Journal ArticleDOI
Potential hazards of bisphenol A exposure to semen quality and sperm DNA integrity among infertile men.
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TLDR
Total BPA levels were negatively associated with semen quality and antioxidant levels, and positively correlated with DNA damage, especially with multiple semen profile defects, alongside seminal-plasma lipid peroxidation.About:
This article is published in Reproductive Toxicology.The article was published on 2018-08-10. It has received 37 citations till now. The article focuses on the topics: Semen quality & Male infertility.read more
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Journal ArticleDOI
Endocrine-disrupting chemicals: implications for human health
TL;DR: Greater evidence has accumulated than was previously identified for cognitive deficits and attention-deficit disorder in children following prenatal exposure to bisphenol A, organophosphate pesticides, and polybrominated flame retardants.
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Endocrine Disruptors in Water and Their Effects on the Reproductive System.
TL;DR: This review discusses the occurrence of EDCs in water such as disinfection byproducts, fluorinated compounds, bisphenol A, phthalates, pesticides, and estrogens, and it outlines their adverse reproductive effects in non-human animals and humans.
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Oxidative Stress and BPA Toxicity: An Antioxidant Approach for Male and Female Reproductive Dysfunction.
TL;DR: Five classes of antioxidants—vitamins and co-factors, natural products (herbals and phytochemicals), melatonin, selenium, and methyl donors (used alone or in combination)—that have been found useful to counteract BPA toxicity in male and female reproductive functions are focused on.
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Endocrine disrupting chemicals: Impacts on human fertility and fecundity during the peri-conception period.
TL;DR: In this paper, the authors identify and review strong peer-reviewed evidence regarding the effects of environmentally-relevant EDC concentrations on adult male and female fertility during the critical periconception period on reproductive hormone concentrations, gamete and embryo characteristics, as well as the time to pregnancy in the general population.
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Environmental contaminants and male infertility: Effects and mechanisms.
TL;DR: The escalating prevalence of male infertility and decreasing trend in sperm quality have been correlated with rapid industrialisation and the associated discharge of an excess of synthetic substances into the environment and the possible mechanisms of action are discussed.
References
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Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
TL;DR: Using this method, the liped peroxide level in the liver of rats suffering from carbon tetrachloride intoxication was investigated and was in good agreement with previously reported data obtained by measuring diene content.
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A simple technique for quantitation of low levels of DNA damage in individual cells
TL;DR: Human lymphocytes were exposed to X-irradiation or treated with H2O2 and the extent of DNA migration was measured using a single-cell microgel electrophoresis technique under alkaline conditions and this technique appears to be sensitive and useful for detecting damage and repair in single cells.
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Exposure of the U.S. population to bisphenol A and 4-tertiary-octylphenol: 2003-2004
TL;DR: Urine concentrations of total BPA differed by race/ethnicity, age, sex, and household income, and these first U.S. population representative concentration data for urinary BPA and tOP should help guide public health research priorities.
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Method for the measurement of antioxidant activity in human fluids
TL;DR: This method is easy, rapid, reliable, and practical for the routine measurement of total antioxidant activity in serum and other human body fluids and is comparable with the reference (Randox) method.