Journal ArticleDOI
Preparation and characterization of thermosensitive pluronic F127-b-poly(ɛ-caprolactone) mixed micelles
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TLDR
Both pure and mixed micelles of F127-CL with CL length of 200 show thermo-responsivities from 25 to 45°C, while form larger aggregations at high temperature, and the hemolysis and coagulation assays showed that the micells possess good blood compatibility.About:
This article is published in Colloids and Surfaces B: Biointerfaces.The article was published on 2011-08-01. It has received 74 citations till now. The article focuses on the topics: Micelle & Drug carrier.read more
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Curcumin loaded mixed micelles composed of Pluronic P123 and F68: preparation, optimization and in vitro characterization.
Liyan Zhao,Jianchao Du,Yuwei Duan,Ya’ni Zang,Huaisong Zhang,Chunfen Yang,Fengliang Cao,Guangxi Zhai +7 more
TL;DR: It could be concluded from the results that P123/F68 mixed micelles might serve as a potential nanocarrier to improve the solubility and biological activity of Cur.
Journal ArticleDOI
Enhanced oral bioavailability and anticancer activity of novel curcumin loaded mixed micelles in human lung cancer cells.
TL;DR: The present work proposes the formulation of mixed micelles of PF127 and GL44 which can act as promising carrier systems for hydrophobic drugs such as curcumin with significant improvement in their oral bioavailability.
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Self-assembled micelles of novel amphiphilic copolymer cholesterol-coupled F68 containing cabazitaxel as a drug delivery system
Yanzhi Song,Qingjing Tian,Zhenjun Huang,Fan Di,Zhennan She,Xinrong Liu,Cheng Xiaobo,Bin Yu,Yihui Deng +8 more
TL;DR: The F68-CHMC copolymer may be a potential nanocarrier to improve the solubility and biological activity of cabazitaxel and other hydrophobic drugs.
Journal ArticleDOI
Superparamagnetic iron oxide nanoparticles dispersed in Pluronic F127 hydrogel: potential uses in topical applications
L. C. Gonçalves,Amedea B. Seabra,Amedea B. Seabra,Milena T. Pelegrino,Milena T. Pelegrino,Daniele Ribeiro de Araujo,Juliana S. Bernardes,Paula S. Haddad +7 more
TL;DR: In this article, the synthesis and characterization of nitric oxide (NO)-releasing superparamagnetic iron oxide nanoparticles (Fe3O4 NPs), and their incorporation in Pluronic F127 hydrogel with great potential for topical applications are discussed.
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Surfactant-modified chemically reduced graphene oxide for electrochemical supercapacitors
TL;DR: In this paper, an easy method to synthesize surfactant-modified graphene for a supercapacitor is demonstrated through the intercalation of graphene oxide (GO) with a triblock copolymer Pluronic F127 (F127).
References
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Drug Delivery Systems: Entering the Mainstream
TL;DR: There is considerable interest in exploiting the advantages of DDS for in vivo delivery of new drugs derived from proteomics or genomics research and for their use in ligand-targeted therapeutics.
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Impact of Nanotechnology on Drug Delivery
TL;DR: This work focuses on the application of nanotechnology to drug delivery and highlights several areas of opportunity where current and emerging nanotechnologies could enable entirely novel classes of therapeutics.
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Poly(ethylene oxide)-poly(propylene oxide )-poly (ethylene oxide) block copolymer surfactants in aqueous solutions and at interfaces: thermodynamics, structure, dynamics, and modeling
TL;DR: In this article, the association properties of poly(ethylene oxide)-block-poly(propyleneoxide)-blockpoly(methylene oxide) (PEO) copolymers in aqueous solutions, and the adsorption at interfaces are reviewed.
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Block copolymer micelles as vehicles for drug delivery
TL;DR: In this article, the authors focused on the promising features of block copolymer micelles as drug vehicles mimicking the natural carrier-systems with supramolecular structures (i.e. viruses and lipoproteins).
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Thermoreversible Gelation of PEG−PLGA−PEG Triblock Copolymer Aqueous Solutions
TL;DR: Aqueous solutions of new biodegradable triblock copolymers, poly(ethylene glycol-b-(dl-lactic acid-co-glycolic acid)-b-ethylenes glycol) (PEG−PLGA−PEG), have shown to have sol-to-gel (lower transiti...