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Performance standards for antimicrobial susceptibility testing, ninth informational supplement

P Wayne
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The article was published on 2008-01-01 and is currently open access. It has received 1541 citations till now.

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Updated Functional Classification of β-Lactamases

Karen Bush, +1 more
- 01 Mar 2010 - 
TL;DR: The functional classification scheme updated herein is based on the 1995 proposal and includes group 1 (class C) cephalosporinases; group 2 (classes A and D) broad-spectrum, inhibitor-resistant, and extended-spectrums β-lactamases and serine carbapenemases; and group 3 metallo-β-lacticamases.
Journal ArticleDOI

Outcomes of carbapenem-resistant Klebsiella pneumoniae infection and the impact of antimicrobial and adjunctive therapies.

Gopi Patel, +3 more
- 30 Oct 2008 - 
TL;DR: The mortality rate associated with carbapenem-resistant K. pneumoniae infection and the limited antimicrobial options for treatment of carbapnem- resistant K.neume infection highlight the need for improved detection and development of novel agents with reliable clinical efficacy against this type of infection.
Journal ArticleDOI

Prevalence in the United States of aac(6′)-Ib-cr Encoding a Ciprofloxacin-Modifying Enzyme

Chi Hye Park, +4 more
- 01 Nov 2006 - 
TL;DR: Aac(6′)-Ib-cr was geographically widespread, stable over time, most common in Escherichia coli, equally prevalent in ciprofloxacin-susceptible and -resistant strains, and not associated with qnr genes.
Journal ArticleDOI

Colistin Resistance in Acinetobacter baumannii Is Mediated by Complete Loss of Lipopolysaccharide Production

Jennifer H. Moffatt, +16 more
- 01 Dec 2010 - 
TL;DR: It is shown that A. baumannii can rapidly develop resistance to polymyxin antibiotics by complete loss of the initial binding target, the lipid A component of lipopolysaccharide (LPS), which has long been considered to be essential for the viability of Gram-negative bacteria.
Journal ArticleDOI

Is Neisseria gonorrhoeae Initiating a Future Era of Untreatable Gonorrhea?: Detailed Characterization of the First Strain with High-Level Resistance to Ceftriaxone

Makoto Ohnishi, +8 more
- 01 Jul 2011 - 
TL;DR: A detailed characterization of the first Neisseria gonorrhoeae strain, H041, was performed to confirm the finding, examine its antimicrobial resistance (AMR), and elucidate the resistance mechanisms.