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Palladium-catalyzed cross-coupling reactions of organoboron compounds

Norio Miyaura, +1 more
- 01 Nov 1995 - 
- Vol. 95, Iss: 7, pp 2457-2483
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TLDR
In this paper, a cross-coupling reaction is proposed for coupling 1 -Alkenylboron Derivatives: Synthesis of Conjugated Dienes 6.
Abstract
B. Other Catalyti; Process by Transition-Metal Complexes IV. Cross-Coupling Reaction A. Coupling of 1 -Alkenylboron Derivatives: Synthesis of Conjugated Dienes 6. Coupling of Arylboron Derivatives: Synthesis of Biaryls C. Coupling of Alkylboron Derivatives D. Coupling with Triflates E. Synthesis of Vinylic Sulfides F. Coupling with lodoalkanes: Alkyl-Alkyl CouDlino G. Coupling with Other Organic Halides and Boron Reagents V. Head-to-Tail Coupling VI. Carbonylative Coupling VII. Alkoxycarbonylation and Dimerization VIII. Conclusion 2457 2458 2458

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Novel potent ligands for the central nicotinic acetylcholine receptor: synthesis, receptor binding, and 3D-QSAR analysis.

TL;DR: This work describes the synthesis of six novel series of potent ligands with nanomolar affinity for the alpha4beta2 nAChR subtype using the GRID/GOLPE methodology, and reveals that the steric interactions between the target and the compounds are of major importance for the affinity.
Journal ArticleDOI

Pd-PVP colloid as catalyst for Heck and carbonylation reactions: TEM and XPS studies

TL;DR: In this article, a Pd-PVP colloid with a diameter of 19.8 nm was found in [Bu4N]Br medium catalyzes for the coupling of bromobenzene with butyl acrylate and methoxycarbonylation of iodobenzenes reactions.
Patent

Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors

TL;DR: In this article, the authors presented hetero-aryl substituted pyrrolo[2,3-b]pyridines and heteroaryl substituted polypyrrole[2.3]-pyrimidines that modulate the activity of Janus kinases and are useful in the treatment of diseases related to activity of JKs.
Journal ArticleDOI

Simple, efficient, and modular syntheses of polyene natural products via iterative cross-coupling.

TL;DR: The discovery of air-stable and highly versatile B-protected haloalkenylboronic acid building blocks for iterative cross-coupling enable the total synthesis of polyene natural products with extraordinary levels of simplicity, efficiency, and modularity.
References
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Journal ArticleDOI

Comprehensive Organometallic Chemistry

Dietmar Seyferth
- 01 Jul 1984 - 
BookDOI

The chemistry of organic silicon compounds

TL;DR: A.R.Bassindale and P.G.Taylor as mentioned in this paper discussed the photochemistry of organosilicon compounds, A.R., B.B.Birkofer and O.Ojima.
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