Prognostic value of neurohumoral activation in patients with an acute myocardial infarction : effect of captopril
Jean L. Rouleau,Milton Packer,Lemuel A. Moyé,Jacques de Champlain,Daniel G. Bichet,Marc Klein,Jacques R. Rouleau,Bruce Sussex,J. Malcolm O. Arnold,Francois Sestier,John O. Parker,Patricia McEwan,Victoria Bernstein,T. Edward Cuddy,Gervasio A. Lamas,Stephen S. Gottlieb,John McCans,Claude Nadeau,François Delage,Chuan Chuan C Wun,Marc A. Pfeffer +20 more
TLDR
Only plasma renin activity and aldosterone, atrial natriuretic peptide and arginine vasopressin were independent predictors of the combined end points of cardiovascular mortality, development of severe heart failure or recurrent myocardial infarction.About:
This article is published in Journal of the American College of Cardiology.The article was published on 1994-09-01 and is currently open access. It has received 285 citations till now. The article focuses on the topics: Captopril & Plasma renin activity.read more
Citations
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Attenuation of Compensation of Endogenous Cardiac Natriuretic Peptide System in Chronic Heart Failure Prognostic Role of Plasma Brain Natriuretic Peptide Concentration in Patients With Chronic Symptomatic Left Ventricular Dysfunction
Takayoshi Tsutamoto,Atsuyuki Wada,Keiko Maeda,Tomoko Hisanaga,Yukiharu Maeda,Daisuke Fukai,Masato Ohnishi,Yoshihisa Sugimoto,Masahiko Kinoshita +8 more
TL;DR: It is indicated that plasma BNP is more useful than ANP for assessing the mortality in patients with chronic CHF and that the plasma levels of BNP provide prognostic information independent of other variables previously associated with a poor prognosis.
Journal ArticleDOI
Plasma brain natriuretic peptide as a biochemical marker of high left ventricular end-diastolic pressure in patients with symptomatic left ventricular dysfunction☆☆☆★★★
TL;DR: Findings suggest that plasma BNP is superior to ANP as a predictor of high LVEDP in patients with symptomatic left ventricular dysfunction.
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Plasma Brain Natriuretic Peptide as an Indicator of Left Ventricular Systolic Function and Long-term Survival After Acute Myocardial Infarction Comparison With Plasma Atrial Natriuretic Peptide and N-Terminal Proatrial Natriuretic Peptide
Torbjørn Omland,A. Aakvaag,Vernon V. S. Bonarjee,Kenneth Caidahl,Rolv Terje Lie,Dennis W.T. Nilsen,Johan Sundsfjord,Kenneth Dickstein +7 more
TL;DR: Although plasma ANP appears to be a better predictor of left ventricular dysfunction, plasma BNP may have greater potential to complement standard prognostic indicators used in risk stratification after AMI because of its strong, independent association with long-term survival, enhanced in vitro stability, and simplicity of analysis.
Journal ArticleDOI
Plasma N-Terminal Pro–Brain Natriuretic Peptide and Adrenomedullin New Neurohormonal Predictors of Left Ventricular Function and Prognosis After Myocardial Infarction
A. M. Richards,M G Nicholls,Timothy G. Yandle,Chris Frampton,Eric A. Espiner,J. G. Turner,R C Buttimore,John G. Lainchbury,John Elliott,Hamid Ikram,Ian Crozier,David Smyth +11 more
TL;DR: Plasma N-BNP measured 2 to 4 days after myocardial infarction independently predicted left ventricular function and 2-year survival and Stratification of patients into low- and high-risk groups can be facilitated by plasma natriuretic peptide or BNP measurements, and one of these could reasonably be included in the routine clinical workup of patients after my cardiac infarctions.
Journal ArticleDOI
Plasma Norepinephrine Predicts Survival and Incident Cardiovascular Events in Patients With End-Stage Renal Disease
Carmine Zoccali,Francesca Mallamaci,Saverio Parlongo,Sebastiano Cutrupi,Francesco A. Benedetto,Giovanni Tripepi,Graziella Bonanno,Francesco Rapisarda,Pasquale Fatuzzo,Giuseppe Seminara,Alessandro Cataliotti,Benedetta Stancanelli,Lorenzo Malatino +12 more
TL;DR: Sympathetic nerve overactivity is associated with mortality and cardiovascular outcomes in ESRD and controlled trials with antiadrenergic drugs are needed to determine whether interference with the sympathetic system could reduce the high cardiovascular morbidity and mortality in dialysis patients.
References
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Journal ArticleDOI
Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. results of the survival and ventricular enlargement trial
Marc A. Pfeffer,Eugene Braunwald,Lemuel A. Moyé,Lofty L. Basta,Edward J. Brown,Thomas E. Cuddy,Barry R. Davis,Edward M. Geltman,Steven Goldman,Greg C. Flaker,Marc Klein,Gervasio A. Lamas,Milton Packer,Jacques R. Rouleau,Jean L. Rouleau,John D. Rutherford,John H. Wertheimer,C. Morton Hawkins +17 more
TL;DR: In patients with asymptomatic left ventricular dysfunction after myocardial infarction, long-term administration of captopril was associated with an improvement in survival and reduced morbidity and mortality due to major cardiovascular events.
Journal ArticleDOI
Beta blockade during and after myocardial infarction: an overview of the randomized trials
TL;DR: The aim has been not only to review the 65-odd randomized beta blocker trials but also to demonstrate that when many randomized trials have all applied one general approach to treatment, it is often not appropriate to base inference on individual trial results.
Journal ArticleDOI
Plasma Norepinephrine as a Guide to Prognosis in Patients with Chronic Congestive Heart Failure
Jay N. Cohn,T. B. Levine,Maria Teresa Olivari,Garberg,Lura D,Gary S. Francis,Ada B. Simon,Tom S. Rector +7 more
TL;DR: Measurements of Hemodynamics, plasma norepinephrine, and plasma renin activity in patients with moderate to severe congestive heart failure suggest that a single resting venous blood sample showing the plasma norenphrine concentration provides a better guide to prognosis than other commonly measured indexes of cardiac performance.
Journal ArticleDOI
Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction.
François Cambien,Odette Poirier,Laure Lecerf,Alun Evans,Jean-Pierre Cambou,Dominique Arveiler,Gérald Luc,Jean-Marie Bard,L Bara,Sylvain Ricard +9 more
TL;DR: It is reported that the DD genotype, which is associated with higher levels of circulating ACE than the ID and II genotypes, is significantly more frequent in patients with myocardial infarction than in controls, especially among subjects with low body-mass index and low plasma levels of ApoB.
Journal ArticleDOI
Comparison of neuroendocrine activation in patients with left ventricular dysfunction with and without congestive heart failure. A substudy of the Studies of Left Ventricular Dysfunction (SOLVD).
Gary S. Francis,Claude R. Benedict,David E. Johnstone,Philip C. Kirlin,John Nicklas,Chang Seng Liang,Spencer H. Kubo,Elizabeth Rudin-Toretsky,Salim Yusuf +8 more
TL;DR: It is concluded that neuroendocrine activation occurs in patients with left ventricular dysfunction and no heart failure, and is further increased as overt heart failure ensues and diuretics are added to therapy.