Safety and Tolerability of an Eye Drop Based on 0.6% Povidone-Iodine Nanoemulsion in Dry Eye Patients.
Giovanni William Oliverio,Rosaria Spinella,Elisa Imelde Postorino,Leandro Inferrera,Emanuela Aragona,Pasquale Aragona +5 more
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In this paper, the authors evaluated safety and tolerability on the ocular surface of an anti-septic formulation containing 0.6% povidone-iodine (0.6%) for a 4-week period.Abstract:
Purpose: To evaluate safety and tolerability on the ocular surface of an anti-septic formulation containing 0.6% povidone–iodine (0.6% PVI) for a 4 week period. Methods: An observational, prospecti...read more
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Lipid-Based Nanocarriers as Topical Drug Delivery Systems for Intraocular Diseases.
Jose Navarro-Partida,Carlos Rodrigo Castro-Castaneda,Francisco J Santa Cruz-Pavlovich,Luis Abraham Aceves-Franco,Tomer Ori Guy,Arturo Santos +5 more
TL;DR: In this article, a review of lipid-based nanocarriers used in topical ophthalmic formulations for intraocular drug delivery is presented, including proteins, peptides and genetic material.
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Short-Term Effects of a Novel Eye Mask Producing Heat and Vibration for the Treatment of Meibomian Gland Dysfunction: A Pilot Study
TL;DR: In this paper, the authors investigated the short-term effects on tear film parameters and ocular symptoms of a novel eye mask producing heat and vibration developed for the treatment of dry eye disease owing to meibomian gland dysfunction (MGD).
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Low-Concentration (0.66%) Povidone Iodine Treatment of a Corneal Ulcer in a Rheumatoid Arthritis Patient.
TL;DR: In this paper, the resolution of a peripheral ulcerative keratitis case by means of treatment with 0.66% povidone iodine (3 times/day) given alone for 5 weeks and then associated with serum eyedrops was shown.
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Combined intense pulsed light and low-level light therapy for the treatment of refractory Meibomian gland dysfunction
TL;DR: This study confirmed the efficacy and safety of combined IPL and LLLT demonstrating its superiority compared to topical treatment.
Journal ArticleDOI
Neurotrophic Keratopathy in Systemic Diseases: A Case Series on Patients Treated With rh-NGF
Alessandro Meduri,G. Oliverio,Antonio Valastro,Claudia Azzaro,Umberto Camellin,F. Franchina,Leandro Inferrera,Anna M. Roszkowska,Pasquale Aragona +8 more
TL;DR: The post-neuroma surgery was the most common cause of NK and severe grade was clinically more represented and the rh-NGF proved effective to promote corneal recovery with all defects healed after the treatment.
References
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Role of the Microbiota in Immunity and Inflammation
Yasmine Belkaid,Timothy W. Hand +1 more
TL;DR: In high-income countries, overuse of antibiotics, changes in diet, and elimination of constitutive partners, such as nematodes, may have selected for a microbiota that lack the resilience and diversity required to establish balanced immune responses.
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Reliability and validity of the Ocular Surface Disease Index.
TL;DR: The OSDI is a valid and reliable instrument for measuring the severity of dry eye disease, and it possesses the necessary psychometric properties to be used as an end point in clinical trials.
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TFOS DEWS II Definition and Classification Report
Jennifer P. Craig,Kelly K. Nichols,Esen K. Akpek,Barbara Caffery,Harminder S Dua,Choun Ki Joo,Zuguo Liu,J. Daniel Nelson,J. Daniel Nelson,Jason J. Nichols,Kazuo Tsubota,Fiona Stapleton +11 more
TL;DR: The new definition recognizes the multifactorial nature of dry eye as a disease where loss of homeostasis of the tear film is the central pathophysiological concept and central to the scheme is a positive diagnosis of DED with signs and symptoms, and this is directed towards management to restore homeostosis.
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