Journal ArticleDOI
Release of prostaglandins E and F in an algogenic reaction and its inhibition.
TLDR
An examination of cells collected by washing the peritoneum revealed a large decrease between 15 and 30 min after injection of the irritant, which suggested that the prostaglandins could be produced by neutrophil polynuclear cells but also by destruction of macrophages.About:
This article is published in European Journal of Pharmacology.The article was published on 1980-01-11. It has received 742 citations till now. The article focuses on the topics: Prostaglandin E & Prostaglandin.read more
Citations
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Visceral pain: a review of experimental studies.
Timothy J. Ness,G.F. Gebhart +1 more
TL;DR: This paper proposes a definition of an adequate noxious visceral stimulus and speculate on spinal mechanisms of visceral pain, and reviews clinical and basic science research reports on visceral pain.
Journal ArticleDOI
Phytochemicals and uses of Moringa oleifera leaves in Ugandan rural communities.
TL;DR: The results validate the traditional use of this plant and zerumbone has been demonstrated to be a potent anti-inflammatory and analgesic agent.
Journal ArticleDOI
Antinociceptive and Antioxidant Activities of Phytol In Vivo and In Vitro Models.
Camila Carolina de Menezes Patrício Santos,Mirian Graciela da Silva Stiebbe Salvadori,Vanine Gomes Mota,Luciana Muratori Costa,Antonia Amanda Cardoso de Almeida,Guilherme Antônio Lopes de Oliveira,Jéssica Pereira Costa,Damião Pergentino de Sousa,Rivelilson Mendes de Freitas,Reinaldo Nóbrega de Almeida +9 more
TL;DR: Taken as a whole, these results show the pronounced antinociceptive effects of phytol in the nociception models used, both through its central and peripheral actions, but also its antioxidant properties demonstrated in the in vitro methods used.
Journal ArticleDOI
Pomegranate as a cosmeceutical source: pomegranate fractions promote proliferation and procollagen synthesis and inhibit matrix metalloproteinase-1 production in human skin cells.
TL;DR: Heuristic potential of pomegranate fractions for facilitating skin repair in a polar manner is suggested, namely aqueous extracts (especially of pembrokeshire peel) promoting regeneration of dermis, and pome Granatum seed oil promotes regeneration of epidermis.
Journal ArticleDOI
Evaluation of the analgesic effect of alkaloid extract of Peganum harmala L.: possible mechanisms involved.
TL;DR: The alkaloid extract of Peganum harmala seems to have both central and peripheral antinociceptive activities which may be mediated by opioid receptors.
References
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Journal ArticleDOI
Prostaglandins, aspirin-like drugs and analgesia.
TL;DR: Compared the pain producing activity of fatty acid hydroperoxides with that of high concentrations of acetylcholine, bradykinin, histamine and PGE1 on intradermal injection in man, the intensity of the pain induced was greater than that induced by the other agonists but for all except P GE1 the pain was transitory.
Journal ArticleDOI
Macrophages synthesise and release prostaglandins in response to inflammatory stimuli
John L. Humes,R. J. Bonney,Louis Pelus,Mary Ellen Dahlgren,Sharon Sadowski,Frederick A. Kuehl,P. Davies +6 more
TL;DR: It is shown that macrophages whose phospholipid components were labelled with3H-arachidonic acid also synthesise and release 3H-prostaglandins (PGs) in response to inflammatory stimuli, consistent with the findings that human Macrophages on intrauterine devices and guinea pig macrophage responding to lymphokines release PGs.
Journal ArticleDOI
Prostaglandin E production by human blood monocytes and mouse peritoneal macrophages.
JI Kurland,Richard S. Bockman +1 more
TL;DR: Findings indicate that the blood monocyte and tissue macrophage represent an important source of prostaglandin E, a function shared by both normal and neoplastic mononuclear phagocytes.
Journal ArticleDOI
Radioimmunoassay of Prostaglandins Fα, E1 and E2 in Human Plasma
TL;DR: Antibodies against prostaglandins were obtained in rabbits immunized with respectively PG F2α, PG E1 and PG E2 conjugated to bovine serum albumin by carbodiimide.
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