Journal ArticleDOI
Role of the posterior parietal cortex in updating reaching movements to a visual target.
Michel Desmurget,Michel Desmurget,Charles M. Epstein,Robert Turner,Claude Prablanc,G. E. Alexander,Scott T. Grafton +6 more
Reads0
Chats0
TLDR
Transcranial magnetic stimulation was applied over the left PPC during target presentation and disrupted path corrections that normally occur in response to target jumps, but had no effect on those directed at stationary targets.Abstract:
The exact role of posterior parietal cortex (PPC) in visually directed reaching is unknown. We propose that, by building an internal representation of instantaneous hand location, PPC computes a dynamic motor error used by motor centers to correct the ongoing trajectory. With unseen right hands, five subjects pointed to visual targets that either remained stationary or moved during saccadic eye movements. Transcranial magnetic stimulation (TMS) was applied over the left PPC during target presentation. Stimulation disrupted path corrections that normally occur in response to target jumps, but had no effect on those directed at stationary targets. Furthermore, left-hand movement corrections were not blocked, ruling out visual or oculomotor effects of stimulation.read more
Citations
More filters
Journal ArticleDOI
Chondroitinase ABC promotes functional recovery after spinal cord injury
Elizabeth J. Bradbury,Lawrence D. F. Moon,Lawrence D. F. Moon,Reena J Popat,V.R. King,GS Bennett,Preena N. Patel,James W. Fawcett,Stephen B. McMahon +8 more
TL;DR: It is demonstrated that CSPGs are important inhibitory molecules in vivo and suggested that their manipulation will be useful for treatment of human spinal injuries.
Journal ArticleDOI
Coding and use of tactile signals from the fingertips in object manipulation tasks
TL;DR: Analysis of signals in tactile afferent neurons and central processes in humans reveals how contact events are encoded and used to monitor and update task performance.
Journal ArticleDOI
Forward modeling allows feedback control for fast reaching movements
TL;DR: The ability of the motor system to estimate the future state of the limb might be an evolutionary substrate for mental operations that require an estimate of sequelae in the immediate future.
Journal ArticleDOI
Two visual systems re-viewed.
A. D. Milner,Melvyn A. Goodale +1 more
TL;DR: In the present article some essential concepts inherent in the model are summarized, and certain clarifications and refinements are offered.
Journal ArticleDOI
A computational neuroanatomy for motor control
Reza Shadmehr,John W. Krakauer +1 more
TL;DR: It is argued that the lesion approach and theoretical motor control can mutually inform each other and one may identify distinct motor control processes from computational models and map them onto specific deficits in patients.
References
More filters
Journal ArticleDOI
An Internal Model for Sensorimotor Integration
TL;DR: A sensorimotor integration task was investigated in which participants estimated the location of one of their hands at the end of movements made in the dark and under externally imposed forces, providing direct support for the existence of an internal model.
Journal ArticleDOI
A Closed-Loop Theory of Motor Learning
TL;DR: A closed-loop theory for learning simple movements is presented and empirical generalizations from the literature are stated, and the theory is used to explain them.
Journal ArticleDOI
Multimodal representation of space in the posterior parietal cortex and its use in planning movements
TL;DR: A review of recent studies showing that the encoding of intentions to make movements is also among the cognitive functions of the posterior parietal cortex is reviewed.
Book
The neural and behavioural organization of goal-directed movements
TL;DR: The author's account is based upon experimental data from human and animal work with particular emphasis on illustrative clinical cases, and concepts derived from cognitive psychology in the study of motor control have opened new fields of investigation concerning the mental representation of goal-directed movements.