Red blood cell membrane-camouflaged nanoparticles: a novel drug delivery system for antitumor application.
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TLDR
In this review, the biomimetic platform of erythrocyte membrane-coated nano-cores is described with regard to various aspects, with particular focus placed on the coating mechanism, preparation methods, verification methods, and the latest anti-tumor applications.About:
This article is published in Acta Pharmaceutica Sinica B.The article was published on 2019-01-24 and is currently open access. It has received 301 citations till now. The article focuses on the topics: Membrane & Drug delivery.read more
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The Importance of Poly(ethylene glycol) Alternatives for Overcoming PEG Immunogenicity in Drug Delivery and Bioconjugation.
Thai Thanh Hoang Thi,Emily H. Pilkington,Dai Hai Nguyen,Jung Seok Lee,Ki Dong Park,Nghia P. Truong +5 more
TL;DR: Recent literature is collated to draw the attention of polymer chemists to the issue of PEG immunogenicity in drug delivery and bioconjugation, thereby highlighting the importance of developing alternative polymers to replace PEG.
Journal ArticleDOI
The versatile biomedical applications of bismuth-based nanoparticles and composites: therapeutic, diagnostic, biosensing, and regenerative properties
Mohammad-Ali Shahbazi,Mohammad-Ali Shahbazi,Leila Faghfouri,Mónica P. A. Ferreira,Patrícia Figueiredo,Hajar Maleki,Farshid Sefat,Jouni Hirvonen,Hélder A. Santos +8 more
TL;DR: This review emphasizes the synthesis and state-of-the-art progress related to the biomedical applications of BiNPs with different structures, sizes, and compositions.
Journal ArticleDOI
Recent Advances in Understanding the Protein Corona of Nanoparticles and in the Formulation of "Stealthy" Nanomaterials.
TL;DR: The latest advances in the characterization of PC, development of stealthy NP formulations, as well as the manipulation and employment of PC as an alternative resource for prolonging NP half-life are discussed, aswell as its use in diagnostic applications.
Journal ArticleDOI
Cell Membrane Coating Technology: A Promising Strategy for Biomedical Applications
TL;DR: This review provides a comprehensive overview of the theory of cell membrane coating technology, followed by a summary of the existing preparation and characterization techniques, and focuses on the functions and applications of various cell membrane types.
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Hybrid cell membrane-coated nanoparticles: A multifunctional biomimetic platform for cancer diagnosis and therapy.
TL;DR: This paper summarized recent progress on the hybrid cell membrane-camouflaged nanoparticles as drug delivery systems for cancer diagnosis and treatment with the preparation strategies, the camouflaging mechanism, and the antitumor applications.
References
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Nanocarriers as an emerging platform for cancer therapy
Dan Peer,Jeffrey M. Karp,Jeffrey M. Karp,Seungpyo Hong,Omid C. Farokhzad,Rimona Margalit,Robert Langer +6 more
TL;DR: The arsenal of nanocarriers and molecules available for selective tumour targeting, and the challenges in cancer treatment are detailed and emphasized.
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Nanoparticle therapeutics: an emerging treatment modality for cancer
TL;DR: The features of nanoparticle therapeutics that distinguish them from previous anticancer therapies are highlighted, and how these features provide the potential for therapeutic effects that are not achievable with other modalities are described.
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Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles
TL;DR: This work has shown that addition of PEG and PEG-containing copolymers to the surface of nanoparticles results in an increase in the blood circulation half-life of the particles by several orders of magnitude, and creates a hydrophilic protective layer around the nanoparticles that is able to repel the absorption of opsonin proteins via steric repulsion forces.
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Effect of pegylation on pharmaceuticals
J. Milton Harris,Robert B. Chess +1 more
TL;DR: How PEGylation can result in drugs that are often more effective and safer, and which show improved patient convenience and compliance are reviewed.
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The golden age: gold nanoparticles for biomedicine
TL;DR: It is argued that gold nanotechnology-enabled biomedicine is not simply an act of 'gilding the (nanomedicinal) lily', but that a new 'Golden Age' of biomedical nanotechnology is truly upon us.
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