Prediction of Neurological Impairment in Cervical Spondylotic Myelopathy using a Combination of Diffusion MRI and Proton MR Spectroscopy
TLDR
A linear combination of DTI and MRS measurements within the cervical spinal cord may be useful for accurately predicting neurological deficits in patients with cervical spondylosis.Abstract:
Purpose
In the present study we investigated a combination of diffusion tensor imaging (DTI) and magnetic resonance spectroscopic (MRS) biomarkers in order to predict neurological impairment in patients with cervical spondylosis.read more
Citations
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Journal ArticleDOI
Future Directions and New Technologies for the Management of Degenerative Cervical Myelopathy
TL;DR: The diagnosis and treatment of degenerative cervical myelopathy (DCM) has been evolving over the past 5 decades as a result of collaborations between clinicians and scientists.
Journal ArticleDOI
The role of diffusion tensor imaging in the diagnosis, prognosis, and assessment of recovery and treatment of spinal cord injury: a systematic review
Orel A. Zaninovich,Mauricio J. Avila,Matthew D. Kay,Jennifer L. Becker,R. John Hurlbert,Nikolay L. Martirosyan +5 more
TL;DR: SDTI and its metrics have great potential to become a powerful clinical tool in SCI, however, the current limitations of DTI preclude its use beyond research and into clinical practice.
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Cervical Spondylotic Myelopathy: Natural Course and the Value of Diagnostic Techniques -WFNS Spine Committee Recommendations
Mehmet Zileli,Sachin A Borkar,Sumit Sinha,Rui Reinas,Óscar L. Alves,Se-Hoon Kim,Sumeet Pawar,Bala Murali,J.K.B.C. Parthiban +8 more
TL;DR: A systematic literature review was conducted to determine most up-to-date information on the natural outcome of cervical spondylotic myelopathy (CSM) and the most reliable diagnostic techniques and electrophysiological tests used in CSM patients.
Journal ArticleDOI
Diffusion Tensor Imaging of the Spinal Cord: Clinical Value, Investigational Applications, and Technical Limitations.
TL;DR: The clinical and investigational applications of spinal cord DTI, as well as the practical difficulties and limitations of DWI and DTI for the evaluation of the spinal cord are examined.
Journal ArticleDOI
Is cervical disc arthroplasty good for congenital cervical stenosis
Peng Yuan Chang,Hsuan Kan Chang,Jau Ching Wu,Wen Cheng Huang,Li Yu Fay,Tsung Hsi Tu,Ching Lan Wu,Henrich Cheng +7 more
TL;DR: In this article, the authors performed a retrospective review of patients who underwent 3-level anterior cervical discectomy and fusion (ACDF) and found that the hybrid-CDA strategy yielded similar clinical improvement to 3-Level ACDF in patients with myelopathy caused by CCS.
References
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Non-invasive mapping of connections between human thalamus and cortex using diffusion imaging
Timothy E.J. Behrens,Heidi Johansen-Berg,Mark W. Woolrich,Mark W. Woolrich,Stephen M. Smith,Claudia A. M. Wheeler-Kingshott,P A Boulby,Gareth J. Barker,E L Sillery,K Sheehan,Olga Ciccarelli,Alan J. Thompson,J. M. Brady,Paul M. Matthews +13 more
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Robust determination of the fibre orientation distribution in diffusion MRI: non-negativity constrained super-resolved spherical deconvolution.
TL;DR: The introduction of a constraint on such negative regions is proposed to improve the conditioning of the spherical deconvolution, and this approach is shown to provide FOD estimates that are robust to noise whilst preserving angular resolution.
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Optimal strategies for measuring diffusion in anisotropic systems by magnetic resonance imaging.
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N-Acetylaspartate in the CNS: From neurodiagnostics to neurobiology
John R. Moffett,Brian D. Ross,Peethambaran Arun,Chikkathur N. Madhavarao,Aryan M.A. Namboodiri +4 more
TL;DR: Evidence suggests that NAA is a direct precursor for the enzymatic synthesis of the neuron specific dipeptides N-acetylaspartylglutamate, the most concentrated neuropeptide in the human brain, and it is proposed that N AA may also be involved in brain nitrogen balance.
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Interobserver and Intraobserver Reliability of the Japanese Orthopaedic Association Scoring System for Evaluation of Cervical Compression Myelopathy
TL;DR: The inter- and intraobserver reliabilities of the revised scoring system for cervical myelopathy proposed by the Japanese Orthopedic Association were high, suggesting that this system is useful for assessment of cervicalMyelopathy in comparative studies of treatment.