Journal ArticleDOI
Risk factors for mortality after surgery in patients with cirrhosis.
Swee H. Teh,David M. Nagorney,Susanna R. Stevens,Kenneth P. Offord,Terry M. Therneau,David J. Plevak,Jayant A. Talwalkar,W. Ray Kim,Patrick S. Kamath +8 more
TLDR
MELD score, age, and American Society of Anesthesiologists class can quantify the risk of mortality postoperatively in patients with cirrhosis, independently of the procedure performed and can be used in determining operative mortality risk and whether elective surgical procedures can be delayed until after liver transplantation.About:
This article is published in Gastroenterology.The article was published on 2007-04-01. It has received 438 citations till now. The article focuses on the topics: Risk of mortality & Model for End-Stage Liver Disease.read more
Citations
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Journal ArticleDOI
Hepatosplanchnic circulation in cirrhosis and sepsis
TL;DR: An overview of the hepatosplanchnic circulation in the healthy state and in Cirrhosis is provided, the signaling pathways that may play a role in the physiology of cirrhosis are examined, and the physiology common to cir rhosis and sepsis is discussed.
Journal ArticleDOI
Incidence and Risk Factors of Postoperative Mortality and Morbidity After Elective Versus Emergent Abdominal Surgery in a National Sample of 8193 Patients With Cirrhosis
Kay M. Johnson,Kay M. Johnson,Kira L. Newman,Pamela Green,Kristin Berry,Paul B. Cornia,Paul B. Cornia,Peter K. Wu,Lauren A. Beste,Lauren A. Beste,Kamal M.F. Itani,Alex H. S. Harris,Alex H. S. Harris,Patrick S. Kamath,George N. Ioannou,George N. Ioannou +15 more
TL;DR: Accurate preoperative risk assessments in patients with Cirrhosis should account for cirrhosis severity, comorbidities, type of procedure, and whether the procedure is emergent versus elective.
Journal ArticleDOI
New Pharmacologic Therapies in Gastrointestinal Disease
John L. Wallace,Jose G. Ferraz +1 more
TL;DR: This article is focused on drugs for digestive disorders that have entered the marketplace recently, or are expected to reach the marketplace within the next 1 to 2 years.
Journal ArticleDOI
Selecting a short-term prognostic model for hepatocellular carcinoma: comparison between the model for end-stage liver disease (MELD), MELD-sodium, and five cancer staging systems.
Teh Ia Huo,Cheng Yuan Hsia,Yi Hsiang Huang,Han-Chieh Lin,Pui Ching Lee,Wing Yiu Lui,Jen Huei Chiang,Yi You Chiou,Che Chuan Loong,Shou-Dong Lee +9 more
TL;DR: The MELD-Na may improve the prognostic ability of the MELD system for patients with HCC, and both the CLIP and Tokyo systems are better short-term prognostic models.
Journal ArticleDOI
On-Treatment Improvement of MELD Score Reduces Death and Hepatic Events in Patients With Hepatitis B-Related Cirrhosis.
Terry Cheuk-Fung Yip,Henry Lik-Yuen Chan,Yee-Kit Tse,Kelvin Long-Yan Lam,Grace Lui,Vincent Wai-Sun Wong,Grace Lai-Hung Wong +6 more
TL;DR: On‐treatment improvement of MELD score correlates with reduced risk of mortality and hepatic events in cirrhotic CHB patients, as reflected by improving Model for End‐Stage Liver Disease (MELD) score over time.
References
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Journal ArticleDOI
A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation☆
TL;DR: The method of classifying comorbidity provides a simple, readily applicable and valid method of estimating risk of death fromComorbid disease for use in longitudinal studies and further work in larger populations is still required to refine the approach.
Book
Modeling Survival Data: Extending the Cox Model
TL;DR: A Cox Model-based approach was used to estimate the Survival and Hazard Functions and the results confirmed the need for further investigation into the role of natural disasters in shaping survival rates.
Journal ArticleDOI
A model to predict survival in patients with end‐stage liver disease
Patrick S. Kamath,Russell H. Wiesner,Michael Malinchoc,Walter K. Kremers,Terry M. Therneau,Catherine L. Kosberg,Gennaro D'Amico,E. Rolland Dickson,M.B.A. W. Ray Kim M.D. +8 more
TL;DR: The MELD scale is a reliable measure of mortality risk in patients with end‐stage liver disease and suitable for use as a disease severity index to determine organ allocation priorities in patient groups with a broader range of disease severity and etiology.
Journal ArticleDOI
A model to predict poor survival in patients undergoing transjugular intrahepatic portosystemic shunts.
Michael Malinchoc,Patrick S. Kamath,Fredric D. Gordon,Craig J. Peine,Jeffrey M. Rank,Pieter C.J. ter Borg +5 more
TL;DR: This Mayo TIPS model may predict early death following elective TIPS for either prevention of variceal rebleeding or for treatment of refractory ascites, superior to both the Child‐Pugh classification and the Child-Pugh score in predicting survival.
Journal ArticleDOI
Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies.
TL;DR: The natural history of cirrhosis is outlined, the model for end stage liver disease (MELD) has replaced the Child–Pugh score in the United States for prioritizing liver donor allocation and a systematic review of the literature regarding predictors of mortality in cirrhotic patients is reported on.