Journal ArticleDOI
Recent Advances in the Synthesis of Indanes and Indenes
TLDR
The present Review is aimed at presenting some of the most important and innovative approaches to indanes and indenes that have been published in the course of the last ten years (coverage: from 2005 to May, 2015).Abstract:
Indanes and indenes are among the most important carbocycles. Many indane and indene derivatives have shown important pharmacological activities, and the indane and indene nuclei are structural motifs present in several natural products of biological relevance. In spite of their importance, only a few reviews on their preparation methods have appeared so far in the literature, the most recent ones being published about ten years ago. The present Review is aimed at filling this gap, presenting some of the most important and innovative approaches to indanes and indenes that have been published in the course of the last ten years (coverage: from 2005 to May, 2015).read more
Citations
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Journal ArticleDOI
Co(III)-Carbene Radical Approach to Substituted 1H-Indenes.
TL;DR: The metallo-radical catalyzed indene synthesis in this paper represents a unique example of a net (formal) intramolecular carbene insertion reaction into a vinylic C(sp(2))-H bond, made possible by a controlled radical ring-closure process of the carbene radical intermediate involved.
Journal ArticleDOI
GaCl3‐Mediated Reactions of Donor–Acceptor Cyclopropanes with Aromatic Aldehydes
TL;DR: A new strategy for cascade assembly of substituted indenes and polycyclic lactones based on reactions of donor-acceptor cyclopropanes and styrylmalonates with aromatic aldehydes in the presence of GaCl3 has been developed.
Journal ArticleDOI
Palladium‐Catalyzed Alkylation with Alkyl Halides by C(sp3)−H Activation
TL;DR: A two C-H alkylation system, initiated by the oxidative addition of organohalides to Pd0, has been developed, and provides a facile and efficient method for the synthesis of indanes.
Journal ArticleDOI
Gold(I)‐Catalyzed Synthesis of Indenes and Cyclopentadienes: Access to (±)‐Laurokamurene B and the Skeletons of the Cycloaurenones and Dysiherbols
TL;DR: The formal (3+2) cycloaddition between terminal allenes and aryl or styryl gold(I) carbenes generated by a retro‐Buchner reaction of 7‐substituted 1,3,5‐cycloheptatrienes led to indenes and cyclopentadienes, respectively.
Journal ArticleDOI
Enantioselective Intramolecular Reductive Heck Reaction with a Palladium/Monodentate Phosphoramidite Catalyst
Subramaniyan Mannathan,Saeed Raoufmoghaddam,Joost N. H. Reek,Johannes G. de Vries,Johannes G. de Vries,Adriaan J. Minnaard +5 more
TL;DR: In this paper, a palladium-catalyzed enantioselective reductive Heck reaction of enones using monodentate phosphoramidite ligands is described.
References
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Journal ArticleDOI
Gold-Catalyzed Organic Reactions
TL;DR: Important vinylgold intermediates, the transmetalation from gold to other transition metals, the development of new ligands for gold catalysis, and significant contributions from computational chemistry are other crucial points for the field highlighted here.
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Gold-catalyzed organic transformations.
Zigang Li,Chad Brouwer,Chuan He +2 more
TL;DR: Thanks to gold-based catalysts, various organic transformations have been accessible under facile conditions with both high yields and chemoselectivity.
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Alternative synthetic methods through new developments in catalysis by gold.
TL;DR: The results show clear trends in gold-Catalyzed C-H Bond Functionalization and Selective Reductions, and catalytic Hydrogenation of Alkenes and 1,3-Dienes, as well as in other areas of science.
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Indene−C60 Bisadduct: A New Acceptor for High-Performance Polymer Solar Cells
TL;DR: A new soluble C(60) derivative, indene-C( 60) bisadduct (ICBA), with a LUMO energy level 0.17 eV higher than that of PCBM is synthesized and indicates that ICBA is an alternative high-performance acceptor and could be widely used in high- performance PSCs.
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Gold-catalyzed carbon-heteroatom bond-forming reactions.
TL;DR: Application to Total Synthesis 1699 6.1.