Recommended Approaches to Minimize Aerosol Dispersion of SARS-CoV-2 During Noninvasive Ventilatory Support Can Cause Ventilator Performance Deterioration: A Benchmark Comparative Study.
Maxime Patout,Emeline Fresnel,Manuel Lujan,Claudio Rabec,Annalisa Carlucci,Léa Razakamanantsoa,Adrien Kerfourn,Hilario Nunes,Yacine Tandjaoui-Lambiotte,Antoine Cuvelier,Jean-François Muir,Cristina Lalmoda,Bruno Langevin,Javier Sayas,Jésus Gonzalez-Bermejo,Jean-Paul Janssens +15 more
TLDR
In this paper, the effects of various suggested circuit setups on ventilator efficacy during CPAP and non-invasive ventilation (NIV) were evaluated on a bench test model that consisted of a three-dimensional printed head and an artificial lung.About:
This article is published in Chest.The article was published on 2021-03-02 and is currently open access. It has received 16 citations till now. The article focuses on the topics: Tidal volume & Work of breathing.read more
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The use of head helmets to deliver noninvasive ventilatory support: a comprehensive review of technical aspects and clinical findings.
TL;DR: A helmet, comprising a transparent hood and a soft collar, surrounding the patient's head can be used to deliver non-invasive ventilatory support, both as continuous positive airway pressure and noninvasive positive pressure ventilation (NPPV), the latter providing active support for inspiration as discussed by the authors.
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COVID-19 Lessons Learned: Response to the Anticipated Ventilator Shortage
TL;DR: Early in the COVID-19 pandemic predictions of a worldwide ventilator shortage prompted a worldwide search for solutions as mentioned in this paper , and the United States government invoked the Defense Production Act to push automotive manufacturers to partner with existing ventilators manufacturers to speed production.
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Reorganizing the respiratory high dependency unit for pandemics.
TL;DR: In this article, the authors summarized the dual purpose of Respiratory High Dependency Units (RHDUs) and proposed an adaptation and optimization of the RHDUs to meet the emergent needs caused by the pandemic emphasizing the role of the expert application of noninvasive respiratory therapies in preventing intubation and ICU access.
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Higher mortality and intubation rate in COVID-19 patients treated with noninvasive ventilation compared with high-flow oxygen or CPAP
Sergi Marti,Anne-Elie Carsin,Julia Sampol,Mercedes Pallero,Irene Aldás,T. Marín,Manel Luján,Cristina Lalmolda,Gladis Sabater,Marc Bonnin-Vilaplana,Patricia Peñacoba,Juana Martínez-Llorens,Julia Tárrega,Oscar Bernadich,Ana Córdoba-Izquierdo,Lourdes Lozano,Susana Mendez,Eduardo Vélez-Segovia,Elena Prina,Saioa Eizaguirre,Ana Balañá-Corberó,Jaume Ferrer,Judith Garcia-Aymerich +22 more
TL;DR: In this article , the authors compared the effectiveness of non-invasive respiratory support in severe COVID-19 patients with high-flow oxygen administered via nasal cannula (HFNC), continuous positive airway pressure (CPAP) or noninvasive ventilation (NIV), initiated outside the intensive care unit (ICU) in 10 university hospitals in Catalonia, Spain.
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Quality versus emergency: How good were ventilation fittings produced by additive manufacturing to address shortages during the COVID19 pandemic?
Roman Hossein Khonsari,Mathilde Oranger,Pierre-Marc François,Alexis Mendoza-Ruiz,Karl Leroux,Ghilas Boussaid,Delphine Prieur,Jean-Pierre Hodge,Antoinette La Belle,Vincent Midler,Capucine Morélot-Panzini,Maxime Patout,Jésus Gonzalez-Bermejo +12 more
TL;DR: In this article , five 3D-printing designs were assessed for non-intentional (junctional and parietal) and intentional leaks: 4 fittings 3D printed in-house using FDeposition Modelling (FDM), 1 FDM 3Dprinting fitting provided by an independent maker, and 2 fittings3D-printed inhouse using Polyjet technology.
References
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COVID-19 Does Not Lead to a "Typical" Acute Respiratory Distress Syndrome.
Luciano Gattinoni,Silvia Coppola,Massimo Cressoni,Mattia Busana,Sandra Rossi,Davide Chiumello +5 more
TL;DR: It is found that hypercapnia was common in patients with COVID-19–associated ARDS while using low VT ventilation, and low VT may not be the best approach for all patients with ARDS, particularly those with a less severe decrease in respiratory system compliance and inadequacy of ventilation.
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Patient-ventilator asynchrony during assisted mechanical ventilation
TL;DR: One-fourth of patients exhibit a high incidence of asynchrony during assisted ventilation, which is associated with a prolonged duration of mechanical ventilation and with excessive levels of ventilatory support.
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Exhaled air dispersion during high-flow nasal cannula therapy versus CPAP via different masks.
David S.C. Hui,Benny K. Chow,Thomas Lo,Owen Tak-Yin Tsang,Fanny W.S. Ko,Susanna S.S. Ng,Tony Gin,Matthew T. V. Chan +7 more
TL;DR: Exhaled air dispersion from high-flow nasal cannula (HFNC) and CPAP is limited provided there is good mask interface fitting, however, exhaled air leakage to 620 mm laterally occurs when the connection between HFNC and the interface tube becomes loose.
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Evaluation of droplet dispersion during non-invasive ventilation, oxygen therapy, nebuliser treatment and chest physiotherapy in clinical practice: implications for management of pandemic influenza and other airborne infections
Anita K. Simonds,A. Hanak,Michelle Chatwin,Mary J. Morrell,A Hall,Kim H. Parker,Jennifer H. Siggers,Robert Julian Dickinson +7 more
TL;DR: The findings suggest that health-care workers providing NIV and chest physiotherapy, working within 1 m of an infected patient should have a higher level of respiratory protection, but that infection control measures designed to limit aerosol spread may have less relevance for these procedures.
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Feasibility and clinical impact of out-of-ICU noninvasive respiratory support in patients with COVID-19-related pneumonia.
C. Franco,Nicola Facciolongo,Roberto Tonelli,Roberto Dongilli,Andrea Vianello,Lara Pisani,Raffaele Scala,Mario Malerba,Annalisa Carlucci,Emanuele Alberto Negri,Greta Spoladore,Giovanna Arcaro,Paolo Amedeo Tillio,Cinzia Lastoria,Gioachino Schifino,Luca Tabbì,Luca Guidelli,Giovanni Guaraldi,V. Marco Ranieri,Enrico Clini,Stefano Nava +20 more
TL;DR: In patients with SARS-CoV-2 infection and acute respiratory failure, this study demonstrates that the utilisation of noninvasive respiratory support delivered outside the ICU was feasible and effective, but associated with a risk of staff contamination.