Journal ArticleDOI
Scrophularia lucida L. as a valuable source of bioactive compounds for pharmaceutical applications: In vitro antioxidant, anti-inflammatory, enzyme inhibitory properties, in silico studies, and HPLC profiles.
Gokhan Zengin,Azzurra Stefanucci,Maria João Rodrigues,Adriano Mollica,Luísa Custódio,Muhammad Zakariyyah Aumeeruddy,Mohamad Fawzi Mahomoodally +6 more
TLDR
Investigation into the biological properties of various solvent extracts of the roots and aerial parts of Scrophularia lucida based on its antioxidant, anti‐inflammatory, and enzyme inhibitory activities revealed that the solvent extracts differed in their biological effectiveness.About:
This article is published in Journal of Pharmaceutical and Biomedical Analysis.The article was published on 2019-01-05. It has received 55 citations till now. The article focuses on the topics: Ethyl acetate & Rosmarinic acid.read more
Citations
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Advances on the antioxidant peptides from edible plant sources
TL;DR: This review pays particular attention to studies which successfully determined the sequences of antioxidant peptides under investigation, particularly their biological effects, mechanisms, and structure-activity relationship.
Journal ArticleDOI
Phytochemical profiling, in vitro biological properties and in silico studies on Caragana ambigua stocks (Fabaceae): A comprehensive approach
Saima Khan,Mamona Nazir,Naheed Raiz,Muhammad Saleem,Gokhan Zengin,Gazala Fazal,Hammad Saleem,Hammad Saleem,Mahreen Mukhtar,Muhammad Imran Tousif,Rasool Baksh Tareen,Hassan H. Abdallah,Hassan H. Abdallah,Fawzi M. Mahomoodally +13 more
TL;DR: In this article, the chemical and biological effects of different extracts of different Caragana ambigua stocks (Fabaceae) were determined using standard spectrophotometric methods, whereas, the secondary metabolites composition was established by ultra-high performance liquid chromatography-mass spectrometry (UHPLC-MS) analysis.
Journal ArticleDOI
Supercritical carbon dioxide extraction of plant phytochemicals for biological and environmental applications - A review
Thanigaivelan Arumugham,Krishnamoorthy Rambabu,Shadi W. Hasan,Pau Loke Show,Jörg Rinklebe,Jörg Rinklebe,Fawzi Banat +6 more
TL;DR: Recently, supercritical fluid CO2 extraction (SFE) has emerged as a promising and pervasive technology over conventional extraction techniques for various applications, especially for bioactive compounds extraction and environmental pollutants removal.
Journal ArticleDOI
Combination of phenolic profiles, pharmacological properties and in silico studies to provide new insights on Silene salsuginea from Turkey.
Gokhan Zengin,Maria João Rodrigues,Hassan H. Abdallah,Luísa Custódio,Azzurra Stefanucci,Muhammad Zakariyyah Aumeeruddy,Adriano Mollica,Kannan R.R. Rengasamy,Mohamad Fawzi Mahomoodally +8 more
TL;DR: Extracts of S. salsuginea are a potential source of functional food ingredients but need further analytical experiments to explore its complexity of chemical compounds and pharmacological properties as well as using in vivo toxicity models to establish its maximum tolerated dose.
Journal ArticleDOI
Iberian dry-cured ham as a potential source of α-glucosidase-inhibitory peptides
TL;DR: The α-glucosidase inhibitory activity of previously identified bioactive peptides in Spanish dry-cured ham such as AEEEYPDL and LGVGG was established, confirming their multifunctionality.
References
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Journal ArticleDOI
Biologically Active Substances from the Genus Scrophularia
TL;DR: This review summarizes mainly the biological activity associated with this genus, which has been used since ancient times as folk remedies for some medical treatments including scrophula, scabies, tumours and inflammatory affections.
Journal ArticleDOI
Iridoid glycosides isolated from Scrophularia dentata Royle ex Benth. and their anti-inflammatory activity
Liuqiang Zhang,Tiantian Zhu,Fei Qian,Jin-Wen Xu,Gaawe Dorje,Zhili Zhao,Fujiang Guo,Yiming Li +7 more
TL;DR: Bioassay showed that compounds 7 and 11 had significant inhibitory effect against NF-κB activation with IC50 value of 43.7 μM and 1.02 μM respectively.
Journal ArticleDOI
A comparative study on phytochemical screening, quantification of phenolic contents and antioxidant properties of different solvent extracts from various parts of Pistacia lentiscus L
TL;DR: In this paper, the authors focus on screening of phytochemical constituents, the variation in the total phenolic content and the antioxidant capacities from different parts (fruits, twigs and leaves) of Pistacia lentiscus L., from two different regions of Morocco; Moulay Idriss Zerhoun (MIZ) and Melloussa (MLS) was studied.
Journal ArticleDOI
The role of birds and insects in pollination shifts of Scrophularia (Scrophulariaceae).
María Luisa Navarro-Pérez,Josefa López,Mario Fernández-Mazuecos,Tomás Rodríguez-Riaño,Pablo Vargas,Ana Ortega-Olivencia +5 more
TL;DR: It is shown that a role of birds in pollination of Scrophularia may not have been effective in the Miocene-Pliocene, but bird pollination that shows its origin in the Pliocene-Pleistocene is still operating independently in different islands and continents.
Journal ArticleDOI
A Multidirectional Perspective for Novel Functional Products: In vitro Pharmacological Activities and In silico Studies on Ononis natrix subsp. hispanica.
Serife Yerlikaya,Gokhan Zengin,Adriano Mollica,Mehmet Cengiz Baloglu,Yasemin Celik Altunoglu,Abdurrahman Aktumsek +5 more
TL;DR: The results clearly indicate that O. natrix subsp.