez,Victoria Alvarez,Nicola J. Armstrong,Anthoula Tsolaki,Carmen Antúnez,Ildebrando Appollonio,Marina Arcaro,Silvana Archetti,Alfonso Arias Pastor,Beatrice Arosio,Lavinia Athanasiu,Henri Bailly,Nerisa Banaj,Miquel Baquero,Sandra Barral,Alexa S. Beiser,Ana Pastor,Jennifer E. Below,Penny Benchek,Luisa Benussi,Claudine Berr,Céline Besse,Valentina Bessi,Giuliano Binetti,Alessandra Bizarro,Rafael Blesa,Mercè Boada,Eric Boerwinkle,S. Borroni,Silvia Boschi,Paola Bossù,Geir Bråthen,Jan Bressler,Catherine Bresner,Henry Brodaty,Keeley J. Brookes,Luis I. Brusco,Dolores Buiza-Rueda,Katharina Bürger,Vanessa Burholt,William S. Bush,Miguel Calero,Laura B. Cantwell,Geneviève Chêne,Jaeyoon Chung,Michael L. Cuccaro,Angel Carracedo,Roberta Cecchetti,Laura Cervera-Carles,Camille Charbonnier,Hung-Hsin Chen,Caterina Chillotti,Simona Ciccone,Jurgen A.H.R. Claassen,Christopher M. Clark,Elisa Conti,Anaïs Corma-Gómez,Emanuele Maria Costantini,Carlo Custodero,D. Daian,Maria Carolina Dalmasso,Antonio Daniele,Efthimios Dardiotis,Jean-François Dartigues,Peter Paul De Deyn,Katia de Paiva Lopes,Lot de Witte,Stéphanie Debette,Jürgen Deckert,Teodoro Del Ser,Nicola Denning,Anita L. DeStefano,Martin Dichgans,Janine Diehl-Schmid,Monica Diez-Fairen,Paolo Rosso,Srdjan Djurovic,Emmanuelle Duron,Emrah Düzel,Carole Dufouil,Gudny Eiriksdottir,Sebastiaan Engelborghs,Valentina Escott-Price,Ana Espinosa,Michael Ewers,Kelley Faber,Tagliavini Fabrizio,Sune F. Nielsen,David W. Fardo,Lucia Farotti,Chiara Fenoglio,Marta Fernández-Fuertes,Raffaele Ferrari,Catarina Beatriz Silva Ferreira,Evelyn Ferri,Bertrand Fin,Peter Fischer,Tormod Fladby,Klaus Fliessbach,Bernard Fongang,Myriam Fornage,Juan Fortea,Tatiana Foroud,Silvia Fostinelli,Nick C. Fox,Emilio Franco-Macías,María J. Bullido,Ana Frank-García,Lutz Froelich,Brian Fulton-Howard,Daniela Galimberti,José María García-Alberca,Pablo Garcia-Gonzalez,Sebastián García-Madrona,Guillermo García-Ribas,Roberta Ghidoni,Ina Giegling,Giaccone Giorgio,Alison Goate,Oliver Goldhardt,Duber Gomez-Fonseca,Antonio González-Pérez,Caroline Graff,Giulia Grande,Emma Green,Timo Grimmer,Edna Grünblatt,Michelle Grunin,Vilmundur Gudnason,Tamar Guetta-Baranes,Annakaisa Haapasalo,Georgios M. Hadjigeorgiou,Jonathan L. Haines,Kara L. Hamilton-Nelson,Harald Hampel,Olivier Hanon,John Hardy,T. Hartmann,Lucrezia Hausner,Janet C Harwood,Stefanie Heilmann-Heimbach,Seppo Helisalmi,Michael T. Heneka,Isabel Hernández,Martin J. Herrmann,Per Hoffmann,Clive Holmes,Henne Holstege,Raquel Huerto Vilas,Marc Hulsman,Jack Humphrey,Geert Jan Biessels,Xueqiu Jian,Charlotte Johansson,Gyungah Jun,Y. Kastumata,John S. K. Kauwe,Patrick G. Kehoe,Lena Kilander,Anne Kinhult Ståhlbom,Miia Kivipelto,Anne M. Koivisto,Johannes Kornhuber,Mary H. Kosmidis,Walter A. Kukull,Pavel P. Kuksa,Brian W. Kunkle,Amanda B. Kuzma,Carmen Lage,Erika J. Laukka,Lenore J. Launer,Alessandra Lauria,Chien‐Yueh Lee,Jenni Lehtisalo,Ondrej Lerch,Alberto Lleó,W. T. Longstreth,Oscar L. Lopez,Adolfo López de Munain,Seth Love,Malin Löwemark,L. Luckcuck,Kathryn L. Lunetta,Yiyi Ma,Juan Macías,Catherine A. MacLeod,Wolfgang Mader,Francesca Mangialasche,Marco Spallazzi,Marta Marquié,Rachel Marshall,Eden R. Martin,Angel Martin Montes,Carmen Martinez Rodriguez,Carlo Masullo,Richard Mayeux,Simon Head,Patrizia Mecocci,Miguel Medina,Alun Meggy,Shima Mehrabian,Silvia Mendoza,Manuel Menéndez-González,Pablo Mir,Susanne Moebus,Merel O. Mol,Laura Molina-Porcel,Laura Montrreal,Laura