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Journal ArticleDOI

Randomised trial of coronary intervention with antibody against platelet IIb/IIIa iritegrin for reduction of clinical restenosis: results at six months

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TLDR
The benefit of c 7E3 bolus/c7E3 infusion is extended from reducing abrupt closure and acute-phase adverse outcomes to a diminished need for subsequent coronary revascularisation procedures.
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This article is published in The Lancet.The article was published on 1994-04-09. It has received 840 citations till now. The article focuses on the topics: Bolus (medicine) & Placebo.

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Platelet glycoprotein IIb/IIIa receptor blockade and low-dose heparin during percutaneous coronary revascularization

TL;DR: Inhibition of the platelet glycoprotein IIb/IIIa receptor with abciximab, together with low-dose, weight-adjusted heparin, markedly reduces the risk of acute ischemic complications in patients undergoing percutaneous coronary revascularization, without increasing the riskof hemorrhage.
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The clinical implications of endothelial dysfunction.

TL;DR: This work suggests that studies of endothelial function could be used in the care of patients and as a surrogate marker for the evaluation of new therapeutic strategies, and a growing number of interventions known to reduce cardiovascular risk have been shown to improve endothelialfunction.
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Book ChapterDOI

Nonparametric Estimation from Incomplete Observations

TL;DR: In this article, the product-limit (PL) estimator was proposed to estimate the proportion of items in the population whose lifetimes would exceed t (in the absence of such losses), without making any assumption about the form of the function P(t).
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Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty.

TL;DR: Ischemic complications of coronary angioplasty and atherectomy were reduced with a monoclonal antibody directed against the platelet IIb/IIIa glycoprotein receptor, although the risk of bleeding was increased.
Journal ArticleDOI

Guidelines for percutaneous transluminal coronary angioplasty

TL;DR: The role of specific noninvasive and invasive procedures in the diagnosis and management of cardiovascular disease is defined and the contribution, uniqueness, sensitivity, specificity, indications, contraindications and cost-effectiveness of such specific procedures are addressed.
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