Reliability and Comparability of Psychosis Patients’ Retrospective Reports of Childhood Abuse
Helen L. Fisher,Tom K. J. Craig,Paul Fearon,Kevin Morgan,Paola Dazzan,Paola Dazzan,Julia Lappin,Gerard Hutchinson,Gillian A. Doody,Peter B. Jones,Peter McGuffin,Robin M. Murray,Robin M. Murray,Julian Leff,Craig Morgan,Craig Morgan +15 more
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TLDR
The reliability and comparability of first-presentation psychosis patients' reports of childhood abuse are explored and justification for the use in future studies of retrospective reports of Childhood abuse obtained from individuals with psychotic disorders is provided.Abstract:
An increasing number of studies are demonstrating an association between childhood abuse and psychosis. However, the majority of these rely on retrospective self-reports in adulthood that may be unduly influenced by current psychopathology. We therefore set out to explore the reliability and comparability of first-presentation psychosis patients’ reports of childhood abuse. Psychosis case subjects were drawn from the Aetiology and Ethnicity of Schizophrenia and Other Psychoses (AESOP) epidemiological study and completed the Childhood Experience of Care and Abuse Questionnaire to elicit abusive experiences that occurred prior to 16 years of age. High levels of concurrent validity were demonstrated with the Parental Bonding Instrument (antipathy: rs = 0.350–0.737, P < .001; neglect: rs = 0.688–0.715, P < .001), and good convergent validity was shown with clinical case notes (sexual abuse: κ = 0.526, P < .001; physical abuse: κ = 0.394, P < .001). Psychosis patients’ reports were also reasonably stable over a 7-year period (sexual abuse: κ = 0.590, P < .01; physical abuse: κ = 0.634, P < .001; antipathy: κ = 0.492, P < .01; neglect: κ = 0.432, P < .05). Additionally, their reports of childhood abuse were not associated with current severity of psychotic symptoms (sexual abuse: U = 1768.5, P = .998; physical abuse: U = 2167.5, P = .815; antipathy: U = 2216.5, P = .988; neglect: U = 1906.0, P = .835) or depressed mood (sexual abuse: χ2 = 0.634, P = .277; physical abuse: χ2 = 0.159, P = .419; antipathy: χ2 = 0.868, P = .229; neglect: χ2 = 0.639, P = .274). These findings provide justification for the use in future studies of retrospective reports of childhood abuse obtained from individuals with psychotic disorders.read more
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The impact of childhood trauma on cognitive functioning in patients recently recovered from a first manic episode: data from the Systematic Treatment Optimization Program for Early Mania (STOP-EM).
Joana Bücker,Jan-Marie Kozicky,Ivan J. Torres,Márcia Kauer-Sant'Anna,Leonardo Evangelista da Silveira,Leonardo Evangelista da Silveira,David J. Bond,Raymond W. Lam,Lakshmi N. Yatham +8 more
TL;DR: The results require replication, but suggest that the co-occurrence of trauma and bipolar disorder can affect those cognitive areas that are already more susceptible in patients with BD.
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Negative life events and corticotropin-releasing-hormone receptor1 gene in recurrent major depressive disorder
Zhongchun Liu,Wanhong Liu,Lihua Yao,Can Yang,Ling Xiao,Qirong Wan,Kai Gao,Huiling Wang,Fan Zhu,Gaohua Wang,Zheman Xiao +10 more
TL;DR: It is suggested that the CRHR1 gene could modify the susceptibility to developing recurrent MDD following negative life events in adulthood, as a major mediator of the stress response.
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Childhood adversity and conduct disorder: A developmental pathway to violence in schizophrenia
Clare Oakley,Clare Oakley,Stephanie T. Harris,Stephanie T. Harris,Thomas Fahy,Declan G. Murphy,Marco Picchioni,Marco Picchioni +7 more
TL;DR: Results indicate a complex interplay between childhood adversity, conduct disorder and later violent behaviour in schizophrenia, and suggest that there may be shared aetiological risk factors on a common developmental pathway to violence.
Journal ArticleDOI
Concordance between mother and offspring retrospective reports of childhood adversity.
TL;DR: This study aimed to explore whether maternal retrospective reports of childhood adversity were concordant with those provided directly by their offspring as part of a larger investigation of intergenerational transmission of risk for depression.
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Childhood maltreatment and comorbid anxiety in people with bipolar disorder.
Barbara Pavlova,Barbara Pavlova,Nader Perroud,Paolo Cordera,Rudolf Uher,Rudolf Uher,Alexandre Dayer,Jean-Michel Aubry +7 more
TL;DR: Exposure to maltreatment in childhood is associated with comorbid anxiety disorders among individuals living with bipolar disorder and may constitute a separate aetiological type with a greater contribution of early environment.
References
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