Journal ArticleDOI
Poly (glutamic acid)--an emerging biopolymer of commercial interest.
Ishwar B. Bajaj,Rekha S. Singhal +1 more
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In this paper, the authors provide updated information on fermentative production of poly (γ-glutamic acid) by various bacterial strains and effect of fermentation conditions and media component on production of PGA in submerged as well as solid state fermentation.About:
This article is published in Bioresource Technology.The article was published on 2011-05-01. It has received 308 citations till now.read more
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Fabrication of Poly(γ-glutamic acid)-coated Fe3O4 Magnetic Nanoparticles and Their Application in Heavy Metal Removal
TL;DR: In this paper, poly(γ-glutamic acid)-coated Fe3O4 magnetic nanoparticles (γ-PGA/Fe 3O4 MNPs) were successfully fabricated using the co-precipitation method.
Journal ArticleDOI
pH-responsive physically and chemically cross-linked glutamic-acid-based hydrogels and nanogels
Luana Becker Peres,Luana Becker Peres,Raul Silva dos Anjos,Laura C. Tappertzhofen,Paulo Emilio Feuser,Pedro Henrique Hermes de Araújo,Katharina Landfester,Claudia Sayer,Rafael Muñoz-Espí,Rafael Muñoz-Espí +9 more
TL;DR: In this article, the synthesis of a glutamic-acid-based hydrogel by solution and inverse mini-emulsion polymerization is presented, and the results show that l -glutamic acid-based nanogels may have great potential in hydrophilic drug nanocarriers.
Journal ArticleDOI
Synthesis and characterization of an injectable ε-polylysine/carboxymethyl chitosan hydrogel used in medical application
Wang Yucan,Cao Hui,Wang Xinying +2 more
TL;DR: An injectable self-degrading hydrogel capable of rapid gelation, low toxicity and low irritation was prepared and has good application prospects in punctum embolization and medical hemostatic dressings.
Journal ArticleDOI
Effects of poly-γ-glutamic acid (γ-PGA) on plant growth and its distribution in a controlled plant-soil system
TL;DR: Improved plant nutrient uptake capacity and soil nutrient availability by γ-PGA may partly explain the promotional effect of γ -PGA, however, the underlying reason may be closely related to L-Glu.
Journal ArticleDOI
Calcium-mineralized polypeptide nanoparticle for intracellular drug delivery in osteosarcoma chemotherapy.
TL;DR: Given the superior properties of Ca-mineralized polypeptide nanoparticle for intracellular drug delivery, the smart drug delivery system showed strong competitiveness in clinical chemotherapy of cancers.
References
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Journal ArticleDOI
The production of poly-(γ-glutamic acid) from microorganisms and its various applications
Ing-Lung Shih,Yi-Tsong Van +1 more
TL;DR: In this article, the chemistry and biosynthesis of poly-(gamma-glutamic acid) (Gamma-PGA) produced by various strains of Bacillus are discussed.
Journal Article
Complete Regression of Well-established Tumors Using a Novel Water-soluble Poly(l-Glutamic Acid)-Paclitaxel Conjugate
Chun Li,Dong Fang Yu,Robert A. Newman,Fernando Cabral,L. Clifton Stephens,Nancy Hunter,Luka Milas,Sidney Wallace +7 more
TL;DR: Data suggest that in addition to its role as a carrier for selective delivery of paclitaxel to the tumor, PG-TXL exerts distinct pharmacological actions of its own that may contribute to its remarkable antitumor efficacy.
Journal ArticleDOI
Poly-gamma-glutamate in bacteria
Thomas Candela,Agnès Fouet +1 more
TL;DR: The anchoring of PGA to the bacterial surface is important for virulence and all cap genes are therefore potential targets for inhibitors specifically blocking PGA synthesis or anchorage.
Journal ArticleDOI
Production of a biopolymer flocculant from Bacillus licheniformis and its flocculation properties.
TL;DR: The comparison of the flocculating activity between the present biopolymers and a commercial lower molecular weight product showed that the biopolymer of the present study had much higher activity.
Journal ArticleDOI
Preparation of γ-PGA/chitosan composite tissue engineering matrices
TL;DR: In this article, gamma-poly(glutamic acid) (gamma-PGA), a hydrophilic and biodegradable polymer, was chosen to modify chitosan matrices to produce a gamma-PGAs/chitosans composite biomaterial.
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The production of poly-(γ-glutamic acid) from microorganisms and its various applications
Ing-Lung Shih,Yi-Tsong Van +1 more