Serum anti‐Müllerian hormone is more strongly related to ovarian follicular status than serum inhibin B, estradiol, FSH and LH on day 3
TLDR
Serum AMH levels were more robustly correlated with the number of early antral follicles than inhibin B, E(2), FSH and LH on cycle day 3, suggesting that AMH may reflect ovarian follicular status better than the usual hormone markers.Citations
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Journal ArticleDOI
Ovarian Aging: Mechanisms and Clinical Consequences
TL;DR: Improved knowledge of the ovarian ageing mechanisms may ultimately provide tools for prediction of menopause and manipulation of the early steps of folliculogenesis for the purpose of contraception and fertility lifespan extension.
Journal ArticleDOI
Anti-Müllerian hormone (AMH) as a predictive marker in assisted reproductive technology (ART)
A. La Marca,Giovanna Sighinolfi,D Radi,Cindy Argento,Enrica Baraldi,A. Carducci Artenisio,Gaspare Stabile,Annibale Volpe +7 more
TL;DR: AMH seems to be a better marker in predicting ovarian response to controlled ovarian stimulation than age of the patient, FSH, estradiol and inhibin B, and a similar performance for AMH and antral follicular count has been reported.
Journal ArticleDOI
Pregnancy after transplantation of cryopreserved ovarian tissue in a patient with ovarian failure after chemotherapy
Dror Meirow,Jacob Levron,Talia Eldar-Geva,Izhar Hardan,Eduard Fridman,Yaron Zalel,Eyal Schiff,Jehoshua Dor +7 more
TL;DR: Premenopausal women who undergo high-dose chemotherapy have a very high risk of ovarian failure and cryopreservation of ovarian tissue with subsequent autotransplantation has effectively preserved fertility in an animal model but its efficacy in humans has been uncertain.
Journal ArticleDOI
The physiology and clinical utility of anti-Müllerian hormone in women
Didier Dewailly,Claus Yding Andersen,Adam H. Balen,Frank J. M. Broekmans,Nafi Dilaver,Renato Fanchin,Georg Griesinger,Tom Kelsey,Antonio La Marca,C.B. Lambalk,Helen D. Mason,Scott M. Nelson,Jenny A. Visser,W. Hamish B. Wallace,Richard A. Anderson +14 more
TL;DR: There is a linear relationship between AMH and oocyte yield after ovarian stimulation, which is of value in predicting ovarian hyperstimulation, and the submerged part of the iceberg of follicle growth, i.e. the intrinsic, so-called 'acyclic' ovarian activity is measured.
Journal ArticleDOI
Anti-Müllerian hormone: a new marker for ovarian function
TL;DR: This review summarizes recent findings concerning AMH and its role as a marker for the quantitative aspect of ovarian reserve as well as ovarian dysfunction.
References
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Journal ArticleDOI
Measurement of dimeric inhibin B throughout the human menstrual cycle.
TL;DR: Using this immunoassay, it was found that the plasma concentration of inhibin B rose rapidly in the early follicular phase to a peak of 85.2 +/- 9.6 pg/mL on the day after the intercycle FSH rise, then fell progressively during the remainder of the follicular phases, which suggests that these forms may have different physiological roles.
Journal ArticleDOI
Antimüllerian hormone serum levels: a putative marker for ovarian aging.
TL;DR: Serum concentrations of antimüllerian hormone decreased over time in young normo-ovulatory women, whereas other markers associated with ovarian aging did not change, and concentration correlate with the number of antral follicles and age and less strongly with FSH level.
Journal ArticleDOI
Anti-Müllerian Hormone Inhibits Initiation of Primordial Follicle Growth in the Mouse Ovary
Alexandra L. L. Durlinger,Maria J. G. Gruijters,Piet Kramer,Bas Karels,Holly A. Ingraham,Mark W. Nachtigal,Jan Th. J. Uilenbroek,J. Anton Grootegoed,Axel P. N. Themmen +8 more
TL;DR: It is suggested that AMH inhibits initia- tion of primordial follicle growth and therefore functions as an inhibitory growth factor in the ovary during these early stages of folliculogenesis.
Journal ArticleDOI
Anti-Müllerian Hormone Attenuates the Effects of FSH on Follicle Development in the Mouse Ovary
Alexandra L. L. Durlinger,Maria J. G. Gruijters,Piet Kramer,Bas Karels,T. Rajendra Kumar,Martin M. Matzuk,Ursula M. Rose,Frank H. de Jong,Jan Th. J. Uilenbroek,J. Anton Grootegoed,Axel P. N. Themmen +10 more
TL;DR: It was shown that FSH-stimulated preantral follicle growth is attenuated in the presence of AMH, and in immature AMH-deficient females, more follicles start to grow under the influence of exogenous FSH than in their wild-type littermates.
Journal ArticleDOI
Early follicular serum müllerian-inhibiting substance levels are associated with ovarian response during assisted reproductive technology cycles.
TL;DR: Data demonstrate an association between early follicular phase serum MIS and the number of retrieved oocytes in women undergoing ovulation induction in preparation for assisted reproductive technology (ART).