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Journal ArticleDOI

Response surface methodology (RSM) as a tool for optimization in analytical chemistry

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TLDR
A review about the application of response surface methodology (RSM) in the optimization of analytical methods is presented and the theoretical principles and steps for its application are described to introduce readers to this multivariate statistical technique.
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This article is published in Talanta.The article was published on 2008-09-15. It has received 4338 citations till now. The article focuses on the topics: Response surface methodology & Central composite design.

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Journal ArticleDOI

Experimental design and multiple response optimization. Using the desirability function in analytical methods development

TL;DR: A review about the application of response surface methodology (RSM) when several responses have to be simultaneously optimized in the field of analytical methods development is presented.
Journal ArticleDOI

Nano-selenium and its nanomedicine applications: a critical review.

TL;DR: This review summarizes the survey of knowledge on selenium nanoparticles, their biological effects in the organism, advantages, absorption mechanisms, and nanotechnological applications for peroral administration and explores the possibilities of a more effective way of administration, especially in seenium-deficient organisms.
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Nanoemulsion as pharmaceutical carrier for dermal and transdermal drug delivery: Formulation development, stability issues, basic considerations and applications.

TL;DR: This article reviews the progressive advancement in the delivery of medicament via nanoemulsion with special reference to the dermal and transdermal administration and attempted to explore the most suitable semi solid dosage form for the particular type of nanoemulsions.
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Enhanced extraction of bioactive natural products using tailor-made deep eutectic solvents: application to flavonoid extraction from Flos sophorae

TL;DR: In this article, the authors presented a practical example using a popular traditional Chinese medicine, Flos sophorae, showcasing the tuneability of DESs as designer solvents to selectively and efficiently extract bioactive compounds from biomass.
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Photocatalytic degradation using design of experiments: a review and example of the Congo red degradation.

TL;DR: The present article reviews the major applications of RSM in modern experimental design combined with photocatalytic degradation processes and the theoretical principles and designs that enable to obtain a polynomial regression equation are thoroughly discussed.
References
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Journal ArticleDOI

Box-Behnken design: An alternative for the optimization of analytical methods

TL;DR: The present paper describes fundamentals, advantages and limitations of the Box-Behnken design for the optimization of analytical methods, and establishes also a comparison between this design and composite central, three-level full factorial and Doehlert designs.
Journal ArticleDOI

Modeling and optimization I: Usability of response surface methodology

TL;DR: This paper looked at some of the RSM articles published during the last few years to identify common mistakes made in the application and the limitations of RSM.
Book

Chemometrics: Statistics and Computer Application in Analytical Chemistry

Matthias Otto
TL;DR: This book provides comprehensive and state-of-the-art coverage of chemometrics including such important areas as knowledge processing, handling analytical data bases, natural computations, fuzzy theory, and quality assurance.
Book

Statistical design--chemometrics

TL;DR: This chapter discusses statistics, modeling, and optimization in the context ofixtures modeling, where there are many variables and the response surface is very large.
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