Journal ArticleDOI
Quality of life assessment in clinical trials: methodologic issues.
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TLDR
This article reviews a number of the central methodologic issues surrounding the development or selection of quality of life measures appropriate for use in clinical trials and focuses on research design and implementation issues in clinical trial-based quality oflife studies.About:
This article is published in Controlled Clinical Trials.The article was published on 1989-12-01. It has received 157 citations till now. The article focuses on the topics: Quality of life & Research design.read more
Citations
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Evaluating patient-based outcome measures for use in clinical trials.
TL;DR: This research highlights the need to understand more fully the rationale behind the continued use of these devices, as well as the barriers to their adoption.
Journal ArticleDOI
Assessing the quality of randomized controlled trials: An annotated bibliography of scales and checklists
TL;DR: An annotated bibliography of scales and checklists developed to assess quality is presented, giving readers a quantitative index of the likelihood that the reported methodology and results are free of bias.
Journal ArticleDOI
The role of health care providers and significant others in evaluating the quality of life of patients with chronic disease: A review
TL;DR: There is need for more methodologically sound studies that incorporate head-to-head comparisons of health care providers and significant others as proxy raters and employ well-validated quality-of-life measures and employ a longitudinal design in order to examine the effect of changes in patients' health status over time on the ability of proxies to provide valid quality- of-life assessments.
Journal ArticleDOI
Quality of Life in Individuals With Anxiety Disorders
TL;DR: It is expected that a more thorough understanding of the impact on quality of life will lead to increased public awareness of anxiety disorders as serious mental disorders worthy of further investment in research, prevention, and treatment.
Journal ArticleDOI
Quality of life measures in health care. I: Applications and issues in assessment.
Ray Fitzpatrick,Astrid E. Fletcher,Sheila M. Gore,David R. Jones,David Spiegelhalter,David Cox +5 more
TL;DR: The instruments available and their application in screening programmes, audit, health care research, and clinical trials are reviewed; using the appropriate instrument is essential if outcome measures are to be valid and clinically meaningful.
References
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Journal ArticleDOI
Convergent and discriminant validation by the multitrait-multimethod matrix.
TL;DR: This transmutability of the validation matrix argues for the comparisons within the heteromethod block as the most generally relevant validation data, and illustrates the potential interchangeability of trait and method components.
Journal ArticleDOI
The Sickness Impact Profile: development and final revision of a health status measure.
TL;DR: In this article, the authors developed the Sickness Impact Profile (SIP), a behaviorally based measure of health status, and evaluated its reliability and validity using multitrait-multimethod technique.
Journal ArticleDOI
Measuring the quality of life of cancer patients: a concise QL-index for use by physicians.
Walter O. Spitzer,Walter O. Spitzer,Annette J. Dobson,Annette J. Dobson,Jane Hall,Jane Hall,Esther Chesterman,Esther Chesterman,John Levi,John Levi,Richard Shepherd,Richard Shepherd,Renaldo N. Battista,Renaldo N. Battista,Barry R. Catchlove,Barry R. Catchlove +15 more
TL;DR: The aim has been to provide a new measure that can help physicians assess the relative benefits and risks of various treatments for serious illness and of supportive programs such as palliative care or hospice service.
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