Recovery of laryngeal function after intraoperative injury to the recurrent laryngeal nerve
TLDR
This review aims to provide an update on the current understandings of surgically-induced injury to the laryngeal nerves to clarify any differences between the transient and permanent injury of the RLN.Abstract:
Loss of function in the recurrent laryngeal nerve (RLN) during thyroid/parathyroid surgery, despite a macroscopically intact nerve, is a challenge which highlights the sensitivity and complexity of laryngeal innervation. Furthermore, the uncertain prognosis stresses a lack of capability to diagnose the reason behind the impaired function. There is a great deal of literature considering risk factors, surgical technique and mechanisms outside the nerve affecting the incidence of RLN paresis during surgery. To be able to prognosticate recovery in cases of laryngeal dysfunction and voice changes after thyroid surgery, the surgeon would first need to define the presence, location, and type of laryngeal nerve injury. There is little data describing the events within the nerve and the neurobiological reasons for the impaired function related to potential recovery and prognosis. In addition, very little data has been presented in order to clarify any differences between the transient and permanent injury of the RLN. This review aims, from an anatomical and neurobiological perspective, to provide an update on the current understandings of surgically-induced injury to the laryngeal nerves.read more
Citations
More filters
Journal ArticleDOI
Degeneration and regeneration of the nervous system
Journal ArticleDOI
Electrodiagnosis in Diseases of Nerve and Muscle: Principles and Practice
TL;DR: This 672-page volume written by a single author contains 26 chapters in seven parts and three appendices and is intended for practicing electromyographers and all those concerned with electrodiagnostic tests in clinical practice.
Journal ArticleDOI
The Physiologic Impact of Unilateral Recurrent Laryngeal Nerve (RLN) Lesion on Infant Oropharyngeal and Esophageal Performance
Francois D. H. Gould,Andrew R. Lammers,Jocelyn Ohlemacher,Ashley Ballester,Luke Fraley,Andrew Gross,Rebecca Z. German +6 more
TL;DR: The results indicate that RLN lesion leads to increased frequency of aspiration, and increased esophageal dysfunction, with significant variation in these basic patterns at all levels, and suggests that neurological variation underlies this pattern.
Journal ArticleDOI
Timing of Nimodipine Therapy for the Treatment of Vocal Fold Paralysis
TL;DR: To retrospectively determine optimal timing for initiation of nimodipine within a cohort of patients with acute vocal fold paralysis, data are presented on patients diagnosed with VFP in the 1990s.
Journal ArticleDOI
Application of transoral continuous intraoperative neuromonitoring in natural orifice transluminal endoscopic surgery for thyroid disease: a preliminary study.
TL;DR: Cont-IONM is feasible and safe to use during transoral endoscopic thyroidectomies and may assist in the early detection of adverse EMG changes, thereby preventing paralysis of the RLNs.
References
More filters
Journal ArticleDOI
Nimodipine-induced improved survival rate of facial motor neurons following intracranial transection of the facial nerve in the adult rat
TL;DR: A neuroprotective role for nimodipine is proposed, which may be useful as a "cranial nerve protective agent" following insults such as head injury or skull base surgery.
Journal ArticleDOI
Diagnosis and prognosis of iatrogenic injury of the recurrent laryngeal nerve.
TL;DR: The results show that laryngeal electromyography is a reliable tool for diagnosing the type of injury within the injured RLN, making it possible to predict the functional outcome in patients with acute postoperative unilateral RLN paralysis.
Journal ArticleDOI
Continuous monitoring of the recurrent laryngeal nerve in thyroid surgery: a critical appraisal
Gianlorenzo Dionigi,Gianluca Donatini,Luigi Boni,Stefano Rausei,Francesca Rovera,Maria Laura Tanda,Hoon Yub Kim,Feng-Yu Chiang,Che-Wei Wu,Alberto Mangano,Francesco Rulli,Piero F. Alesina,Renzo Dionigi +12 more
TL;DR: C-IONM is useful to prevent the imminent traction injury by detecting progressive decreases in electromyographic amplitude combined with progressive latency increases and seems to be a technological improvement.
Journal ArticleDOI
Superior laryngeal nerve injury: effects, clinical findings, prognosis, and management options.
TL;DR: Subtle signs, symptoms, and diagnostic findings associated with SLNp make this disorder difficult to characterize clinically, and lack of treatment methodologies to restore the dynamic action of the cricothyroid muscles poses difficulties in treating patients with this condition.
Journal ArticleDOI
Nimodipine improves reinnervation and neuromuscular function after injury to the recurrent laryngeal nerve in the rat.
TL;DR: Nimodipine improves regeneration and neuromuscular function following RLN injury in the adult rat, and could be of use in future strategies followingRLN injury.
Related Papers (5)
Electrophysiological neural monitoring of the laryngeal nerves in thyroid surgery: review of the current literature.
Electrophysiologic recurrent laryngeal nerve monitoring during thyroid and parathyroid surgery: international standards guideline statement.
Gregory W. Randolph,Gregory W. Randolph,Henning Dralle,Hisham Abdullah,Marcin Barczyński,Rocco Domenico Alfonso Bellantone,Michael Brauckhoff,Bruno Carnaille,Sergii Cherenko,Fen‐Yu Chiang,Gianlorenzo Dionigi,Camille Finck,Dana M. Hartl,Dipti Kamani,Kerstin Lorenz,Paolo Miccolli,Radu Mihai,Akira Miyauchi,Lisa A. Orloff,Nancy D. Perrier,Manuel C Durán Poveda,Anatoly Romanchishen,Jonathan W. Serpell,Antonio Sitges-Serra,Tod Sloan,Sam Van Slycke,Samuel K. Snyder,Hiroshi Takami,Erivelto Volpi,Gayle E. Woodson +29 more