Journal ArticleDOI
Racemic and enantiopure 4-(piperidine-2′-yl)-pyridazines: novel synthesis of anabasine-analogues with potential nicotinic acetylcholine receptor agonist activity—a new approach via Diels–Alder reaction with inverse electron demand
TLDR
In this article, a multistep synthesis of anabasine analogues bearing a bioisosteric pyridazine moiety instead of a pyridine nucleus in 2-position of the piperidine ring of the alkaloid is described.About:
This article is published in Tetrahedron.The article was published on 2002-02-11. It has received 34 citations till now. The article focuses on the topics: Enantiopure drug & Anabasine.read more
Citations
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Journal ArticleDOI
Arylglyoxals in synthesis of heterocyclic compounds.
Journal ArticleDOI
Recent advances and applications in 1,2,4,5-tetrazine chemistry
TL;DR: A review of the chemistry of 1,2,4,5-tetrazine and its derivatives in the last 10 years for the period 1996-2006 can be found in this paper.
Book ChapterDOI
Pyrimidines and their Benzo Derivatives
TL;DR: The chemistry of pyrimidines and their benzo derivatives, including quinazolines, perimidines, and benzo[gh]perimidine is reviewed in this article, with particular attention paid to work published between 1996 and 2007.
Journal ArticleDOI
Synthesis of Phenanthro[9,10‐b]indolizidin‐9‐ones, Phenanthro[9,10‐b]quinolizidin‐9‐one, and Related Benzolactams by Pd(OAc)2‐Catalyzed Direct Aromatic Carbonylation
TL;DR: Phenanthro[9,10-b]indolizidin-9-ones, phenanthro [9, 10b]quinolizidine-1-one, and related benzolactams were synthesized by benzoline ring formation using Pd(OAc)2-catalyzed direct aromatic carbonylation as mentioned in this paper.
Journal ArticleDOI
The azaphilic addition of organometallic reagents on tetrazines: scope and limitations
TL;DR: In this paper, a series of tetrazines were reacted with organometallic reagents and the results showed that reduction of the tetrazine or simple complex formation was the predominant transformation and usually high selectivity was observed.
References
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Book
Comprehensive Heterocyclic Chemistry II
TL;DR: In this article, the CHEC III is organized in 15 volumes and closely follows the organization used in the previous edition: Volumes 1 and 2: Cover respectively three and four-membered heterocycles, together with all fused systems containing a three- or four-measured heterocyclic ring.
Journal ArticleDOI
Oxidation of long-chain and related alcohols to carbonyls by dimethyl sulfoxide "activated" by oxalyl chloride
Book
Hetero Diels-Alder methodology in organic synthesis
Dale L. Boger,Steven M. Weinreb +1 more
TL;DR: In this article, N-Sulfinyl Compounds and Sulfur Diimides are classified into three classes: Nitroso and Thionitroso Dienophiles.
Related Papers (5)
Synthesis of Highly Substituted Pyridazines through Alkynyl Boronic Ester Cycloaddition Reactions
Asymmetric Total Synthesis of ent-(−)-Roseophilin: Assignment of Absolute Configuration
Dale L. Boger,Jiyong Hong +1 more
Synthesis of aromatic 1,2-diazines by inverse electron demand Diels-Alder reaction of polymer-supported 1,2,4,5-tetrazines
James S. Panek,Bin Zhu +1 more