Journal ArticleDOI
Novel polyphosphazene/poly(lactide-co-glycolide) blends: miscibility and degradation studies
Sobrasua M. Ibim,Archel M. A. Ambrosio,Michael S. Kwon,Saadiq F. El-Amin,Harry R. Allcock,Cato T. Laurencin +5 more
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TLDR
Findings suggest that these novel biodegradable PLAGA/PPHOS blends may be useful for biomedical purposes.About:
This article is published in Biomaterials.The article was published on 1997-12-01. It has received 88 citations till now. The article focuses on the topics: Differential scanning calorimetry & Miscibility.read more
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Bone Tissue Engineering: Recent Advances and Challenges
TL;DR: The fundamentals of bone tissue engineering are discussed, highlighting the current state of this field, and the recent advances of biomaterial and cell-based research, as well as approaches used to enhance bone regeneration.
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Biomedical Applications of Biodegradable Polymers
TL;DR: This review summarizes the most recent advances in the field over the past 4 years, specifically highlighting new and interesting discoveries in tissue engineering and drug delivery applications.
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Bone Tissue Engineering: State of the Art and Future Trends
TL;DR: The present review pretends to give an exhaustive overview on all components needed for making bone tissue engineering a successful therapy, going from materials to scaffolds and from cells to tissue engineering strategies that will lead to "engineered" bone.
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Polymeric Materials for Bone and Cartilage Repair
TL;DR: Current strategies in scaffold-guided tissue engineering approach, involving the most employed biodegradable polymers, either of natural or synthetic origin, will be reported underlying the role played by both material structure–property relationship and scaffold architecture.
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Formulation aspects of biodegradable polymeric microspheres for antigen delivery.
TL;DR: This review provides an applicable summary of different formulation routes for the purpose of producing safe, qualified and efficacious products of microencapsulated peptide and protein antigens.
References
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Aliphatic Polyesters II. The Degradation of Poly(DL-lactide), Poly(e-caprolactone), and Their Copolymers in Vivo
TL;DR: The mechanisms of biodegradation of poly (DL-lactide), poly (epsilon-caprolactone), and copolymers of epsilon-caproate sequences with DL-dilactide, delta-valerolactone, and DL-epsil on-decalactone in rabbit were shown to be qualitatively similar.
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Biodegradable Bone Repair Materials: Synthetic Polymers and Ceramics,
TL;DR: This review is limited to those materials that have been shown to be tissue-tolerant and biodegradable, and to include certain synthetic polymers and ceramics.
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Foreign-body reactions to fracture fixation implants of biodegradable synthetic polymers
TL;DR: Biodegradable rods of polyglycolide or lactide- glycolide copolymer were used in the internal fixation of a variety of fractures and osteotomies in 516 patients, producing a fluctuant swelling at the implantation site after an average of 12 weeks.
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A new absorbable suture
E. J. Frazza,E. E. Schmitt +1 more
TL;DR: Braided sutures prepared from polyglycolic acid exhibit high strength, excellent handling properties, minimal tissue reactivity, and a similar but more reproducible absorption rate than catgut.
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Osteolytic changes accompanying degradation of absorbable fracture fixation implants.
TL;DR: In patients with a foreign-body reaction the osteolytic foci tended to occur in the deepest parts of the implant channels, however, after one year the normal structure of the bone was restored.