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Journal ArticleDOI

Reasons for worldwide decline in male fertility.

Uday Mann, +2 more
- 01 May 2020 - 
- Vol. 30, Iss: 3, pp 296-301
TLDR
There exist substantial data to suggest a decline in sperm counts over time, although causative factors have yet to be fully elucidated, potential causes include, increased rates of obesity, poor diet, and exposure to environmental toxins.
Abstract
Purpose of review To review the evidence regarding a decrease in worldwide sperm parameters and discuss potential causative factors. Recent findings The topic of worldwide decline in sperm parameters is contentious; however, recent high-quality studies have demonstrated that there is indeed a decline in sperm parameters. Several retrospective and basic science studies have shown possible links for this decline in sperm parameters such as obesity, diet, and environmental toxins. Summary There exist substantial data to suggest a decline in sperm counts over time. Although causative factors have yet to be fully elucidated, potential causes include, increased rates of obesity, poor diet, and exposure to environmental toxins. How this decline in sperm counts reflects fertility has yet to be determined. As such, further studies are necessary to evaluate whether this decline in sperm count correlates with decreased fecundity and how to identify and mitigate potential causative factors.

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Citations
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Perfluoroalkyl Chemicals and Male Reproductive Health: Do PFOA and PFOS Increase Risk for Male Infertility?

TL;DR: In this paper, the effects of poly-and perfluoroalkyl substances (PFAS) exposure on male reproductive health are discussed. And the mechanisms of action and possible toxic effects on the Leydig, Sertoli, and germ cells are discussed, and the sources of PFAS in drinking water are listed.
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Effects of a Lifestyle Change Intervention on Semen Quality in Healthy Young Men Living in Highly Polluted Areas in Italy: The FASt Randomized Controlled Trial.

TL;DR: In this article, the effect of a lifestyle intervention on semen quality of healthy young men living in highly polluted areas of Italy was evaluated using a randomized controlled trial, where the intervention group followed a 4-mo Mediterranean diet and moderate physical activity program, at which the participants showed an improvement of semen quality parameters.
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Effects of a Lifestyle Change Intervention on Semen Quality in Healthy Young Men Living in Highly Polluted Areas in Italy: The FASt Randomized Controlled Trial

TL;DR: In this article , a randomized controlled trial was conducted to evaluate the short-term effects of a diet and physical activity intervention on semen quality of healthy young men living in highly polluted areas of Italy.
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Impact of Heavy Metals on Human Male Fertility-An Overview.

TL;DR: In this article, the authors summarize the current knowledge on how heavy metals influence human male fertility and conclude that the development of adequate instruments for heavy metal assessment may play an important function in human male male fertility diagnosis and treatment.
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Semen quality as a potential susceptibility indicator to SARS-CoV-2 insults in polluted areas.

TL;DR: In this paper, a review article summarizes the relevant current observations emphasizing the weight that environmental pollution has on the sensitivity of a given population to several diseases and how semen quality, may be a potential indicator of sensitivity for virus insults in high polluted areas, and help to predict the risk for harmful effects of the SARS-CoV-2 epidemic.
References
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Journal ArticleDOI

Evidence for decreasing quality of semen during past 50 years.

TL;DR: There has been a genuine decline in semen quality over the past 50 years, and as male fertility is to some extent correlated with sperm count the results may reflect an overall reduction in male fertility.
Journal ArticleDOI

Global Disparities of Hypertension Prevalence and Control: A Systematic Analysis of Population-Based Studies From 90 Countries.

TL;DR: Global hypertension disparities are large and increasing and collaborative efforts are urgently needed to combat the emerging hypertension burden in low- and middle-income countries.
Journal ArticleDOI

Temporal trends in sperm count: a systematic review and meta-regression analysis.

TL;DR: This comprehensive meta-regression analysis reports a significant decline in sperm counts between 1973 and 2011, driven by a 50-60% decline among men unselected by fertility from North America, Europe, Australia and New Zealand.
Journal ArticleDOI

Surface nanogrooving of carbon microtubes.

TL;DR: The measurements showed that nanogrooving increases the surface area of carbon microtubes, as a result, die swelling of the extrudate is reduced and the mechanical strength of composite is reinforced due to stronger interactions between Nanogrooved carbon tubes and polymer matrix.
Trending Questions (2)
What are the causes of low sperm count?

The paper suggests that potential causes of low sperm count include increased rates of obesity, poor diet, and exposure to environmental toxins. However, further studies are needed to fully understand and mitigate these factors.

How do you deal with low sperm count?

As such, further studies are necessary to evaluate whether this decline in sperm count correlates with decreased fecundity and how to identify and mitigate potential causative factors.