Journal ArticleDOI
Role of the pericyte in wound healing: An ultrastructural study☆
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TLDR
It is proposed that the pericyte-endothelial “contacts” act as a regulatory mechanism for capillary proliferation.About:
This article is published in Experimental and Molecular Pathology.The article was published on 1970-08-01. It has received 213 citations till now. The article focuses on the topics: Pericyte & Wound healing.read more
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The enigmatic role of angiopoietin-1 in tumor angiogenesis
TL;DR: An increasing amount of experimental data suggest that Ang1-stimulated association of mural cells with endothelial cells lead to stabilization of newly formed blood vessels, which may limit the otherwise continuous angiogenesis in the tumor, and consequently give rise to inhibition of tumor growth.
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Vascular development and disorders : Molecular analysis and pathogenic insights
Peter Carmeliet,Desire Collen +1 more
TL;DR: Investigation into the molecular mechanisms that regulate the development and function of both endothelial and pericyte/smooth muscle cells has become a major focus in vascular biology and a number of candidate molecules have been identified that stimulate or inhibit these processes.
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Capillary pericytes: Perspectives and future trends
TL;DR: The development of new electron microscopy techniques and the application of new cell culture and molecular biology techniques should allow for the rapid elucidation of the cellular biochemistry and the microvascular function and pathology of this ubiquitous capillary cell.
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Activation of microvascular pericytes in autoimmune Raynaud's phenomenon and systemic sclerosis.
TL;DR: The findings suggest that features of autoimmune RP are distinct from those of primary RP, and that microv vascular pericytes may be an important link between chronic microvascular damage and fibrosis.
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Clonal heterogeneity in fibroblast phenotype: Implications for the control of epithelial-mesenchymal interactions
Seth L. Schor,Ana M. Schor +1 more
TL;DR: The widespread distribution of fibroblasts underlines their central role in mammalian physiology, development and ageing and their relative proportion and tissue distribution must have important consequences in the control of connective tissue and adjacent epithelial functions in health and disease.
References
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THE USE OF LEAD CITRATE AT HIGH pH AS AN ELECTRON-OPAQUE STAIN IN ELECTRON MICROSCOPY
TL;DR: The stain reported here differs from previous alkaline lead stains in that the chelating agent, citrate, is in sufficient excess to sequester all lead present, and is less likely to contaminate sections.
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Staining of Tissue Sections for Electron Microscopy with Heavy Metals
TL;DR: Certain hitherto unobserved details are revealed and some sort of specificity exists, although the factors involved are not yet understood.
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Cytochemistry and electron microscopy. The preservation of cellular ultrastructure and enzymatic activity by aldehyde fixation.
TL;DR: A postfixation in osmium tetroxide, even after long periods of storage, developed an image that—notable in the case of glutaraldehyde—was largely indistinguishable from that of tissues fixed under optimal conditions with osmia tetroxides alone.
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A method for staining epoxy sections for light microscopy.
TL;DR: A technique for staining sections of osmium-fixed, epoxy-embedded tissues for light microscopy using aqueous toluidine blue at pH 11.1 and does not require prior removal of embedding medium, which permits better utilization of the full resolving power of the light microscope.
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The initiation of cell division in a contact-inhibited mammalian cell line.
TL;DR: The sequence of event suggests that regulation of RNA synthesis is the means by which contact inhibition controls cell division, and therefore DNA synthesis and cell division are controlled.
Related Papers (5)
Inhibition of Capillary Endothelial Cell Growth by Pericytes and Smooth Muscle Cells
A. Orlidge,Patricia A. D'Amore +1 more