Journal ArticleDOI
Role of polyunsaturated fatty acids in the management of Egyptian children with autism.
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TLDR
PUFA supplementation may play an important role in ameliorating the autistic behavior and linolenic acid and docosahexaenoic acid showed the highest levels after Efalex supplementation.About:
This article is published in Clinical Biochemistry.The article was published on 2008-09-01. It has received 118 citations till now. The article focuses on the topics: Docosahexaenoic acid & Linoleic acid.read more
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Functional Roles of Fatty Acids and Their Effects on Human Health
TL;DR: It would seem more appropriate to describe biological effects and health impacts of individual named fatty acids, although it is recognized that this would be a challenge when communicating outside of an academic environment (eg, to consumers).
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Long-chain polyunsaturated fatty acids (LCPUFA) from genesis to senescence: The influence of LCPUFA on neural development, aging, and neurodegeneration
TL;DR: This review shows that LCPUFA are essential throughout life, especially for neuronal membrane integrity and function, and also contribute in prevention of brain hypoperfusion.
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Short-chain fatty acid fermentation products of the gut microbiome: implications in autism spectrum disorders.
TL;DR: Gut-derived factors, such as dietary or enteric bacterially produced SCFAs, may be plausible environmental agents that can trigger ASDs or ASD-related behaviors and deserve further exploration in basic science, agriculture, and clinical medicine.
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Arachidonic acid: Physiological roles and potential health benefits - A review.
TL;DR: Arachidonic acid is an integral constituent of biological cell membrane, conferring it with fluidity and flexibility, so necessary for the function of all cells, especially in nervous system, skeletal muscle, and immune system.
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Vitamin D hormone regulates serotonin synthesis. Part 1: relevance for autism
Rhonda P. Patrick,Bruce N. Ames +1 more
TL;DR: Evidence is presented that vitamin D hormone (calcitriol) activates the transcription of the serotonin‐synthesizing gene tryptophan hydroxylase 2 (TPH2) in the brain at a vitamin D response element (VDRE) and represses thecription of TPH1 in tissues outside the blood‐brain barrier at a distinct VDRE.
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Epidemiological surveys of autism and other pervasive developmental disorders: an update.
TL;DR: There is evidence that changes in case definition and improved awareness explain much of the upward trend of rates in recent decades, however, available epidemiological surveys do not provide an adequate test of the hypothesis of a changing incidence of PDDs.
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The essentiality of long chain n-3 fatty acids in relation to development and function of the brain and retina.
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Autism: Towards an Integration of Clinical, Genetic, Neuropsychological, and Neurobiological Perspectives
TL;DR: A partial integration of the causal processes leading to autism requires an integration across different levels of enquiry, and provides a useful strategy for identifying key research questions, the limitations of existing hypotheses, and future research directions that are likely to prove fruitful.
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Are long-chain polyunsaturated fatty acids essential nutrients in infancy?
TL;DR: DHA seems to be an essential nutrient for the optimum neural maturation of term infants as assessed by VEP acuity since infants breastfed for short periods had slower development of VEP than infants receiving a continuous supply of DHA from either breastmilk or supplemented formula.