Morelli,Fermin Moreno,Kevin Morgan,Thomas H. Mosley,Markus M. Nöthen,Carolina Muchnik,Shubhabrata Mukherjee,Benedetta Nacmias,Tiia Ngandu,Gaël Nicolas,Børge G. Nordestgaard,Robert Olaso,Adelina Orellana,Michela Orsini,G. Ortega,Alessandro Padovani,Caffarra Paolo,Goran Papenberg,Lucilla Parnetti,Florence Pasquier,Pau Pastor,Gina M. Peloso,Alba Pérez-Cordón,Jordi Pérez-Tur,Pierre Pericard,Oliver Peters,Yolande A.L. Pijnenburg,Juan A. Pineda,Gerard Piñol-Ripoll,Claudia Pisanu,Thomas Polak,Julius Popp,Danielle Posthuma,Josef Priller,Raquel Delgado Puerta,Olivier Quenez,Inés Quintela,Jesper Qvist Thomassen,Alberto Rábano,Innocenzo Rainero,Farid Rajabli,Inez H.G.B. Ramakers,Luis Miguel Real,Marcel J. T. Reinders,Christiane Reitz,Dolly Reyes-Dumeyer,Perry G. Ridge,Steffi G. Riedel-Heller,Peter Riederer,Natalia Roberto,Eloy Rodríguez-Rodríguez,Arvid Rongve,I. Allende,Maitée Rosende-Roca,Jose Luis Royo,Elisa Rubino,Dan Rujescu,María Eugenia Sáez,Paraskevi Sakka,Ingvild Saltvedt,Angela Sanabria,M B Sánchez-Arjona,Florentino Sanchez-Garcia,Pascual Sanchez Juan,Raquel Sánchez-Valle,Sigrid Botne Sando,Chloé Sarnowski,Claudia L. Satizabal,Michela Scamosci,Nikolaos Scarmeas,Elio Scarpini,Philip Scheltens,Norbert Scherbaum,Martin Scherer,Matthias Schmid,Anja Schneider,Jonathan M. Schott,Geir Selbæk,Davide Seripa,Manuel Serrano,Jin Sha,Alexey A. Shadrin,Olivia Anna Skrobot,Susan Slifer,G. Snijders,Hilkka Soininen,Vincenzo Solfrizzi,Alina Solomon,Yeunjoo E. Song,Sandro Sorbi,Oscar Sotolongo-Grau,Gianfranco Spalletta,Annika Spottke,Alessio Squassina,Eystein Stordal,Juan Pablo Tartan,Lluís Tárraga,Niccolò Tesi,Anbupalam Thalamuthu,Tegos Thomas,Giuseppe Tosto,Latchezar Traykov,Lucio Tremolizzo,Anne Tybjærg-Hansen,André G. Uitterlinden,Abbe Ullgren,Ingun Ulstein,Sergi Valero,Otto Valladares,Christine Van Broeckhoven,Jeffery M. Vance,Badri N. Vardarajan,Aad Van Der Lugt,Jasper Van Dongen,Jeroen van Rooij,John C. van Swieten,Rik Vandenberghe,Frans R.J. Verhey,Jean-Sébastien Vidal,Jonathan Vogelgsang,Martin Vyhnalek,Michael Wagner,David Wallon,Li-San Wang,Ruiqi Wang,Leonie Weinhold,Jens Wiltfang,Gill Windle,Bob Woods,Mary Yannakoulia,Habil Zare,Yi Zhao,Xiaoling Zhang,Congcong Zhu,Miren Zulaica,Lindsay A. Farrer,Bruce M. Psaty,Mohsen Ghanbari,Towfique Raj,Perminder S. Sachdev,Karen A. Mather,Frank Jessen,M. Arfan Ikram,Alexandre de Mendonça,Jakub Hort,Magda Tsolaki,Margaret A. Pericak-Vance,Philippe Amouyel,Julie Williams,Ruth Frikke-Schmidt,Jordi Clarimón,Jean-François Deleuze,Giacomina Rossi,Sudha Seshadri,Ole A. Andreassen,Martin Ingelsson,Mikko Hiltunen,Kristel Sleegers,Gerard D. Schellenberg,Cornelia M. van Duijn,Rebecca Sims,Wiesje M. van der Flier,Agustín Ruiz,Alfredo Ramirez,Jean-Charles Lambert +401 more
TL;DR: This paper performed a two-stage genome-wide association study with 111,326 clinically diagnosed/proxy AD cases and 677,663 controls and found 75 risk loci, of which 42 were new at the time of analysis.
Journal ArticleDOI
A Phase II Trial of Tideglusib in Alzheimer's Disease
Simon Lovestone,Mercè Boada,Bruno Dubois,Michael Hüll,Juha O. Rinne,Hans-Jürgen Huppertz,Miguel Calero,María V. Andrés,Belén Gómez-Carrillo,Teresa Leon,Teodoro Del Ser +10 more
TL;DR: Short term tideglusib was acceptably safe but produced no clinical benefit in this trial, and further dose finding studies in early disease stages and for longer duration are warranted to examine GSK-3 inhibition in AD patients.