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Journal ArticleDOI

Role of the pericyte in wound healing: An ultrastructural study☆

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TLDR
It is proposed that the pericyte-endothelial “contacts” act as a regulatory mechanism for capillary proliferation.
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This article is published in Experimental and Molecular Pathology.The article was published on 1970-08-01. It has received 213 citations till now. The article focuses on the topics: Pericyte & Wound healing.

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Comparison of the effects of moist and dry conditions on the process of angiogenesis during dermal repair.

TL;DR: In general, moist wounds showed a more rapid decline towards uninjured skin levels of vascularization than dry wounds, suggesting that the vessels in the moist wounds were larger and, presumably, more mature.
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Pericytes, Mesenchymal Stem Cells and the Wound Healing Process

TL;DR: The most recent data on pericytes, particularly their role in vessel formation and how they can affect the wound healing process are collated.
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The effect of endothelin 1 on the retinal microvascular pericyte.

TL;DR: Observations suggest that ET1 may play an important role in endothelial cell-pericyte interactions within the microvasculature of the retina and that it may be involved in the autoregulation of retinal blood flow.
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Similarities in the phenotypic expression of pericytes and bone cells.

TL;DR: Findings show that the microvessel pericyte is capable of exhibiting several oxygen dependent, phenotypic characteristics ascribed to osteoblasts, which are similar to those found in bone cells and pericytes.
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An experimental model to investigate the dynamics of wound contraction

TL;DR: An excisional wound model in the Hooded Lister rat is described and is shown to be reliable, reproducible and capable of detecting the effect of systemically administered prednisolone.
References
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THE USE OF LEAD CITRATE AT HIGH pH AS AN ELECTRON-OPAQUE STAIN IN ELECTRON MICROSCOPY

TL;DR: The stain reported here differs from previous alkaline lead stains in that the chelating agent, citrate, is in sufficient excess to sequester all lead present, and is less likely to contaminate sections.
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Staining of Tissue Sections for Electron Microscopy with Heavy Metals

TL;DR: Certain hitherto unobserved details are revealed and some sort of specificity exists, although the factors involved are not yet understood.
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Cytochemistry and electron microscopy. The preservation of cellular ultrastructure and enzymatic activity by aldehyde fixation.

TL;DR: A postfixation in osmium tetroxide, even after long periods of storage, developed an image that—notable in the case of glutaraldehyde—was largely indistinguishable from that of tissues fixed under optimal conditions with osmia tetroxides alone.
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A method for staining epoxy sections for light microscopy.

TL;DR: A technique for staining sections of osmium-fixed, epoxy-embedded tissues for light microscopy using aqueous toluidine blue at pH 11.1 and does not require prior removal of embedding medium, which permits better utilization of the full resolving power of the light microscope.
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The initiation of cell division in a contact-inhibited mammalian cell line.

TL;DR: The sequence of event suggests that regulation of RNA synthesis is the means by which contact inhibition controls cell division, and therefore DNA synthesis and cell division are controlled.
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