Journal ArticleDOI
Preparation and characterization of novel antibacterial blended films based on modified carboxymethyl cellulose/phenolic compounds
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TLDR
In this paper, a cross-linked blend films based on the biocompatible modified carboxymethyl cellulose (m-CMC) with phenolic compounds (Ph) extracted from sesame seed meal were developed.Abstract:
The objective of this work is to re-use of agriculture waste via an environmentally friendly procedure to introduce multifunctional cellulose-based blend films using sesame seed meal extracted from agriculture wastes. The current strategy demonstrated the identification and evaluation of the bioactive compounds of sesame seed meal extracted from agricultural wastes via an ultrasonic procedure. Then, the sesame seed meal extract was loaded onto modified carboxymethyl cellulose within a matrix of a blend film. A cross-linked blend films based on the biocompatible modified carboxymethyl cellulose (m-CMC) with phenolic compounds (Ph) extracted from sesame seed meal were developed. The cross-linked m-CMC/Ph films were investigated by Fourier transform infrared spectroscopic analysis, while the surface morphology was investigated using scanning electron microscopy. Both mechanical and swelling properties were investigated. The m-CMC/Ph film exhibited excellent antioxidant performance as well as antibacterial activity against Staphylococcus aureus as Gram-positive pathogenic bacteria and Pseudomonas aeruginosa as Gram-negative pathogenic bacteria using colony-forming unit to provide further biocompatibility for prepared blend films. Additionally, molecular docking studies were carried out on effective films to evaluate their potential interaction against P. aeruginosa LolA (PDB: 2W7Q) and S. aureus metalloproteinase (PDB:1BQB) with a binding energy of − 3.7 kcal/mol and − 2.8 kcal/mol and short bond length of 2.076 A and 1.144 A, respectively. The computational calculations of the optimized monomer CMC and gallic acid were carried out to elucidate the HOMO–LUMO energy gap and interaction between them as well as the optimization of m-CMC/Ph to evaluate their interaction and film stability. As a result, the present study presents a novel simple approach to design smart biocompatible films for multifunctional healthcare and medical purposes using the biologically active extracts from sustainable plant wastes.read more
Citations
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Journal ArticleDOI
Nanocellulose aerogel for highly efficient adsorption of uranium (VI) from aqueous solution.
TL;DR: In this article, a cellulose nanofibers (CNFs) aerogel was prepared via simple covalent crosslinking and freeze-drying method, which showed high specific surface area and high metal-chelating capacity.
Journal ArticleDOI
Synthesis of cellulose based amino acid functionalized nano-biocomplex: Characterization, antifungal activity, molecular docking and hemocompatibility
TL;DR: DAC/Gly/Zn is a promising nano-biocomplex as antifungal agent and exhibited non-hemolytic effect on human RBCs at concentrations upto 2.5 mg/ml.
Journal ArticleDOI
Innovative synthesis of modified cellulose derivative as a uranium adsorbent from carbonate solutions of radioactive deposits
TL;DR: In this article, a new eco-friendly adsorbent for the recovery of uranium from the Egyptian radioactive deposits was presented, where cellulose/p-toluidine was prepared as a potential sorbent for uranium (VI) in highly alkaline solutions, from a condensation reaction of toluene with dialdehyde cellulose which resulting from periodate selective oxidative of cellulose.
Journal ArticleDOI
Synthesis of novel β-lactams: Antioxidant activity, acetylcholinesterase inhibition and computational studies
TL;DR: In this paper, a convenient synthesis of β-lactam derivatives with interesting pharmacological activities was described, some of the synthesized compounds exhibited excellent antioxidant activity and showed acetylcholinesterase inhibition.
Journal ArticleDOI
Development of 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methyl-morpholinium chloride cross-linked carboxymethyl cellulose films.
Valentina Beghetto,Vanessa Gatto,Silvia Conca,Noemi Bardella,Chiara Buranello,Giulia Gasparetto,Roberto Sole +6 more
TL;DR: Data reported show that DMTMM can efficiently cross-link CMC to produce films for food packaging with best compromise between high water resistance, vapour permeability and mechanical properties.
References
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Antibacterial Properties of Polyphenols: Characterization and QSAR (Quantitative Structure-Activity Relationship) Models.
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Antimicrobial activity of phenolic compounds identified in wild mushrooms, SAR analysis and docking studies
Maria José Alves,Maria José Alves,Isabel C.F.R. Ferreira,Hugo J.C. Froufe,Rui M.V. Abreu,Anabela Martins,Manuela Pintado +6 more
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Journal ArticleDOI
Antimicrobial activity of some natural dyes
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Journal ArticleDOI
Preparation and properties of dialdehyde carboxymethyl cellulose crosslinked gelatin edible films
TL;DR: In this article, the mechanical properties, thermal stability, light barrier properties, swelling behavior as well as water vapor permeability of gelatin-carboxymethyl cellulose (DCMC) films are investigated.
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