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Alexandre Dayer

Researcher at University of Geneva

Publications -  123
Citations -  5468

Alexandre Dayer is an academic researcher from University of Geneva. The author has contributed to research in topics: Bipolar disorder & Corticogenesis. The author has an hindex of 37, co-authored 115 publications receiving 4529 citations. Previous affiliations of Alexandre Dayer include University of Strasbourg & Manchester Metropolitan University.

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Regulation of adult neurogenesis by stress, sleep disruption, exercise and inflammation: Implications for depression and antidepressant action

TL;DR: It is concluded that a lasting reduction in neurogenesis following severe or chronic stress exposure, either in adult or early life, may represent impaired hippocampal plasticity and can contribute to the cognitive symptoms of depression, but is, by itself, unlikely to produce the full mood disorder.
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Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study

Liping Hou, +136 more
- 12 Mar 2016 - 
TL;DR: A genome-wide association study of lithium response in 2,563 patients collected by 22 participating sites from the International Consortium on Lithium Genetics (ConLiGen); the largest attempted so far finds a single locus of four linked SNPs on chromosome 21 met genome- wide significance criteria for association with lithium response.
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Sequential transcriptional waves direct the differentiation of newborn neurons in the mouse neocortex.

TL;DR: Early transcriptional waves that instruct the sequence and pace of neuronal differentiation events, guiding newborn neurons toward their final fate, and contribute to a road map for the reverse engineering of specific classes of cortical neurons from undifferentiated cells are revealed.
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Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex.

TL;DR: A core set of evolutionarily conserved, temporally patterned genes that sequentially unfold during development are identified that drive apical progenitors from internally directed to more exteroceptive (“extraverted”) states.
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Volatile anesthetics rapidly increase dendritic spine density in the rat medial prefrontal cortex during synaptogenesis.

TL;DR: In this article, exposure time-dependent effects of volatile anesthetics on neuronal cytoarchitecture in 16-day-old rats, a developmental stage characterized by intense synaptogenesis in the cerebral cortex, were evaluated.