Orienting and Reorienting: The Locus Coeruleus Mediates Cognition through Arousal
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TLDR
Noradrenaline, released in forebrain structures, will facilitate sensory processing, enhance cognitive flexibility and executive function in the frontal cortex, and promote offline memory consolidation in limbic structures.About:
This article is published in Neuron.The article was published on 2012-10-04 and is currently open access. It has received 735 citations till now. The article focuses on the topics: Arousal & Locus coeruleus.read more
Citations
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Inhibition and impulsivity: Behavioral and neural basis of response control
Andrea Bari,Trevor W. Robbins +1 more
TL;DR: This review will review the current models of behavioral inhibition along with their expression via underlying brain regions, including those involved in the activation of the brain's emergency 'brake' operation, those engaged in more controlled and sustained inhibitory processes and other ancillary executive functions.
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An opportunity cost model of subjective effort and task performance.
TL;DR: It is argued that the phenomenology of effort can be understood as the felt output of these cost/benefit computations of the costs and benefits associated with task performance and motivates reduced deployment of these computational mechanisms in the service of the present task.
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Relationships between Pupil Diameter and Neuronal Activity in the Locus Coeruleus, Colliculi, and Cingulate Cortex.
TL;DR: It is shown that LC activation reliably anticipates changes in pupil diameter that either fluctuate naturally or are driven by external events during near fixation, as in many psychophysical tasks.
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Selective neuronal vulnerability in Parkinson disease.
TL;DR: The evidence for and against the spreading LP model are discussed, as well as evidence that cell-autonomous factors govern both α-syn pathology and neuronal death.
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Dynamic adaptation of large-scale brain networks in response to acute stressors
Erno J. Hermans,Marloes J. A. G. Henckens,Marloes J. A. G. Henckens,Marian Joëls,Guillén Fernández +4 more
TL;DR: It is argued that exposure to acute stress prompts a reallocation of resources to a salience network, promoting fear and vigilance, at the cost of an executive control network after stress subsides, which normalizes emotional reactivity and enhances higher-order cognitive processes important for long-term survival.
References
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TL;DR: Evidence for partially segregated networks of brain areas that carry out different attentional functions is reviewed, finding that one system is involved in preparing and applying goal-directed selection for stimuli and responses, and the other is specialized for the detection of behaviourally relevant stimuli.
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Evidence for the existence of monoamine-containing neurons in the central nervous system. i. demonstration of monoamines in the cell bodies of brain stem neurons.
Dahlstroem A,Fuxe K +1 more
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Brain stem reticular formation and activation of the EEG
G. Moruzzi,Horace W. Magoun +1 more
TL;DR: In this paper, it was shown that reticular activation is associated with the activation of the reticular formation of the brain stem, and that reticulus activation can be induced by low frequency stimulation of the diffuse thalamic projection system, rather than intra-cortical spread following the arrival of afferent impulses at the sensory receiving areas of the cortex.
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An Integrative Theory of Locus Coeruleus-Norepinephrine Function: Adaptive Gain and Optimal Performance.
TL;DR: In this article, the locus coeruleus-norepinephrine (LC-NE) system plays a more complex and specific role in the control of behavior than investigators previously thought.
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The Reorienting System of the Human Brain: From Environment to Theory of Mind
TL;DR: While originally conceptualized as a system for redirecting attention from one object to another, recent evidence suggests a more general role in switching between networks, which may explain recent evidence of its involvement in functions such as social cognition.