Journal ArticleDOI
Recent Applications of Vinyl Sulfones and Vinyl Sulfoxides in Asymmetric Synthesis
Juan C. Carretero,Ramón Gómez Arrayás,Nuria Diaz Buezo,J. L. Garrido,Inés Alonso,Javier Adrio +5 more
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TLDR
In this article, the synthesis of castanospermine stereoisomers from ω-amino-γ-oxygenated-α and β-unsaturated sulfones with methylene active ketones is described.Abstract:
Herein we present some new synthetic applications based on the use of functionalized α,β-unsaturated sulfones and α,β-unsaturated sulfoxides. In particular, we have developed a stereodivergent approach to the synthesis of castanospermine stereoisomers from ω-amino-γ-oxygenated-α.β-unsaturated sulfones as well as a stereoselective synthesis of substituted dihydrofurans by Pd(0) catalyzed reaction of the carbonate derivatives of γ-oxygenated-α.β-unsaturated sulfones with methylene active ketones. Additionally, the use of the sulfinyl group as a novel chiral auxiliary in asymmetric Heck reactions is also described.read more
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Journal ArticleDOI
The chemistry of α, β-unsaturated sulfoxides and sulfones: an update
TL;DR: A comprehensive review of recent chemistry of α, β-unsaturated sulfoxides and sulfones is presented in this article, focusing on new reactions and strategies, stereo and enantio-selective reactions, and emerging areas of interest such as metal-mediated asymmetric synthesis, solid-phase organic synthesis (SPOS), and cascade or 'Domino' reactions.
Journal ArticleDOI
Separation of chiral sulfoxides by liquid chromatography using macrocyclic glycopeptide chiral stationary phases.
TL;DR: The macrocyclic glycopeptide CSPs provided broad selectivity and effective separations of chiral sulfoxides and it was shown that the polarity, volume and shape of the sulfoxide substituents influence the solute enantioselectivity factor.
Journal ArticleDOI
Vinyl sulfone-modified carbohydrates: an inconspicuous group of chiral building blocks
TL;DR: The synthesis and reactions of vinyl sulfone-modified pyranosides, furanosides and acyclic sugars, nucleosides and carbasugars are reviewed in this paper.
Journal ArticleDOI
Chemistry of electrochemical oxidative reactions of sulfinate salts
TL;DR: In this article, a review of recent achievements in the development of electrochemical transformations of sulfinate reagents has been presented and discussed, as well as insights into the reaction mechanism.
Book ChapterDOI
Sulfur is More Than the Fat Brother of Oxygen. An Overview of Organosulfur Chemistry
TL;DR: A survey of the structure and synthetic applications of organosulfur compounds is given in this article, where the emphasis is on the key features of organo-sulfur chemistry.
References
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Asymmetric Transition Metal-Catalyzed Allylic Alkylations.
TL;DR: The focus of this review is on the area of enantioselective transition metal-catalyzed allylic alkylations which may involve C-C as well as C-X (X ) H or heteroatom) bond formation.
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Allylic 1,3-strain as a controlling factor in stereoselective transformations
TL;DR: In this article, the authors present a model for controlling dyadic add-ion reactions to double-branched double-bond reactions, including the following: 1.3-Strain Control of Dlastereoselective Intermolecular Addhion Reactions InvoMng Heteroallyl Systems 10.5.
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Applications of Sulfoxides to Asymmetric Synthesis of Biologically Active Compounds
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Sulphones in organic synthesis
TL;DR: In this article, the authors discuss the precursory synthesis of sulphonyl carbanions, including simple alkyl and dialkyl synsets, and the reaction with epoxides.
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