Journal ArticleDOI
Associations of bisphenol A and polychlorinated biphenyls with spermatogenesis and steroidogenesis in two biological fluids from men attending an infertility clinic
Jana Vitku,Jiri Heracek,Lucie Sosvorova,Richard Hampl,Tereza Chlupacova,Martin Hill,Vladimír Sobotka,Marie Bičíková,Luboslav Stárka +8 more
TLDR
The data indicate that BPA influences human gonadal and adrenal steroidogenesis at various steps, and may negatively contribute to the final state of sperm quality.About:
This article is published in Environment International.The article was published on 2016-04-01. It has received 112 citations till now. The article focuses on the topics: Testosterone & Endocrine disruptor.read more
Citations
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Journal ArticleDOI
Endocrine-disrupting chemicals: implications for human health
TL;DR: Greater evidence has accumulated than was previously identified for cognitive deficits and attention-deficit disorder in children following prenatal exposure to bisphenol A, organophosphate pesticides, and polybrominated flame retardants.
Journal ArticleDOI
Current Knowledge on Endocrine Disrupting Chemicals (EDCs) from Animal Biology to Humans, from Pregnancy to Adulthood: Highlights from a National Italian Meeting
Maria E. Street,Sabrina Angelini,Sergio Bernasconi,Ernesto Burgio,Alessandra Cassio,Cecilia Catellani,Francesca Cirillo,Annalisa Deodati,Enrica Fabbrizi,Vassilios Fanos,Giancarlo Gargano,Enzo Grossi,Lorenzo Iughetti,Pietro Lazzeroni,Alberto Mantovani,Lucia Migliore,Paola Palanza,Giancarlo Panzica,Anna Maria Papini,Stefano Parmigiani,Barbara Predieri,Chiara Sartori,Gabriele Tridenti,Sergio Amarri +23 more
TL;DR: This manuscript reviews the reports of a multidisciplinary national meeting on endocrine disrupting chemicals and suggests effects of EDCs on prenatal growth, thyroid function, glucose metabolism and obesity, puberty, fertility, and on carcinogenesis mainly through epigenetic mechanisms.
Journal ArticleDOI
Bisphenol A and its analogues: A comprehensive review to identify and prioritize effect biomarkers for human biomonitoring
Vicente Mustieles,Shereen Cynthia D'Cruz,Stephan Couderq,Andrea Rodríguez-Carrillo,Jean-Baptiste Fini,Tim Hofer,Inger-Lise Steffensen,Hubert Dirven,Robert Barouki,Nicolás Olea,Mariana F. Fernández,Arthur David +11 more
TL;DR: This work provides first an overview of all epigenetics, gene transcription, oxidative stress, reproductive, glucocorticoid and thyroid hormones, metabolic and allergy/immune biomarkers previously studied, and promising effect biomarkers related to altered neurodevelopmental and reproductive outcomes are prioritized, providing mechanistic insights based on in vitro, animal studies and AOP information.
Journal ArticleDOI
Urinary bisphenol A concentrations are associated with reproductive parameters in young men.
Evdochia Adoamnei,Jaime Mendiola,F. Vela-Soria,Mariana F. Fernández,Nicolás Olea,Niels Jørgensen,Shanna H. Swan,Alberto M. Torres-Cantero +7 more
TL;DR: The hypothesis that BPA exposure may be associated with a reduction in Leydig cell capacity (increased LH levels) and decreased sperm counts in young men is supported.
Journal ArticleDOI
Effects of bisphenol A on male and couple reproductive health: a review
TL;DR: Overall, the evidence supporting an association between BPA exposure and adverse male reproductive health outcomes in humans remains limited and inconclusive.
References
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Journal ArticleDOI
Endocrine-Disrupting Chemicals: An Endocrine Society Scientific Statement
Evanthia Diamanti-Kandarakis,Jean-Pierre Bourguignon,Linda C. Giudice,Russ Hauser,Gail S. Prins,Ana M. Soto,R. Thomas Zoeller,Andrea C. Gore +7 more
TL;DR: The evidence that endocrine disruptors have effects on male and female reproduction, breast development and cancer, prostate cancer, neuroendocrinology, thyroid, metabolism and obesity, and cardiovascular endocrinology is presented.
Journal ArticleDOI
A Critical Evaluation of Simple Methods for the Estimation of Free Testosterone in Serum
TL;DR: The FT value, obtained by calculation from T and SHBG as determined by immunoassay, appears to be a rapid, simple, and reliable index of bioavailable T, comparable to AFTC and suitable for clinical routine, except in pregnancy.
Journal ArticleDOI
Estimation of Average Concentration in the Presence of Nondetectable Values
TL;DR: In this article, the average concentration of a particular contaminant during some period of time, a certain proportion of the collected samples is often reported to be below the limit of detection.
Journal ArticleDOI
Chapel Hill bisphenol A expert panel consensus statement: integration of mechanisms, effects in animals and potential to impact human health at current levels of exposure.
Frederick S. vom Saal,Benson T. Akingbemi,Scott M. Belcher,Linda S. Birnbaum,D. Andrew Crain,Marcus Eriksen,Francesca Farabollini,Louis J. Guillette,Russ Hauser,Jerrold J. Heindel,Shuk-Mei Ho,Patricia A. Hunt,Taisen Iguchi,Susan Jobling,Jun Kanno,Ruth A. Keri,Karen E. Knudsen,Hans Laufer,Gerald A. LeBlanc,Michele Marcus,John A. McLachlan,John Peterson Myers,Angel Nadal,Retha R. Newbold,Nicolás Olea,Gail S. Prins,Catherine A. Richter,Beverly S. Rubin,Carlos Sonnenschein,Ana M. Soto,Chris E. Talsness,John G. Vandenbergh,Laura N. Vandenberg,Debby Walser-Kuntz,Cheryl S. Watson,Wade V. Welshons,Yelena B. Wetherill,R. Thomas Zoeller +37 more
TL;DR: This document is a summary statement of the outcome from he meeting: “Bisphenol A: An Examination of the Relevance of cological, In vitro and Laboratory Animal Studies for Assessng Risks to Human Health” sponsored by both the NIEHS and IDCR at NIH/DHHS.
Journal ArticleDOI
Inhibition of Testicular Steroidogenesis by the Xenoestrogen Bisphenol A Is Associated with Reduced Pituitary Luteinizing Hormone Secretion and Decreased Steroidogenic Enzyme Gene Expression in Rat Leydig Cells
TL;DR: Exposure of humans to bisphenol A (BPA), a monomer in polycarbonate plastics and a constituent of resins used in food packaging and dentistry, is significant and further studies are warranted to assess the effects of BPA on male fertility.