Journal ArticleDOI
Semen cryobanking for men with cancer — Criteria change
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TLDR
Existing criteria for pretherapy semen cryobanking should be revised in view of successful pregnancies even with the use of semen with low spermatozoal densities and motilities, as well as other realized clinical efficacies of ART.About:
This article is published in Fertility and Sterility.The article was published on 1992-11-01. It has received 173 citations till now. The article focuses on the topics: Assisted reproductive technology & Semen.read more
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Journal ArticleDOI
American Society of Clinical Oncology Recommendations on Fertility Preservation in Cancer Patients
Stephanie J. Lee,Leslie R. Schover,Ann H. Partridge,Pasquale Patrizio,W. Hamish B. Wallace,Karen L. Hagerty,Lindsay Nohr Beck,Lawrence V. Brennan,Kutluk Oktay +8 more
TL;DR: Fertility preservation is often possible in people undergoing treatment for cancer and should be considered as early as possible during treatment planning, to preserve the full range of options.
Journal ArticleDOI
Role of sperm chromatin abnormalities and DNA damage in male infertility
Ashok Agarwal,Tamer M. Said +1 more
TL;DR: Screening for sperm DNA damage may provide useful information in cases of male idiopathic infertility and in those men pursuing assisted reproduction, and treatment should include methods for prevention of spermDNA damage.
Journal ArticleDOI
Fertility Preservation in Adolescents and Young Adults With Cancer
TL;DR: Given the competing demands of providing complicated and detailed information about cancer treatment, the evolving information related to fertility preservation, and the ethical issues involved, it may be preferable, where possible, to have a specialized team, rather than the primary oncologist, address these issues with AYA patients.
Journal ArticleDOI
Assessment of DNA integrity and morphology of ejaculated spermatozoa from fertile and infertile men before and after cryopreservation
TL;DR: Investigation of the effects of cryopreservation on both DNA integrity and morphology of spermatozoa from fertile and infertile men found it had a detrimental effect on morphology of semen and prepared samples from fertile, and sperm morphology was significantly damaged by freeze-thawing.
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Human Sperm Cryopreservation: Update on Techniques, Effect on DNA Integrity, and Implications for ART
TL;DR: Sperm cryopreservation is an important component of fertility management and much of its successful application seems to affect the reproductive outcome of assisted reproduction technologies (ART): appropriate use of cryoprotectants before and sperm selection technologies after cryop Reservation seem to have the greatest impact on preventing DNA fragmentation, thus improving sperm cryosurvival rates.
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Journal ArticleDOI
Gonadal function in men with testis cancer.
TL;DR: A group of 218 patients with unilateral germinal testicular cancer was investigated with biopsy from the contralateral testis and/or semen and hormone analyses after orchidectomy but before irradiation and chemotherapy as mentioned in this paper.
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In vitro fertilization: a treatment for male infertility
Jacques Cohen,Robert G Edwards,Carole B. Fehilly,Simon Fishel,Jonathan Hewitt,J. M. Purdy,George F. Rowland,P. C. Steptoe,John Webster +8 more
TL;DR: The collection of split ejaculates and the careful preparation of spermatozoa, by sedimentation and layering methods, proved to be beneficial, improving sperm motility and raising the chance of fertilization.
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Male gonadal dysfunction in Hodgkin's disease. A prospective study.
TL;DR: Data indicate that a proportion of men have gonadal dysfunction prior to treatment for Hodgkin's disease and subsequent chemotherapy, and it is clear that cytotoxic therapy induces infertility.
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Semen Analysis in Testicular Cancer and Hodgkin's Disease: Pre‐ and Post‐Treatment Findings and Implications for Cryopreservation
TL;DR: Surprisingly, 24% of men receiving chemotherapy recovered sperm counts greater than 10 million per ml up to 3 years after therapy, and recovery was seen in 35% of 23 men with initially poor sperm counts, but in only 26% of 19 with good initial counts.
Journal Article
Bone-marrow transplantation in acute leukaemia.
RobertPeter Gale,Stephen A. Feig,Winston G. Ho,Peter M. Falk,Drew J. Winston,Lowell S. Young,Gerhard Opelz,Tesler A,R. S. Sparkes,Graze Pr,Sarna G,D W Golde,Mary C. Territo,Yvonne J. Bryson,Gossett T,Naiem F,Fawzy F,Haskell C,John L. Fahey,Cline Mj +19 more
TL;DR: Bone-marrow transplantation appears to offer a small but distinct possibility of long-term survival in patients with acute leukaemia resistant to conventional therapy as mentioned in this paper, however, the transplant group were rendered free of detectable leukemia for periods of from 36 days to more than 2 1/2 years, while only 6 patients in the chemotherapy group achieved a haematological remission.