Journal ArticleDOI
Role of the pericyte in wound healing: An ultrastructural study☆
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It is proposed that the pericyte-endothelial “contacts” act as a regulatory mechanism for capillary proliferation.About:
This article is published in Experimental and Molecular Pathology.The article was published on 1970-08-01. It has received 213 citations till now. The article focuses on the topics: Pericyte & Wound healing.read more
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Mathematical Modeling of Capillary Formation and Development in Tumor Angiogenesis: Penetration into the Stroma
TL;DR: A mathematical model for the tumor vascularization theory of tumor growth proposed by Judah Folkman and subsequently established experimentally by him and his coworkers is presented and very good computational agreement with the time of vascularization and the rate of capillary tip growth observed in rabbit cornea experiments is obtained.
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Tumor vessel development and maturation impose limits on the effectiveness of anti-vascular therapy
Michael S. Gee,William N. Procopio,Sosina Makonnen,Michael Feldman,Newman M. Yeilding,Newman M. Yeilding,William M. F. Lee,William M. F. Lee +7 more
TL;DR: The data indicate that the therapeutic susceptibility of tumor vasculature to recombinant murine IL-12 and, potentially, other anti-vascular agents is limited by its level of maturation, and that tumor susceptibility is similarly limited, making pericyte coverage of tumor Vasculature a potential indicator of tumor responsiveness.
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Retinal and choroidal angiogenesis: pathophysiology and strategies for inhibition.
Arup Das,Paul G. McGuire +1 more
TL;DR: Several anti-angiogenic approaches are being developed in animal models to prevent ocular angiogenesis by blocking the key steps of the angiogenic cascade.
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Angiogenesis in brain tumors: pathobiological and clinical aspects
TL;DR: The angiogenic process in glioblastoma multiforma is summarized and other types of tumors for which the efficacy of anti-angiogenic therapy may be studied are suggested.
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Migration and division of progenitor cell populations in periodontal ligament after wounding
TL;DR: Connective tissue cells responding to wounding of the periodontal ligament of the lower first molar in mice were studied using the techniques of radioautography and grain counting to determine if mistakes in identification between fibroblasts and marophages could significantly affect the results.
References
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THE USE OF LEAD CITRATE AT HIGH pH AS AN ELECTRON-OPAQUE STAIN IN ELECTRON MICROSCOPY
TL;DR: The stain reported here differs from previous alkaline lead stains in that the chelating agent, citrate, is in sufficient excess to sequester all lead present, and is less likely to contaminate sections.
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Staining of Tissue Sections for Electron Microscopy with Heavy Metals
TL;DR: Certain hitherto unobserved details are revealed and some sort of specificity exists, although the factors involved are not yet understood.
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Cytochemistry and electron microscopy. The preservation of cellular ultrastructure and enzymatic activity by aldehyde fixation.
TL;DR: A postfixation in osmium tetroxide, even after long periods of storage, developed an image that—notable in the case of glutaraldehyde—was largely indistinguishable from that of tissues fixed under optimal conditions with osmia tetroxides alone.
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A method for staining epoxy sections for light microscopy.
TL;DR: A technique for staining sections of osmium-fixed, epoxy-embedded tissues for light microscopy using aqueous toluidine blue at pH 11.1 and does not require prior removal of embedding medium, which permits better utilization of the full resolving power of the light microscope.
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The initiation of cell division in a contact-inhibited mammalian cell line.
TL;DR: The sequence of event suggests that regulation of RNA synthesis is the means by which contact inhibition controls cell division, and therefore DNA synthesis and cell division are controlled.
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